The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17562: Mannitol dehydrogenase domain protein

There are 6 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Tagaturonate reductase. [EC: 1.1.1.58]
D-altronate + NAD(+) = D-tagaturonate + NADH.
    1782 A0A014PTU6 A0A014PTU6 A0A017IHS8 A0A017IHS8 A0A023V8U6 A0A023V8U6 A0A023VCB4 A0A023VCB4 A0A023YX54 A0A023YX54
    (1772 more...)
    Fructuronate reductase. [EC: 1.1.1.57]
    D-mannonate + NAD(+) = D-fructuronate + NADH.
    • Also reduces D-tagaturonate.
    1252 A0A023YWS7 A0A023YWS7 A0A023Z098 A0A023Z098 A0A023Z734 A0A023Z734 A0A024KG49 A0A024KG49 A0A024KMM8 A0A024KMM8
    (1242 more...)
    Mannitol 2-dehydrogenase. [EC: 1.1.1.67]
    D-mannitol + NAD(+) = D-fructose + NADH.
      392 A0A024L1Z9 A0A024L1Z9 A0A031IZA5 A0A031IZA5 A0A037Y528 A0A037Y528 A0A068HHD4 A0A068HHD4 A0A069XT13 A0A069XT13
      (382 more...)
      D-arabinitol 4-dehydrogenase. [EC: 1.1.1.11]
      D-arabinitol + NAD(+) = D-xylulose + NADH.
        150 A0A024L1Z9 A0A024L1Z9 A0A060V3K9 A0A060V3K9 A0A068YVV9 A0A068YVV9 A0A085GIW6 A0A085GIW6 A0A085HPS6 A0A085HPS6
        (140 more...)
        Xylulokinase. [EC: 2.7.1.17]
        ATP + D-xylulose = ADP + D-xylulose 5-phosphate.
          6 A0A0N0EZL9 A0A0N0EZL9 D4E309 D4E309 Q48IJ4 Q48IJ4
          Mannitol-1-phosphate 5-dehydrogenase. [EC: 1.1.1.17]
          D-mannitol 1-phosphate + NAD(+) = D-fructose 6-phosphate + NADH.
            4 A0A0T8KVK6 A0A0T8KVK6 E0SMJ7 E0SMJ7
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