The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17543: Mannitol-1-phosphate 5-dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Mannitol-1-phosphate 5-dehydrogenase activity GO:0008926
Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
3 P09424 (/IDA) Q4X1A4 (/IDA) Q8NJJ1 (/IDA)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
2 Q4X1A4 (/IDA) Q8NJJ1 (/IDA)
Mannitol-1-phosphate 5-dehydrogenase activity GO:0008926
Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
1 Q9KKQ6 (/ISS)
Mannitol-1-phosphate 5-dehydrogenase activity GO:0008926
Catalysis of the reaction: D-mannitol 1-phosphate + NAD+ = D-fructose 6-phosphate + NADH + H+.
1 Q5B0F5 (/RCA)

There are 11 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Carbohydrate metabolic process GO:0005975
The chemical reactions and pathways involving carbohydrates, any of a group of organic compounds based of the general formula Cx(H2O)y. Includes the formation of carbohydrate derivatives by the addition of a carbohydrate residue to another molecule.
1 Q9KKQ6 (/ISS)
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 Q8NJJ1 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q8NJJ1 (/IMP)
Mannitol catabolic process GO:0019592
The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 P09424 (/IEP)
Mannitol catabolic process GO:0019592
The chemical reactions and pathways resulting in the breakdown of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 P09424 (/IMP)
Mannitol biosynthetic process GO:0019593
The chemical reactions and pathways resulting in the formation of mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 A2QD49 (/IMP)
Mannitol metabolic process GO:0019594
The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 Q4X1A4 (/IC)
Mannitol metabolic process GO:0019594
The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 Q8NJJ1 (/IMP)
Mannitol metabolic process GO:0019594
The chemical reactions and pathways involving mannitol, the alditol derived from D-mannose by reduction of the aldehyde group.
1 Q5B0F5 (/RCA)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
1 A2QD49 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 A2QD49 (/IMP)

There are 3 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Extracellular region GO:0005576
The space external to the outermost structure of a cell. For cells without external protective or external encapsulating structures this refers to space outside of the plasma membrane. This term covers the host cell environment outside an intracellular parasite.
1 Q5B0F5 (/IDA)
Intracellular GO:0005622
The living contents of a cell; the matter contained within (but not including) the plasma membrane, usually taken to exclude large vacuoles and masses of secretory or ingested material. In eukaryotes it includes the nucleus and cytoplasm.
1 Q4X1A4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P09424 (/IDA)