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CATH Superfamily 1.10.340.30

Hypothetical protein; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Hypothetical protein; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2082: Ada regulatory protein alkA

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA-3-methyladenine glycosylase II. [EC: 3.2.2.21]
Hydrolysis of alkylated DNA, releasing 3-methyladenine, 3-methylguanine, 7-methylguanine and 7-methyladenine.
    		 18 A0A045JVF3 A0A0E8B7H2 A0A0H3LEZ4 A0A0H3MCK3 A0A0H3P332 A0A0K2HUV7 A0A0T7PGX2 A0A0T9DIW2 A0A120IWE4 A0A120J0N2
    (8 more...)
    Methylated-DNA--[protein]-cysteine S-methyltransferase. [EC: 2.1.1.63]
    DNA (containing 6-O-methylguanine) + protein L-cysteine = DNA (without 6-O-methylguanine) + protein S-methyl-L-cysteine.
    • This protein is involved in the repair of alkylated DNA.
    • It acts only on the alkylated DNA (cf. EC 3.2.2.20 and EC 3.2.2.21).
    • This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
    		 17 A0A045JVF3 A0A0E8B7H2 A0A0H3LEZ4 A0A0H3MCK3 A0A0H3P332 A0A0K2HUV7 A0A0T9DIW2 A0A120IWE4 A0A120J0N2 A0A197ITR2
    (7 more...)
    Methylphosphotriester-DNA--[protein]-cysteine S-methyltransferase. [EC: 2.1.1.n11]
    DNA (containing Sp-methylphosphotriester) + protein L-cysteine = DNA (without Sp-methylphosphotriester) + protein S-methyl-L-cysteine.
    • This protein is involved in the repair of Sp diastereomers of DNA methylphosphotriester lesions.
    • This enzyme catalyzes only one turnover and therefore is not strictly catalytic.
    • The enzyme from the bacterium Escherichia coli also has the activity of EC 2.1.1.63 while the enzyme from Bacillus subtilis does not.
    		 6 A0A0E8B7H2 A0A0H3LEZ4 A5U216 I6XXP6 P9WJW2 P9WJW3
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