The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 32677: Neuronal calcium sensor 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 36 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
26 P21457 (/IPI) P37235 (/IPI) P37235 (/IPI) P42324 (/IPI) P42324 (/IPI) P46065 (/IPI) P46065 (/IPI) P61601 (/IPI) P61601 (/IPI) P61602 (/IPI)
(16 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
15 A0A0R4IPJ4 (/IDA) A0A0R4IPX8 (/IDA) P37236 (/IDA) P42325 (/IDA) P42325 (/IDA) P46065 (/IDA) P46065 (/IDA) P62168 (/IDA) Q09711 (/IDA) Q1LWS5 (/IDA)
(5 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
15 A0A0R4IPJ4 (/ISS) A0A0R4IPX8 (/ISS) P43080 (/ISS) P43080 (/ISS) P43081 (/ISS) P43081 (/ISS) P79880 (/ISS) P79880 (/ISS) Q06389 (/ISS) Q06389 (/ISS)
(5 more)
Calcium sensitive guanylate cyclase activator activity GO:0008048
Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.
15 A0A0R4IPJ4 (/IDA) A0A0R4IPX8 (/IDA) D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA) P37236 (/IDA) P43081 (/IDA) P43081 (/IDA) P46065 (/IDA) P46065 (/IDA)
(5 more)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
10 P37235 (/TAS) P37235 (/TAS) P62166 (/TAS) P62167 (/TAS) P62168 (/TAS) P62762 (/TAS) P84076 (/TAS) P84076 (/TAS) Q8BNY6 (/TAS) Q9UM19 (/TAS)
Calcium sensitive guanylate cyclase activator activity GO:0008048
Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.
7 P37236 (/ISS) P43080 (/ISS) P43080 (/ISS) P46065 (/ISS) P46065 (/ISS) P79880 (/ISS) P79880 (/ISS)
Guanylate cyclase activator activity GO:0030250
Binds to and increases the activity of guanylate cyclase.
7 A0A0R4IPJ4 (/ISS) A0A0R4IPX8 (/ISS) Q1LWS5 (/ISS) Q1LWS5 (/ISS) Q5MAC8 (/ISS) Q90WX4 (/ISS) Q90WX4 (/ISS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
6 P61601 (/IDA) P61601 (/IDA) P84074 (/IDA) P84074 (/IDA) Q5PQN0 (/IDA) Q5PQN0 (/IDA)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
6 P61602 (/ISS) P61602 (/ISS) P84075 (/ISS) P84075 (/ISS) P84076 (/ISS) P84076 (/ISS)
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
6 P62166 (/ISS) P62167 (/ISS) Q2V8Y7 (/ISS) Q5RC90 (/ISS) Q8BNY6 (/ISS) Q91614 (/ISS)
Guanylate cyclase regulator activity GO:0030249
Modulates the activity of guanylate cyclase.
6 P43080 (/ISS) P43080 (/ISS) P46065 (/ISS) P46065 (/ISS) P79880 (/ISS) P79880 (/ISS)
Actin binding GO:0003779
Interacting selectively and non-covalently with monomeric or multimeric forms of actin, including actin filaments.
4 P84075 (/ISO) P84075 (/ISO) Q91X97 (/ISO) Q91X97 (/ISO)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
4 P61602 (/NAS) P61602 (/NAS) P84074 (/NAS) P84074 (/NAS)
Enzyme activator activity GO:0008047
Binds to and increases the activity of an enzyme.
2 Q06389 (/IDA) Q06389 (/IDA)
Calcium sensitive guanylate cyclase activator activity GO:0008048
Binds to and increases the activity of guanylate cyclase in response to a change in calcium ion concentration.
2 P43080 (/TAS) P43080 (/TAS)
Ligand-gated ion channel activity GO:0015276
Enables the transmembrane transfer of an ion by a channel that opens when a specific ligand has been bound by the channel complex or one of its constituent parts.
2 P61601 (/TAS) P61601 (/TAS)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
2 P61601 (/IDA) P61601 (/IDA)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
2 Q91X97 (/ISO) Q91X97 (/ISO)
Tubulin binding GO:0015631
Interacting selectively and non-covalently with monomeric or multimeric forms of tubulin, including microtubules.
2 P61602 (/ISS) P61602 (/ISS)
Kinase binding GO:0019900
Interacting selectively and non-covalently with a kinase, any enzyme that catalyzes the transfer of a phosphate group.
2 P84076 (/IPI) P84076 (/IPI)
Guanylate cyclase regulator activity GO:0030249
Modulates the activity of guanylate cyclase.
2 P46065 (/IDA) P46065 (/IDA)
Guanylate cyclase regulator activity GO:0030249
Modulates the activity of guanylate cyclase.
2 P43081 (/IGI) P43081 (/IGI)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
2 P61601 (/IDA) P61601 (/IDA)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
2 Q91X97 (/ISO) Q91X97 (/ISO)
Clathrin binding GO:0030276
Interacting selectively and non-covalently with a clathrin heavy or light chain, the main components of the coat of coated vesicles and coated pits, and which also occurs in synaptic vesicles.
2 P61602 (/ISS) P61602 (/ISS)
Alpha-tubulin binding GO:0043014
Interacting selectively and non-covalently with the microtubule constituent protein alpha-tubulin.
2 Q5PQN0 (/IDA) Q5PQN0 (/IDA)
Magnesium ion binding GO:0000287
Interacting selectively and non-covalently with magnesium (Mg) ions.
1 P62168 (/IDA)
Voltage-gated calcium channel activity GO:0005245
Enables the transmembrane transfer of a calcium ion by a voltage-gated channel. A voltage-gated channel is a channel whose open state is dependent on the voltage across the membrane in which it is embedded.
1 P62168 (/IMP)
Calcium channel regulator activity GO:0005246
Modulates the activity of a calcium channel.
1 P35332 (/IDA)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q09711 (/EXP)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 G3V6G4 (/IMP)
Protein C-terminus binding GO:0008022
Interacting selectively and non-covalently with a protein C-terminus, the end of any peptide chain at which the 1-carboxy function of a constituent amino acid is not attached in peptide linkage to another amino-acid residue.
1 P35332 (/IPI)
Calcium-dependent protein kinase inhibitor activity GO:0008427
Stops, prevents or reduces the activity of a calcium-dependent protein kinase.
1 P62168 (/TAS)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P62168 (/IPI)
Protein domain specific binding GO:0019904
Interacting selectively and non-covalently with a specific domain of a protein.
1 P35332 (/IPI)
1-phosphatidylinositol 4-kinase activator activity GO:0098744
Binds to and increases the activity of 1-phosphatidylinositol 4-kinase.
1 Q09711 (/IDA)

There are 63 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of neuron projection development GO:0010975
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
6 P62166 (/ISS) P62167 (/ISS) Q2V8Y7 (/ISS) Q5RC90 (/ISS) Q8BNY6 (/ISS) Q91614 (/ISS)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
6 P43080 (/ISS) P43080 (/ISS) P43081 (/ISS) P43081 (/ISS) P79880 (/ISS) P79880 (/ISS)
Positive regulation of guanylate cyclase activity GO:0031284
Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.
5 D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA) P46065 (/IDA) P46065 (/IDA)
Positive regulation of guanylate cyclase activity GO:0031284
Any process that activates or increases the frequency, rate or extent of guanylate cyclase activity.
4 P43080 (/ISS) P43080 (/ISS) P79880 (/ISS) P79880 (/ISS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
3 G3V6G4 (/IMP) P43081 (/IMP) P43081 (/IMP)
Vesicle-mediated transport GO:0016192
A cellular transport process in which transported substances are moved in membrane-bounded vesicles; transported substances are enclosed in the vesicle lumen or located in the vesicle membrane. The process begins with a step that directs a substance to the forming vesicle, and includes vesicle budding and coating. Vesicles are then targeted to, and fuse with, an acceptor membrane.
3 P61601 (/NAS) P61601 (/NAS) Q9VWX8 (/NAS)
Regulation of rhodopsin mediated signaling pathway GO:0022400
Any process that modulates the frequency, rate or extent of rhodopsin-mediated signaling.
3 P21457 (/TAS) P43080 (/TAS) P43080 (/TAS)
Positive regulation of cGMP biosynthetic process GO:0030828
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of cGMP.
3 D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA)
Semicircular canal morphogenesis GO:0048752
The process in which the anatomical structures of the semicircular canals are generated and organized.
3 F1R8V7 (/IMP) F1R8V7 (/IMP) Q804C0 (/IMP)
Semicircular canal development GO:0060872
The progression of the semicircular canal from its initial formation to the mature structure.
