The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Di-copper center containing domain from catechol oxidase
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 2225: Pro-phenol oxidase subunit 1

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 11 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
25 O44249 (/ISS) P02241 (/ISS) P02242 (/ISS) P14750 (/ISS) P80476 (/ISS) Q25519 (/ISS) Q86N89 (/ISS) Q86N90 (/ISS) Q86N91 (/ISS) Q86N92 (/ISS)
(15 more)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
25 O44249 (/ISS) P02241 (/ISS) P02242 (/ISS) P14750 (/ISS) P80476 (/ISS) Q25519 (/ISS) Q86N89 (/ISS) Q86N90 (/ISS) Q86N91 (/ISS) Q86N92 (/ISS)
(15 more)
Monophenol monooxygenase activity GO:0004503
Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
4 O44249 (/TAS) Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS)
L-DOPA monooxygenase activity GO:0036263
Catalysis of the reaction: L-DOPA + O2 = ? + H2O. This reaction catalyzes the oxygenation of the dopamine precursor L-DOPA, to the corresponding o-quinone.
3 Q7K2W6 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA)
Dopamine monooxygenase activity GO:0036264
Catalysis of the reaction: dopamine + O2 = ? + H2O. This reaction catalyzes the oxygenation of dopamine to the corresponding o-quinone.
3 Q7K2W6 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA)
Catechol oxidase activity GO:0004097
Catalysis of the reaction: 2 catechol + O2 = 2 1,2-benzoquinone + 2 H2O.
1 Q7K2W6 (/IDA)
Monophenol monooxygenase activity GO:0004503
Catalysis of the reaction: L-tyrosine + L-DOPA + O2 = L-DOPA + DOPAquinone + H2O.
1 Q7K2W6 (/IDA)
Oxygen transporter activity GO:0005344
Enables the directed movement of oxygen into, out of or within a cell, or between cells.
1 P04253 (/NAS)
Copper ion binding GO:0005507
Interacting selectively and non-covalently with copper (Cu) ions.
1 P04253 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 Q27598 (/IPI)
Chloride ion binding GO:0031404
Interacting selectively and non-covalently with chloride ions (Cl-).
1 P04253 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Melanin biosynthetic process from tyrosine GO:0006583
The chemical reactions and pathways resulting in the formation of melanin from other compounds, including tyrosine.
4 O44249 (/TAS) Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
3 Q25519 (/TAS) Q27451 (/TAS) Q27452 (/TAS)
Dopamine metabolic process GO:0042417
The chemical reactions and pathways involving dopamine, a catecholamine neurotransmitter and a metabolic precursor of noradrenaline and adrenaline.
3 Q7K2W6 (/IC) Q9V521 (/IC) Q9W1V6 (/IC)
Melanization defense response GO:0035006
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
2 Q7K2W6 (/IGI) Q9V521 (/IGI)
Melanization defense response GO:0035006
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
2 Q7K2W6 (/IMP) Q9V521 (/IMP)
Melanotic encapsulation of foreign target GO:0035011
Formation of a multilayered, melanized sheath of cells around a foreign invader.
2 Q9V521 (/IGI) Q9W1V6 (/IGI)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
2 Q7K2W6 (/IGI) Q9V521 (/IGI)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 Q7K2W6 (/IGI) Q9V521 (/IGI)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
2 Q7K2W6 (/IMP) Q9V521 (/IMP)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
1 O44249 (/NAS)
Motor neuron axon guidance GO:0008045
The process in which the migration of an axon growth cone of a motor neuron is directed to a specific target site in response to a combination of attractive and repulsive cues.
1 Q24388 (/IMP)
Response to wounding GO:0009611
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating damage to the organism.
1 Q7K2W6 (/IMP)
Oxygen transport GO:0015671
The directed movement of oxygen (O2) into, out of or within a cell, or between cells, by means of some agent such as a transporter or pore.
1 P04253 (/NAS)
Synaptic target inhibition GO:0016201
The process in which a neuronal cell in a multicellular organism recognizes chemorepellent signals that inhibit its growth toward the source.
1 Q24388 (/IMP)
Sleep GO:0030431
Any process in which an organism enters and maintains a periodic, readily reversible state of reduced awareness and metabolic activity. Usually accompanied by physical relaxation, the onset of sleep in humans and other mammals is marked by a change in the electrical activity of the brain.
1 Q7K2W6 (/IEP)
Melanization defense response GO:0035006
The blackening of the wounded area of the cuticle or the surface of invading pathogens, parasites or parasitoids, resulting from a proteolytic cascade leading to the de novo synthesis and deposition of melanin.
1 Q7K2W6 (/TAS)
Positive regulation of melanization defense response GO:0035008
Any process that increases the rate or extent of the melanization defense response during injury or invasion.
1 O44249 (/IDA)
Positive regulation of melanization defense response GO:0035008
Any process that increases the rate or extent of the melanization defense response during injury or invasion.
1 Q25519 (/NAS)
Scab formation GO:0035314
Formation of hardened covering (a scab) at a wound site. The scab has multiple functions including limiting blood loss, providing structural stability to the wound and guarding against infection.
1 Q7K2W6 (/IMP)
Wound healing GO:0042060
The series of events that restore integrity to a damaged tissue, following an injury.
1 Q7K2W6 (/IMP)
Hemolymph coagulation GO:0042381
Any process in which factors in the hemolymph (the invertebrate equivalent of vertebrate blood and lymph) precipitate into insoluble clots in order to prevent loss of body fluid, and at the same time prevent the movement of microbes. Hemolymph coagulation is also part of the invertebrate humoral immune response.
1 Q7K2W6 (/IMP)
Lateral inhibition GO:0046331
Signaling between cells of equivalent developmental potential that results in these cells adopting different developmental fates. An example is the suppression by cells with a particular fate of the adoption of the same fate by surrounding cells.
1 P11996 (/IMP)
Defense response to Gram-positive bacterium GO:0050830
Reactions triggered in response to the presence of a Gram-positive bacterium that act to protect the cell or organism.
1 Q7K2W6 (/IMP)
Protein oligomerization GO:0051259
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of component monomers; protein oligomers may be composed of different or identical monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P04253 (/TAS)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
9 O44249 (/IDA) Q25519 (/IDA) Q7K2W6 (/IDA) Q8IFJ8 (/IDA) Q8T115 (/IDA) Q95P07 (/IDA) Q95P08 (/IDA) Q9V521 (/IDA) Q9W1V6 (/IDA)
Larval serum protein complex GO:0005616
A multisubunit protein complex which, in Drosophila, is a heterohexamer of three subunits, alpha, beta and gamma. The complex is thought to store amino acids for synthesis of adult proteins.
4 P11995 (/IDA) P11996 (/IDA) P11997 (/IDA) Q24388 (/IDA)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
2 Q27451 (/TAS) Q27452 (/TAS)
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q8T116 (/ISS)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 P04253 (/IC)
Extracellular space GO:0005615
That part of a multicellular organism outside the cells proper, usually taken to be outside the plasma membranes, and occupied by fluid.
1 Q9V521 (/IDA)