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CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17557: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Carnitine 3-dehydrogenase. [EC: 1.1.1.108]
Carnitine + NAD(+) = 3-dehydrocarnitine + NADH.
    		 1170 A0A010T3C4 A0A011V9S0 A0A011VLH4 A0A014MQA8 A0A021XAD0 A0A023C803 A0A024EDK6 A0A024HQX0 A0A024P8I1 A0A024QE23
    (1160 more...)
    3-hydroxybutyryl-CoA dehydrogenase. [EC: 1.1.1.157]
    (S)-3-hydroxybutanoyl-CoA + NADP(+) = 3-acetoacetyl-CoA + NADPH.
      		 37 A0A0C1R7A9 A0A0F4R7H7 A0A0G7HHN3 A0A0J8ACN2 A0A0M3U7J5 A0A0M4R707 A0A0N0XW09 A0A0N1JW85 A0A0P0SID1 A0A0Q7BLS2
      (27 more...)
      3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.35]
      (S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
      • Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate.
      • Some enzymes act, more slowly, with NADP(+).
      • Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
      		 12 A0A017HAX6 A0A017HN07 A0A073IH87 A0A077M1R9 A0A0R2QUS4 A0A160TV81 A0A1D7W3F9 A0A1L3L4X4 A0A1L7SCE6 A4FGG2
      (2 more...)