3 F1R8V7 (/IGI) F1R8V7 (/IGI) Q804C0 (/IGI)
Cellular response to calcium ion GO:0071277
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
3 P46065 (/IDA) P46065 (/IDA) Q09711 (/IDA)
Regulation of systemic arterial blood pressure GO:0003073
The process that modulates the force with which blood travels through the systemic arterial circulatory system. The process is controlled by a balance of processes that increase pressure and decrease pressure.
2 Q91X97 (/IMP) Q91X97 (/IMP)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
2 P43080 (/NAS) P43080 (/NAS)
Chemical synaptic transmission GO:0007268
The vesicular release of classical neurotransmitter molecules from a neuron, across a chemical synapse, the subsequent activation of neurotransmitter receptors of a target cell (neuron, muscle, or secretory cell) and the effects of this activation on the postsynaptic membrane potential and ionic composition of the postsynaptic cytosol. This process encompasses both spontaneous and evoked release of neurotransmitter and all parts of synaptic vesicle exocytosis. Evoked transmission starts with the arrival of an action potential at the presynapse.
2 P37236 (/IMP) Q9VWX8 (/IMP)
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
2 P62762 (/TAS) Q9UM19 (/TAS)
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
2 P84076 (/IEP) P84076 (/IEP)
Neuromuscular junction development GO:0007528
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of a neuromuscular junction.
2 P37236 (/IMP) Q9VWX8 (/IMP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
2 P46065 (/ISS) P46065 (/ISS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
2 P43080 (/TAS) P43080 (/TAS)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
2 P43081 (/IMP) P43081 (/IMP)
Phototransduction GO:0007602
The sequence of reactions within a cell required to convert absorbed photons into a molecular signal.
2 P46065 (/ISS) P46065 (/ISS)
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
2 Q06389 (/IMP) Q06389 (/IMP)
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
2 Q06389 (/IPI) Q06389 (/IPI)
Positive regulation of phospholipase activity GO:0010518
Any process that increases the frequency, rate or extent of phospholipase activity, the hydrolysis of a phospholipid.
2 P84076 (/IDA) P84076 (/IDA)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 P84076 (/IEP) P84076 (/IEP)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
2 P84076 (/IEP) P84076 (/IEP)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
2 Q91X97 (/IMP) Q91X97 (/IMP)
Regulation of guanylate cyclase activity GO:0031282
Any process that modulates the frequency, rate or extent of guanylate cyclase activity.
2 P43081 (/IGI) P43081 (/IGI)
Regulation of guanylate cyclase activity GO:0031282
Any process that modulates the frequency, rate or extent of guanylate cyclase activity.
2 P46065 (/ISS) P46065 (/ISS)
Negative regulation of guanylate cyclase activity GO:0031283
Any process that stops, prevents, or reduces the frequency, rate or extent of guanylate cyclase activity.
2 P84076 (/IDA) P84076 (/IDA)
Activation of phospholipase D activity GO:0031584
Any process that initiates the activity of inactive phospholipase D.
2 P84076 (/IDA) P84076 (/IDA)
Cone photoresponse recovery GO:0036368
The processes required for a cone photoreceptor to recover, following light activation, so that it can respond to a subsequent light stimulus. Cone recovery requires the shutoff of active participants in the phototransduction cascade, including the visual pigment and downstream signal transducers.
2 I3ITF4 (/IMP) Q1LUD3 (/IMP)
Positive regulation of adenylate cyclase activity GO:0045762
Any process that activates or increases the frequency, rate or extent of adenylate cyclase activity.
2 P84076 (/IDA) P84076 (/IDA)
Positive regulation of exocytosis GO:0045921
Any process that activates or increases the frequency, rate or extent of exocytosis.
2 P62168 (/IDA) P62761 (/IDA)
Inner ear development GO:0048839
The process whose specific outcome is the progression of the inner ear over time, from its formation to the mature structure.
2 P84075 (/IDA) P84075 (/IDA)
Regulation of axon extension involved in axon guidance GO:0048841
Any process that modulates the frequency, rate or extent of axon extension involved in axon guidance.
2 Q6AXL4 (/IGI) Q6AXL4 (/IGI)
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
2 P84076 (/IEP) P84076 (/IEP)
Cellular response to electrical stimulus GO:0071257
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electrical stimulus.
2 P84076 (/IEP) P84076 (/IEP)
Positive regulation of protein targeting to membrane GO:0090314
Any process that increases the frequency, rate or extent of the process of directing proteins towards a membrane, usually using signals contained within the protein.
