The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Hypothetical protein af1432
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17506: Deoxynucleoside triphosphate triphosphohydrolase S...

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 20 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
DGTPase activity GO:0008832
Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
DGTP binding GO:0032567
Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Ribonuclease activity GO:0004540
Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
2 Q0VCA5 (/ISS) Q60710 (/ISS)
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
1 Q9Y3Z3 (/IDA)
Nucleic acid binding GO:0003676
Interacting selectively and non-covalently with any nucleic acid.
1 Q60710 (/ISO)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q9Y3Z3 (/IDA)
RNA binding GO:0003723
Interacting selectively and non-covalently with an RNA molecule or a portion thereof.
1 Q60710 (/ISO)
Ribonuclease activity GO:0004540
Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
1 Q9Y3Z3 (/IDA)
Ribonuclease activity GO:0004540
Catalysis of the hydrolysis of phosphodiester bonds in chains of RNA.
1 Q60710 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q9Y3Z3 (/IPI)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q9Y3Z3 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
1 Q60710 (/ISO)
DGTPase activity GO:0008832
Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.
1 Q9Y3Z3 (/IDA)
DGTPase activity GO:0008832
Catalysis of the reaction: dGTP + H(2)O = 2'-deoxyguanosine + 2 H(+) + triphosphate.
1 Q60710 (/ISO)
Triphosphoric monoester hydrolase activity GO:0016793
Catalysis of the hydrolysis of a triphosphoester to give a triphosphate group and a free hydroxyl group.
1 Q9Y3Z3 (/EXP)
DGTP binding GO:0032567
Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate.
1 Q9Y3Z3 (/IDA)
DGTP binding GO:0032567
Interacting selectively and non-covalently with dGTP, deoxyguanosine triphosphate.
1 Q60710 (/ISO)

There are 21 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
DGTP catabolic process GO:0006203
The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
DATP catabolic process GO:0046061
The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
6 A0A023VTS2 (/ISS) Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
2 Q502K2 (/IMP) Q9Y3Z3 (/IMP)
DGTP catabolic process GO:0006203
The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
1 Q9Y3Z3 (/IDA)
DGTP catabolic process GO:0006203
The chemical reactions and pathways resulting in the breakdown of dGTP, guanosine triphosphate.
1 Q60710 (/ISO)
Immune response GO:0006955
Any immune system process that functions in the calibrated response of an organism to a potential internal or invasive threat.
1 Q9Y3Z3 (/NAS)
Deoxyribonucleotide catabolic process GO:0009264
The chemical reactions and pathways resulting in the breakdown of a deoxyribonucleotide, a compound consisting of deoxyribonucleoside (a base linked to a deoxyribose sugar) esterified with a phosphate group at either the 3' or 5'-hydroxyl group of the sugar.
1 Q9Y3Z3 (/TAS)
Modulation by host of viral RNA genome replication GO:0044830
A process in which a host organism modulates the frequency, rate or extent of viral RNA genome replication.
1 A0A023VTS2 (/IMP)
Regulation of innate immune response GO:0045088
Any process that modulates the frequency, rate or extent of the innate immune response, the organism's first line of defense against infection.
1 Q60710 (/ISO)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 A0A023VTS2 (/IMP)
DATP catabolic process GO:0046061
The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
1 Q9Y3Z3 (/IDA)
DATP catabolic process GO:0046061
The chemical reactions and pathways resulting in the breakdown of dATP, deoxyadenosine triphosphate (2'-deoxyadenosine 5'-triphosphate).
1 Q60710 (/ISO)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 Q9Y3Z3 (/IDA)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 Q60710 (/ISO)
Protein homotetramerization GO:0051289
The formation of a protein homotetramer, a macromolecular structure consisting of four noncovalently associated identical subunits.
1 A0A023VTS2 (/ISS)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
1 Q9Y3Z3 (/IMP)
Defense response to virus GO:0051607
Reactions triggered in response to the presence of a virus that act to protect the cell or organism.
1 Q60710 (/ISO)
Type I interferon signaling pathway GO:0060337
A series of molecular signals initiated by the binding of a type I interferon to a receptor on the surface of a cell, and ending with regulation of a downstream cellular process, e.g. transcription. Type I interferons include the interferon-alpha, beta, delta, episilon, zeta, kappa, tau, and omega gene families.
1 Q9Y3Z3 (/TAS)
Negative regulation of viral life cycle GO:1903901
Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.
1 A0A023VTS2 (/IMP)

There are 12 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q0VCA5 (/ISS) Q502K2 (/ISS) Q5ZJL9 (/ISS) Q60710 (/ISS) Q6INN8 (/ISS)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q9Y3Z3 (/NAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9Y3Z3 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 A0A023VTS2 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q60710 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9Y3Z3 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q60710 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 A0A023VTS2 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q9Y3Z3 (/TAS)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q9Y3Z3 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q60710 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 A0A023VTS2 (/ISS)