The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"EF-hand
".
FunFam 14551: Epidermal growth factor receptor substrate 15-like...
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 3 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
2 | Q60902 (/IPI) Q9UBC2 (/IPI) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | Q9UBC2 (/IDA) |
|
Cadherin binding GO:0045296
Interacting selectively and non-covalently with cadherin, a type I membrane protein involved in cell adhesion.
|
1 | Q60902 (/ISO) |
There are 8 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Receptor-mediated endocytosis GO:0006898
An endocytosis process in which cell surface receptors ensure specificity of transport. A specific receptor on the cell surface binds tightly to the extracellular macromolecule (the ligand) that it recognizes; the plasma-membrane region containing the receptor-ligand complex then undergoes endocytosis, forming a transport vesicle containing the receptor-ligand complex and excluding most other plasma-membrane proteins. Receptor-mediated endocytosis generally occurs via clathrin-coated pits and vesicles.
|
5 | E3CTP7 (/NAS) Q8MMD2 (/NAS) Q8MMD3 (/NAS) Q8WQ61 (/NAS) Q9W111 (/NAS) |
|
Neurotransmitter secretion GO:0007269
The regulated release of neurotransmitter from the presynapse into the synaptic cleft via calcium regualated exocytosis during synaptic transmission.
|
5 | E3CTP7 (/NAS) Q8MMD2 (/NAS) Q8MMD3 (/NAS) Q8WQ61 (/NAS) Q9W111 (/NAS) |
|
Regulation of synaptic growth at neuromuscular junction GO:0008582
Any process that modulates the frequency, rate or extent of synaptic growth at neuromuscular junctions.
|
5 | E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP) |
|
Negative regulation of Notch signaling pathway GO:0045746
Any process that stops, prevents, or reduces the frequency, rate or extent of the Notch signaling pathway.
|
5 | E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP) |
|
Synaptic vesicle endocytosis GO:0048488
Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
|
5 | E3CTP7 (/IMP) Q8MMD2 (/IMP) Q8MMD3 (/IMP) Q8WQ61 (/IMP) Q9W111 (/IMP) |
|
Synaptic vesicle endocytosis GO:0048488
Clathrin-mediated endocytosis of presynaptic membrane that recycles synaptic vesicle membrane and its components following synaptic vesicle exocytosis. This process starts with coating of the membrane with adaptor proteins and clathrin prior to invagination and ends when uncoating has finished.
|
5 | E3CTP7 (/TAS) Q8MMD2 (/TAS) Q8MMD3 (/TAS) Q8WQ61 (/TAS) Q9W111 (/TAS) |
|
Negative regulation of epidermal growth factor receptor signaling pathway GO:0042059
Any process that stops, prevents, or reduces the frequency, rate or extent of epidermal growth factor receptor signaling pathway activity.
|
1 | Q9UBC2 (/TAS) |
|
Membrane organization GO:0061024
A process which results in the assembly, arrangement of constituent parts, or disassembly of a membrane. A membrane is a double layer of lipid molecules that encloses all cells, and, in eukaryotes, many organelles; may be a single or double lipid bilayer; also includes associated proteins.
|
1 | Q9UBC2 (/TAS) |
There are 7 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
5 | E3CTP7 (/IDA) Q8MMD2 (/IDA) Q8MMD3 (/IDA) Q8WQ61 (/IDA) Q9W111 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | Q9UBC2 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q9UBC2 (/TAS) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q9UBC2 (/IDA) |
|
Membrane GO:0016020
A lipid bilayer along with all the proteins and protein complexes embedded in it an attached to it.
|
1 | Q60902 (/ISO) |
|
Clathrin coat of coated pit GO:0030132
The coat found on coated pits and the coated vesicles derived from coated pits; comprises clathrin and the AP-2 adaptor complex.
|
1 | Q60902 (/IDA) |
|
Presynaptic endocytic zone cytoplasmic component GO:0098834
The cytoplasmic component of the presynaptic endocytic zone.
|
1 | E3CTP7 (/IDA) |