2 P84076 (/IDA) P84076 (/IDA)
Response to ketamine GO:1901986
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a ketamine stimulus.
2 P84076 (/IEP) P84076 (/IEP)
Response to L-glutamate GO:1902065
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an L-glutamate stimulus.
2 P84076 (/IEP) P84076 (/IEP)
Cellular response to monosodium glutamate GO:1904009
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a monosodium glutamate stimulus.
2 P84076 (/IDA) P84076 (/IDA)
Response to Aroclor 1254 GO:1904010
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an Aroclor 1254 stimulus.
2 P84076 (/IEP) P84076 (/IEP)
Chemotaxis GO:0006935
The directed movement of a motile cell or organism, or the directed growth of a cell guided by a specific chemical concentration gradient. Movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis).
1 P36608 (/IMP)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
1 P37236 (/IMP)
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
1 Q9VWX8 (/NAS)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 G3V6G4 (/IDA)
Chemosensory behavior GO:0007635
Behavior that is dependent upon the sensation of chemicals.
1 P36608 (/IMP)
Response to alkaline pH GO:0010446
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a pH stimulus with pH > 7. pH is a measure of the acidity or basicity of an aqueous solution.
1 P36608 (/IMP)
Negative regulation of induction of conjugation with cellular fusion GO:0010515
Any process that stops, prevents, or reduces the frequency or rate of initiation of conjugation with cellular fusion.
1 Q09711 (/IMP)
Regulation of neuron projection development GO:0010975
Any process that modulates the rate, frequency or extent of neuron projection development. Neuron projection development is the process whose specific outcome is the progression of a neuron projection over time, from its formation to the mature structure. A neuron projection is any process extending from a neural cell, such as axons or dendrites (collectively called neurites).
1 P62168 (/IMP)
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
1 P62762 (/TAS)
Sorocarp development GO:0030587
The process whose specific outcome is the progression of the sorocarp over time, from its formation to the mature structure. The process begins with the aggregation of individual cells and ends with the mature sorocarp. The sorocarp is a structure containing a spore-bearing sorus that sits on top of a stalk. An example of this process is found in Dictyostelium discoideum.
1 Q75K28 (/IMP)
Endocrine pancreas development GO:0031018
The process whose specific outcome is the progression of the endocrine pancreas over time, from its formation to the mature structure. The endocrine pancreas is made up of islet cells that produce insulin, glucagon and somatostatin.
1 E9QF94 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q4WLA4 (/IMP)
Positive regulation of insulin secretion involved in cellular response to glucose stimulus GO:0035774
Any process that increases the frequency, rate or extent of the regulated release of insulin that contributes to the response of a cell to glucose.
1 P62761 (/IDA)
Positive regulation of cAMP-mediated signaling GO:0043950
Any process which activates, maintains or increases the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
1 Q09711 (/IMP)
Negative regulation of insulin secretion GO:0046676
Any process that stops, prevents, or reduces the frequency, rate or extent of the regulated release of insulin.
1 P62761 (/IMP)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
1 Q9VWX8 (/IGI)
Regulation of neurotransmitter secretion GO:0046928
Any process that modulates the frequency, rate or extent of the regulated release of a neurotransmitter from a cell.
1 P37236 (/ISS)
Phosphatidylinositol-mediated signaling GO:0048015
A series of molecular signals in which a cell uses a phosphatidylinositol-mediated signaling to convert a signal into a response. Phosphatidylinositols include phosphatidylinositol (PtdIns) and its phosphorylated derivatives.
1 P62168 (/IDA)
Positive regulation of synaptic transmission GO:0050806
Any process that activates or increases the frequency, rate or extent of synaptic transmission, the process of communication from a neuron to a target (neuron, muscle, or secretory cell) across a synapse.
1 Q8BNY6 (/TAS)
Negative regulation of calcium ion import GO:0090281
Any process that decreases the rate, frequency, or extent of the directed movement of calcium ions into a cell or organelle.
1 Q09711 (/IMP)

There are 30 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Photoreceptor outer segment GO:0001750
The outer segment of a vertebrate photoreceptor that contains discs of photoreceptive membranes.
