View in Gene3D

CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
« Back to all FunFams

FunFam 6929: 6-phosphogluconate dehydrogenase YqeC

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Phosphogluconate dehydrogenase (NADP(+)-dependent, decarboxylating). [EC: 1.1.1.44]
6-phospho-D-gluconate + NADP(+) = D-ribulose 5-phosphate + CO(2) + NADPH.
  • The enzyme participates in the oxidative branch of the pentose phosphate pathway, whose main purpose is to produce NADPH and pentose for biosynthetic reactions.
  • Highly specific for NADP(+).
  • Cf. EC 1.1.1.343.
 144 A0A023DED9 A0A023P9L8 A0A076WAS9 A0A084IVS6 A0A0A3WQE8 A0A0B5R4M9 A0A0B5SJG9 A0A0B6A843 A0A0B6B006 A0A0B6BIL1
(134 more...)
3-hydroxyisobutyrate dehydrogenase. [EC: 1.1.1.31]
3-hydroxy-2-methylpropanoate + NAD(+) = 2-methyl-3-oxopropanoate + NADH.
    		 18 A0A0B6BIL1 A0A0E0W304 A0A0G8D9I2 A0A0U0ECN5 A0A154AVE6 B3Z4P1 B7JG62 C2MN77 C2TJ69 C2VW98
    (8 more...)
    Phosphogluconate dehydrogenase (NAD(+)-dependent, decarboxylating). [EC: 1.1.1.343]
    6-phospho-D-gluconate + NAD(+) = D-ribulose 5-phosphate + CO(2) + NADH.
    • Highly specific for NAD(+).
    • The enzyme catalyzes both the oxidation and decarboxylation of 6-phospho-D-gluconate.
    • In the bacterium Methylobacillus flagellatus the enzyme participates in a formaldehyde oxidation pathway.
    • Cf. EC 1.1.1.44.
    		 6 A0A0B0HW36 A0A0H4PD20 A0A0H4RD59 A0A0K6L0J6 A0A0K6MDJ9 G2RUJ4