The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 32614: N-terminal EF-hand calcium-binding protein 2
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 4 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q7Z6G3 (/IPI) |
|
A2A adenosine receptor binding GO:0031687
Interacting selectively and non-covalently with an A2A adenosine receptor.
|
1 | Q7Z6G3 (/IDA) |
|
Type 5 metabotropic glutamate receptor binding GO:0031802
Interacting selectively and non-covalently with a type 5 metabotropic glutamate receptor.
|
1 | Q7Z6G3 (/IDA) |
|
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
|
1 | Q91ZP9 (/ISO) |
There are 6 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Calcium-mediated signaling GO:0019722
Any intracellular signal transduction in which the signal is passed on within the cell via calcium ions.
|
2 | F1LQY6 (/NAS) Q9ESB4 (/NAS) |
|
Positive regulation of adenosine receptor signaling pathway GO:0060168
Any process that activates or increases the frequency, rate or extent of the adenosine receptor signaling pathway. The adenosine receptor pathway is the series of molecular signals generated as a consequence of an adenosine receptor binding to one of its physiological ligands.
|
1 | Q7Z6G3 (/IDA) |
|
Positive regulation of ERK1 and ERK2 cascade GO:0070374
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
1 | Q7Z6G3 (/IDA) |
|
Positive regulation of glutamate receptor signaling pathway GO:1900451
Any process that activates or increases the frequency, rate or extent of glutamate receptor signaling pathway.
|
1 | Q7Z6G3 (/IDA) |
|
Negative regulation of G-protein coupled receptor internalization GO:1904021
Any process that stops, prevents or reduces the frequency, rate or extent of G-protein coupled receptor internalization.
|
1 | Q7Z6G3 (/IDA) |
|
Positive regulation of protein localization to membrane GO:1905477
Any process that activates or increases the frequency, rate or extent of protein localization to membrane.
|
1 | Q7Z6G3 (/IDA) |
There are 2 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
2 | F1LQY6 (/IDA) Q9ESB4 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q7Z6G3 (/IDA) |