The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
EF-hand
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 32250: Calcineurin subunit B type 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 Q9UU93 (/ISM)
Calcium ion binding GO:0005509
Interacting selectively and non-covalently with calcium ions (Ca2+).
1 P25296 (/ISS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P25296 (/IPI)
Calcium-dependent protein serine/threonine phosphatase regulator activity GO:0008597
Modulation of the activity of the enzyme calcium-dependent protein serine/threonine phosphatase.
1 Q9UU93 (/IDA)

There are 17 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
3 A0A1D8PP58 (/IMP) B9WI58 (/IMP) Q6FLU4 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
3 B9WI58 (/IMP) P25296 (/IMP) Q6FLU4 (/IMP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
3 A0A1D8PP58 (/IMP) B9WI58 (/IMP) Q6FLU4 (/IMP)
Adaptation of signaling pathway by response to pheromone involved in conjugation with cellular fusion GO:0000754
In organisms that undergo conjugation with cellular fusion, the process resulting in desensitization following exposure to pheromone stimulus that act to down-regulate further stimulation or block initial conjugation responses. An example of this is the adaptation to pheromone during conjugation with cellular fusion in Saccharomyces cerevisiae.
1 P25296 (/IMP)
MRNA catabolic process GO:0006402
The chemical reactions and pathways resulting in the breakdown of mRNA, messenger RNA, which is responsible for carrying the coded genetic 'message', transcribed from DNA, to sites of protein assembly at the ribosomes.
1 Q6FLU4 (/IMP)
Cellular ion homeostasis GO:0006873
Any process involved in the maintenance of an internal steady state of ions at the level of a cell.
1 P25296 (/IMP)
Cellular calcium ion homeostasis GO:0006874
Any process involved in the maintenance of an internal steady state of calcium ions at the level of a cell.
1 A0A1D8PP58 (/IMP)
Regulation of signal transduction GO:0009966
Any process that modulates the frequency, rate or extent of signal transduction.
1 Q9UU93 (/IC)
Cellular cation homeostasis GO:0030003
Any process involved in the maintenance of an internal steady state of cations at the level of a cell.
1 B9WI58 (/IMP)
Hyphal growth GO:0030448
Growth of fungi as threadlike, tubular structures that may contain multiple nuclei and may or may not be divided internally by septa, or cross-walls.
1 A0A1D8PP58 (/IMP)
Fungal-type cell wall organization GO:0031505
A process that is carried out at the cellular level which results in the assembly, arrangement of constituent parts, or disassembly of the fungal-type cell wall.
1 P25296 (/IGI)
Response to endoplasmic reticulum stress GO:0034976
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stress acting at the endoplasmic reticulum. ER stress usually results from the accumulation of unfolded or misfolded proteins in the ER lumen.
1 Q6FLU4 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 B9WI58 (/IMP)
Growth of symbiont in host GO:0044117
The increase in size or mass of an organism, occurring within the cells or tissues of the host organism. This may (but not necessarily) include a filamentous growth form, and also can include secretion of proteases and lipases to break down host tissue. The host is defined as the larger of the organisms involved in a symbiotic interaction.
1 Q6FLU4 (/IMP)
Response to calcium ion GO:0051592
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a calcium ion stimulus.
1 A0A1D8PP58 (/IMP)
Calcium ion homeostasis GO:0055074
Any process involved in the maintenance of an internal steady state of calcium ions within an organism or cell.
1 Q6FLU4 (/IMP)
Cellular heat acclimation GO:0070370
Any process that increases heat tolerance of a cell in response to high temperatures.
1 Q6FLU4 (/IMP)

There are 8 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q9UU93 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9UU93 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q9UU93 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q9UU93 (/IDA)
Calcineurin complex GO:0005955
A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
1 P25296 (/IDA)
Calcineurin complex GO:0005955
A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
1 P25296 (/IPI)
Calcineurin complex GO:0005955
A heterodimeric calcium ion and calmodulin dependent protein phosphatase composed of catalytic and regulatory subunits; the regulatory subunit is very similar in sequence to calmodulin.
1 Q9UU93 (/ISO)
Cell division site GO:0032153
The eventual plane of cell division (also known as cell cleavage or cytokinesis) in a dividing cell. In Eukaryotes, the cleavage apparatus, composed of septin structures and the actomyosin contractile ring, forms along this plane, and the mitotic, or meiotic, spindle is aligned perpendicular to the division plane. In bacteria, the cell division site is generally located at mid-cell and is the site at which the cytoskeletal structure, the Z-ring, assembles.
1 Q9UU93 (/IDA)