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CATH Superfamily 1.10.1040.10

N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2

The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
N-(1-d-carboxylethyl)-l-norvaline Dehydrogenase; domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 17290: Putative fatty acid oxidation complex trifunctiona...

There are 3 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
3-hydroxyacyl-CoA dehydrogenase. [EC: 1.1.1.35]
(S)-3-hydroxyacyl-CoA + NAD(+) = 3-oxoacyl-CoA + NADH.
  • