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CATH Superfamily 1.10.230.10

Cytochrome P450-Terp, domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Cytochrome P450-Terp, domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 2296: Citrate synthase I gltA1

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
2-methylcitrate synthase. [EC: 2.3.3.5]
Propanoyl-CoA + H(2)O + oxaloacetate = (2S,3S)-2-hydroxybutane-1,2,3- tricarboxylate + CoA.
  • The enzyme acts on acetyl-CoA, propanoyl-CoA, butanoyl-CoA and pentanoyl-CoA.
  • The relative rate of condensation of acetyl-CoA and oxaloacetate is 140% of that of propanoyl-CoA and oxaloacetate, but the enzyme is distinct from EC 2.3.3.1.
  • Oxaloacetate cannot be replaced by glyoxylate, pyruvate or 2-oxoglutarate.
  • Formerly EC 4.1.3.31.
 17 A0A045IMZ2 A0A0C7DHE0 A0A0G4DZ15 A0A0H3MC64 A0A0H3P2G4 A0A0K2HUA0 A0A0T9XZR0 A0A109SLX7 A0A120J0F5 A5U1H8
(7 more...)
Citrate synthase (unknown stereospecificity). [EC: 2.3.3.16]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • This entry has been included to accommodate those citrate synthases for which the stereospecificity with respect to C(2) of oxaloacetate has not been established (cf. EC 2.3.3.1 and EC 2.3.3.3).
 16 A0A045IMZ2 A0A0C7DHE0 A0A0G4DZ15 A0A0H3MC64 A0A0H3P2G4 A0A0K2HUA0 A0A109SLX7 A0A120J0F5 A5U1H8 F8M5S5
(6 more...)
Citrate (Si)-synthase. [EC: 2.3.3.1]
Acetyl-CoA + H(2)O + oxaloacetate = citrate + CoA.
  • The stereospecificity of this enzyme is opposite to that of EC 2.3.3.3, which is found in some anaerobes.
  • Formerly EC 4.1.3.7.
  • Citrate synthase for which the stereospecificity with respect to C(2) of oxaloacetate has not been established are included in EC 2.3.3.16.
 1 A0A0T9XZR0
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