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CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17554: Enoyl-CoA hydratase/3-hydroxyacyl-CoA dehydrogenas...

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.35]
(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
  • Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate.
  • Some enzymes act, more slowly, with NADP(+).
  • Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
 107 A0A023PCU3 A0A072NTJ8 A0A084IV95 A0A0A8X517 A0A0B5SDY5 A0A0D0GZ52 A0A0D0RN56 A0A0D6T2E6 A0A0E1LRP4 A0A0E8TB70
(97 more...)
Enoyl-CoA hydratase. [EC: 4.2.1.17]
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
  • Acts in the reverse direction.
  • With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
 55 A0A084IV95 A0A0A8X517 A0A0B5SDY5 A0A0D6T2E6 A0A0E1LRP4 A0A0F6J1T7 A0A0G8BVP3 A0A0G8EEX2 A0A0G8EQG6 A0A0K0HYY8
(45 more...)
Dodecenoyl-CoA isomerase. [EC: 5.3.3.8]
(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.
  • Also catalyzes the interconversion of 3-acetylenic fatty acyl thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty acid chain lengths C(6) to C(12).
 2 Q3EVL1 S7SUD7
3-hydroxybutyryl-CoA epimerase. [EC: 5.1.2.3]
(S)-3-hydroxybutanoyl-CoA = (R)-3-hydroxybutanoyl-CoA.
    		 1 S6FZA3
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