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CATH Superfamily 1.10.230.10

Cytochrome P450-Terp, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450-Terp, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2352: Probable citrate synthase, mitochondrial

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Citrate (Si)-synthase. [EC: 2.3.3.1]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.
  • Formerly EC 4.1.3.7.
  • Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16.
 118 A0A024RB75 A0A062XY76 A0A085L2Y8 A0A098S7C5 A0A0B5BBC9 A0A0B5BDX9 A0A0B5FDD5 A0A0B8S099 A0A0C1I8T0 A0A0C1LJP4
(108 more...)
Citrate synthase (unknown stereospecificity). [EC: 2.3.3.16]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).
 49 A0A0B0DXK0 A0A0J5SEH0 A0A0L8VUH1 A0A1D8NGX1 A0A1J5TMB4 A4H9H8 A4HXU4 A6ZTI7 B0YD89 B3LU77
(39 more...)
2-methylcitrate synthase. [EC: 2.3.3.5]
Propanoyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3- tricarboxylate + CoA.
  • The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA.
  • The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1.
  • Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate.
  • Formerly EC 4.1.3.31.
 10 A0A0J5SEH0 A0A1D8NGX1 B0YD89 C7C435 C7C436 E9QUP9 Q50I20 Q6C793 Q9TEM3 W7LKQ3
Poly(A)-specific ribonuclease. [EC: 3.1.13.4]
Exonucleolytic cleavage of poly(A) to 5'-AMP.
  • Cleaves poly(A) in either the single- or double-stranded form.
 3 A0A091D300 M7B1U4 T0MEV1
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