5 D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA) P43081 (/IDA) P43081 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P62168 (/IDA) P62761 (/IDA) Q09711 (/IDA) Q5PQN0 (/IDA) Q5PQN0 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P37235 (/IDA) P37235 (/IDA) P61601 (/IDA) P61601 (/IDA) P62166 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
5 P62748 (/ISO) P62748 (/ISO) Q8BNY6 (/ISO) Q91X97 (/ISO) Q91X97 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 A0A024R8B2 (/IDA) P62166 (/IDA) P62168 (/IDA) Q09711 (/IDA)
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
4 D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA) P62761 (/IDA)
Photoreceptor inner segment GO:0001917
The inner segment of a vertebrate photoreceptor containing mitochondria, ribosomes and membranes where opsin molecules are assembled and passed to be part of the outer segment discs.
3 D3ZEU1 (/IDA) D3ZII9 (/IDA) D3ZII9 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
3 P61601 (/IDA) P61601 (/IDA) Q9UM19 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
3 Q8BGZ1 (/ISO) Q91X97 (/ISO) Q91X97 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
3 P62166 (/IDA) Q09711 (/IDA) Q4WLA4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 P21457 (/TAS) P61601 (/TAS) P61601 (/TAS)
Axon GO:0030424
The long process of a neuron that conducts nerve impulses, usually away from the cell body to the terminals and varicosities, which are sites of storage and release of neurotransmitter.
3 P84076 (/IDA) P84076 (/IDA) Q8BNY6 (/IDA)
Golgi membrane GO:0000139
The lipid bilayer surrounding any of the compartments of the Golgi apparatus.
2 Q06389 (/IDA) Q06389 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
2 P61601 (/NAS) P61601 (/NAS)
Clathrin coat of trans-Golgi network vesicle GO:0030130
A clathrin coat found on a vesicle of the trans-Golgi network.
2 P61601 (/NAS) P61601 (/NAS)
Dendrite GO:0030425
A neuron projection that has a short, tapering, often branched, morphology, receives and integrates signals from other neurons or from sensory stimuli, and conducts a nerve impulse towards the axon or the cell body. In most neurons, the impulse is conveyed from dendrites to axon via the cell body, but in some types of unipolar neuron, the impulse does not travel via the cell body.
2 G3V6G4 (/IDA) Q8BNY6 (/IDA)
Dendrite membrane GO:0032590
The portion of the plasma membrane surrounding a dendrite.
2 P84076 (/IDA) P84076 (/IDA)
Neuronal cell body membrane GO:0032809
The plasma membrane of a neuron cell body - excludes the plasma membrane of cell projections such as axons and dendrites.
2 P84076 (/IDA) P84076 (/IDA)
Dendrite cytoplasm GO:0032839
All of the contents of a dendrite, excluding the surrounding plasma membrane.
2 P84076 (/IDA) P84076 (/IDA)
Perikaryon GO:0043204
The portion of the cell soma (neuronal cell body) that excludes the nucleus.
2 P84076 (/IDA) P84076 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
2 A0A024R8B2 (/IDA) P62166 (/IDA)
Dendritic spine head GO:0044327
Distal part of the dendritic spine, that carries the post-synaptic density.
2 P84076 (/IDA) P84076 (/IDA)
Photoreceptor disc membrane GO:0097381
Ovally-shaped membranous stack located inside the photoreceptor outer segment, and containing densely packed molecules of the photoreceptor protein rhodopsin that traverse the lipid bilayer. Disc membranes are apparently derived from the plasma membrane in the region of the cilium that connects the photoreceptor outer segment to the inner segment.
2 P43080 (/TAS) P43080 (/TAS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q09711 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q8BNY6 (/ISO)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
1 Q8BNY6 (/ISO)
Synaptic vesicle GO:0008021
A secretory organelle, typically 50 nm in diameter, of presynaptic nerve terminals; accumulates in high concentrations of neurotransmitters and secretes these into the synaptic cleft by fusion with the 'active zone' of the presynaptic plasma membrane.
1 Q9VWX8 (/NAS)
Cytoplasmic vesicle GO:0031410
A vesicle found in the cytoplasm of a cell.
1 P62168 (/IDA)
Neuronal cell body GO:0043025
The portion of a neuron that includes the nucleus, but excludes cell projections such as axons and dendrites.
1 P36608 (/IDA)
Intracellular membrane-bounded organelle GO:0043231
Organized structure of distinctive morphology and function, bounded by a single or double lipid bilayer membrane and occurring within the cell. Includes the nucleus, mitochondria, plastids, vacuoles, and vesicles. Excludes the plasma membrane.
1 Q8BNY6 (/ISO)