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CATH Superfamily 1.10.230.10

Cytochrome P450-Terp, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450-Terp, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 342: Citrate synthase 2

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-methylcitrate synthase. [EC: 2.3.3.5]
Propanoyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3- tricarboxylate + CoA.
  • The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA.
  • The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1.
  • Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate.
  • Formerly EC 4.1.3.31.
 105 A0A029L3L2 A0A058YP11 A0A069PAV0 A0A069XFF8 A0A070SBU8 A0A070UIH4 A0A074J8B2 A0A080FDL5 A0A0C6PDA7 A0A0D6HCM5
(95 more...)
Citrate synthase (unknown stereospecificity). [EC: 2.3.3.16]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).
 57 A0A029L3L2 A0A069XFF8 A0A070SBU8 A0A070UIH4 A0A074J8B2 A0A080FDL5 A0A0D6HCM5 A0A0E0TTY2 A0A0E1LTS0 A0A0F6AXI0
(47 more...)
Citrate (Si)-synthase. [EC: 2.3.3.1]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.
  • Formerly EC 4.1.3.7.
  • Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16.
 4 A0A058YP11 A0A0C6PDA7 A0A1M9DIV3 A0A1N7RQL1
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