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CATH Superfamily 1.10.150.240

Putative phosphatase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Putative phosphatase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 7285: Bifunctional phosphonoacetaldehyde hydrolase/amino...

There are 2 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphonoacetaldehyde hydrolase. [EC: 3.11.1.1]
Phosphonoacetaldehyde + H(2)O = acetaldehyde + phosphate.
  • This enzyme destabilizes the C-P bond, by forming an imine between one of its lysine residues and the carbonyl group of the substrate, thus allowing this, normally stable, bond to be broken.
  • The mechanism is similar to that used by EC 4.1.2.13 to break a C-C bond.
 1831 A0A009G8B2 A0A009HBV0 A0A009HPP3 A0A009KLI2 A0A009M7E7 A0A009QLB1 A0A009QT92 A0A009SMK1 A0A009T3Z2 A0A010G586
(1821 more...)
2-aminoethylphosphonate--pyruvate transaminase. [EC: 2.6.1.37]
(2-aminoethyl)phosphonate + pyruvate = 2-phosphonoacetaldehyde + L-alanine.
  • 2-aminoethylarsonate can replace 2-aminoethylphosphonate as a substrate.
 14 A0A069AED3 A0A125V906 A0A160WIH8 A0A160WIW4 A0A160XCB7 A0A160YFB6 A0A171CLY8 D5Q8Q0 D5RVA5 Q183T0
(4 more...)