The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Tetraspanin
".
FunFam 2030: CD63 antigen
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 1 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P08962 (/IPI) |
There are 18 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Positive regulation of receptor internalization GO:0002092
Any process that activates or increases the frequency, rate or extent of receptor internalization.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Endosome to melanosome transport GO:0035646
The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Pigment granule maturation GO:0048757
Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Regulation of vascular endothelial growth factor signaling pathway GO:1900746
Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Positive regulation of receptor internalization GO:0002092
Any process that activates or increases the frequency, rate or extent of receptor internalization.
|
1 | P08962 (/IMP) |
|
Platelet degranulation GO:0002576
The regulated exocytosis of secretory granules containing preformed mediators such as histamine and serotonin by a platelet.
|
1 | P08962 (/TAS) |
|
Cell-matrix adhesion GO:0007160
The binding of a cell to the extracellular matrix via adhesion molecules.
|
1 | P08962 (/IMP) |
|
Cell migration GO:0016477
The controlled self-propelled movement of a cell from one site to a destination guided by molecular cues. Cell migration is a central process in the development and maintenance of multicellular organisms.
|
1 | P08962 (/IMP) |
|
Cellular protein localization GO:0034613
Any process in which a protein is transported to, and/or maintained in, a specific location at the level of a cell. Localization at the cellular level encompasses movement within the cell, from within the cell to the cell surface, or from one location to another at the surface of a cell.
|
1 | P08962 (/IDA) |
|
Endosome to melanosome transport GO:0035646
The directed movement of substances from endosomes to the melanosome, a specialised lysosome-related organelle.
|
1 | P08962 (/IMP) |
|
Neutrophil degranulation GO:0043312
The regulated exocytosis of secretory granules containing preformed mediators such as proteases, lipases, and inflammatory mediators by a neutrophil.
|
1 | P08962 (/TAS) |
|
Pigment granule maturation GO:0048757
Steps required to form a membrane-bounded organelle into a pigment granule containing pigment. Maturation is a developmental process, independent of morphogenetic (shape) change, that is required for a cell or structure to attain its fully functional state.
|
1 | P08962 (/IMP) |
|
Regulation of vascular endothelial growth factor signaling pathway GO:1900746
Any process that modulates the frequency, rate or extent of vascular endothelial growth factor signaling pathway.
|
1 | P08962 (/IMP) |
|
Regulation of rubidium ion transport GO:2000680
Any process that modulates the frequency, rate or extent of rubidium ion transport.
|
1 | P08962 (/IDA) |
|
Positive regulation of integrin-mediated signaling pathway GO:2001046
Any process that activates or increases the frequency, rate or extent of integrin-mediated signaling pathway.
|
1 | P08962 (/IMP) |
There are 19 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Multivesicular body, internal vesicle GO:0097487
A membrane-bounded vesicle wholly contained within a multivesicular body.
|
3 | Q28709 (/ISS) Q76B49 (/ISS) Q9XSK2 (/ISS) |
|
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
|
1 | P08962 (/IDA) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | P08962 (/IDA) |
|
Lysosomal membrane GO:0005765
The lipid bilayer surrounding the lysosome and separating its contents from the cell cytoplasm.
|
1 | P08962 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | P08962 (/TAS) |
|
Integral component of plasma membrane GO:0005887
The component of the plasma membrane consisting of the gene products and protein complexes having at least some part of their peptide sequence embedded in the hydrophobic region of the membrane.
|
1 | P08962 (/TAS) |
|
Cell surface GO:0009986
The external part of the cell wall and/or plasma membrane.
|
1 | P08962 (/IDA) |
|
Endosome membrane GO:0010008
The lipid bilayer surrounding an endosome.
|
1 | P08962 (/IDA) |
|
Platelet dense granule membrane GO:0031088
The lipid bilayer surrounding the platelet dense granule.
|
1 | P08962 (/TAS) |
|
Intrinsic component of plasma membrane GO:0031226
The component of the plasma membrane consisting of the gene products and protein complexes having either part of their peptide sequence embedded in the hydrophobic region of the membrane or some other covalently attached group such as a GPI anchor that is similarly embedded in the membrane.
|
1 | P08962 (/IDA) |
|
Late endosome membrane GO:0031902
The lipid bilayer surrounding a late endosome.
|
1 | P08962 (/IDA) |
|
Endosome lumen GO:0031904
The volume enclosed by the membrane of an endosome.
|
1 | P08962 (/IDA) |
|
Multivesicular body membrane GO:0032585
The lipid bilayer surrounding a multivesicular body.
|
1 | P08962 (/IDA) |
|
Azurophil granule membrane GO:0035577
The lipid bilayer surrounding an azurophil granule, a primary lysosomal granule found in neutrophil granulocytes that contains a wide range of hydrolytic enzymes and is released into the extracellular fluid.
|
1 | P08962 (/TAS) |
|
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
|
1 | P08962 (/IDA) |
|
Multivesicular body, internal vesicle GO:0097487
A membrane-bounded vesicle wholly contained within a multivesicular body.
|
1 | P08962 (/IDA) |