View in Gene3D

CATH Superfamily 1.10.150.110

DNA polymerase beta, N-terminal domain-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
DNA polymerase beta, N-terminal domain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 1051: Mutant DNA polymerase beta

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
DNA-directed DNA polymerase. [EC: 2.7.7.7]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Requires a primer which may be DNA or RNA.
  • See also EC 2.7.7.49.
 54 A0A061IPE9 A0A088RJ04 A0A0B2NZB6 A0A0B7MTL5 A0A0L1HZ02 A0A0U2SWJ7 A0A140E0M9 A0A165XF78 A0A1E1EVX4 A0A1E1IQB1
(44 more...)
DNA nucleotidylexotransferase. [EC: 2.7.7.31]
Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
  • Catalyzes template-independent extension of the 3'-end of a DNA strand by one nucleotide at a time.
  • Cannot initiate a chain de novo.
  • Nucleoside may be ribo- or deoxyribo-.
 14 A0A061IE05 A0A1L8FJ83 A4PCD4 B7QK41 E0VPG0 K0KG88 O02789 O57486 P04053 P06526
(4 more...)
Histone-lysine N-methyltransferase. [EC: 2.1.1.43]
S-adenosyl-L-methionine + L-lysine-[histone] = S-adenosyl-L-homocysteine + N(6)-methyl-L-lysine-[histone].
    		 2 A0A183XHH3 A0A1I8EKA5
    Crossover junction endodeoxyribonuclease. [EC: 3.1.22.4]
    Endonucleolytic cleavage at a junction such as a reciprocal single- stranded crossover between two homologous DNA duplexes (Holliday junction).
    • The enzyme from Saccharomyces cerevisiae has no endonuclease or exonuclease activity on single-stranded or double-stranded DNA molecules that do not contain Holliday junctions.
    		 1 Q9V3T1