The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 665: Kv channel-interacting protein 4
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 7 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | Q6PHZ8 (/IDA) Q6PIL6 (/IDA) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
2 | Q8HYN7 (/ISS) Q99MG9 (/ISS) |
|
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
|
1 | Q6PHZ8 (/ISO) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q99MG9 (/IPI) |
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
1 | Q99MG9 (/IDA) |
|
Potassium channel regulator activity GO:0015459
Modulates potassium channel activity via direct interaction interaction with a potassium channel (binding or modification).
|
1 | Q6PHZ8 (/IMP) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Regulation of potassium ion transmembrane transport GO:1901379
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Cardiac conduction GO:0061337
Transfer of an organized electrical impulse across the heart to coordinate the contraction of cardiac muscles. The process begins with generation of an action potential (in the sinoatrial node (SA) in humans) and ends with a change in the rate, frequency, or extent of the contraction of the heart muscles.
|
1 | Q6PIL6 (/TAS) |
|
Protein localization to plasma membrane GO:0072659
A process in which a protein is transported to, or maintained in, a specific location in the plasma membrane.
|
1 | Q99MG9 (/IDA) |
|
Regulation of potassium ion transmembrane transport GO:1901379
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | Q99MG9 (/IDA) |
|
Regulation of potassium ion transmembrane transport GO:1901379
Any process that modulates the frequency, rate or extent of potassium ion transmembrane transport.
|
1 | Q6PHZ8 (/IMP) |
There are 13 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
3 | Q6PHZ8 (/ISS) Q6PIL6 (/ISS) Q8HYN7 (/ISS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
2 | Q6PIL6 (/IDA) Q99MG9 (/IDA) |
|
Voltage-gated potassium channel complex GO:0008076
A protein complex that forms a transmembrane channel through which potassium ions may cross a cell membrane in response to changes in membrane potential.
|
2 | Q6PHZ8 (/IDA) Q99MG9 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q6PIL6 (/IDA) |
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
1 | Q6PHZ8 (/ISO) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q99MG9 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q6PHZ8 (/ISO) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q6PIL6 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q99MG9 (/IDA) |
|
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
|
1 | Q99MG9 (/IDA) |
|
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
|
1 | Q99MG9 (/IDA) |