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CATH Superfamily 1.10.1200.10

ACP-like

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
ACP-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 12529: 2,3-dihydro-2,3-dihydroxybenzoate synthetase

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Isochorismatase. [EC: 3.3.2.1]
Isochorismate + H(2)O = (2S,3S)-2,3-dihydroxy-2,3-dihydrobenzoate + pyruvate.
    		 514 A0A017IK07 A0A017IK07 A0A023YTC8 A0A023YTC8 A0A024KQR9 A0A024KQR9 A0A025CIB5 A0A025CIB5 A0A026RW97 A0A026RW97
    (504 more...)
    Enterobactin synthase. [EC: 6.3.2.14]
    6 ATP + 3 2,3-dihydroxybenzoate + 3 L-serine = enterobactin + 6 AMP + 6 diphosphate.
    • This enzyme complex catalyzes the conversion of three molecules each of 2,3-dihydroxybenzoate and L-serine to form the siderophore enterobactin.
    • In Escherichia coli the complex is formed by EntB (an aryl carrier protein that has to be activated by 4'-phosphopantetheine), EntD (a phosphopantetheinyl transferase that activates EntB), EntE (catalyzes the ATP-dependent condensation of 2,3-dihydroxybenzoate and holo-EntB to form the covalently arylated form of EntB), and EntF (a four domain protein that catalyzes the activation of L-serine by ATP, the condensation of the activated L-serine with the activated 2,3- dihydroxybenzoate, and the trimerization of three such moieties to a single enterobactin molecule).
    		 146 A0A024KQR9 A0A024KQR9 A0A029PSH9 A0A029PSH9 A0A064U576 A0A064U576 A0A069XH51 A0A069XH51 A0A070SSL0 A0A070SSL0
    (136 more...)
    (2,3-dihydroxybenzoyl)adenylate synthase. [EC: 2.7.7.58]
    ATP + 2,3-dihydroxybenzoate = diphosphate + (2,3- dihydroxybenzoyl)adenylate.
      		 2 I6HC67 I6HC67
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