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CATH Superfamily 1.10.1070.11

Phosphatidylinositol 3-/4-kinase, catalytic domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Phosphatidylinositol 3-/4-kinase, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1631: Phosphatidylinositol 3-kinase tor2, putative

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Non-specific serine/threonine protein kinase. [EC: 2.7.11.1]
ATP + a protein = ADP + a phosphoprotein.
  • This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date.
  • Formerly EC 2.7.1.37 and EC 2.7.1.70.
 28 A0A061IEK3 A0A061IH47 A0A061II58 A0A0A1TXZ3 A0A0A1UFZ7 A0A0B7FXR2 A0A178WN52 B0E886 B0ELI1 B8M8J5
(18 more...)
Phosphatidylinositol 3-kinase. [EC: 2.7.1.137]
ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 3-phosphate.
    		 5 A0A0F4YSL9 A0A0F8AZS2 A2R7T9 A3LYF1 C5P040
    1-phosphatidylinositol 4-kinase. [EC: 2.7.1.67]
    ATP + 1-phosphatidyl-1D-myo-inositol = ADP + 1-phosphatidyl-1D-myo- inositol 4-phosphate.
      		 2 P32600 W1QL64
      Ribonuclease P. [EC: 3.1.26.5]
      Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.
      • Essential for tRNA processing; generates 5'-termini of mature tRNA molecules.
      		 1 B0ELI1
      DNA-directed RNA polymerase. [EC: 2.7.7.6]
      Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).
      • Catalyzes DNA-template-directed extension of the 3'-end of an RNA strand by one nucleotide at a time.
      • Can initiate a chain de novo.
      • In eukaryotes three forms of the enzyme have been distinguished on the basis of sensitivity of alpha-amanitin, and the type of RNA synthesized.
      • See also EC 2.7.7.19 and EC 2.7.7.48.
      		 1 A0A0D2UH62
      DNA-directed DNA polymerase. [EC: 2.7.7.7]
      Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1).
      • Catalyzes DNA-template-directed extension of the 3'-end of a DNA strand by one nucleotide at a time.
      • Cannot initiate a chain de novo.
      • Requires a primer which may be DNA or RNA.
      • See also EC 2.7.7.49.
      		 1 G0QV49
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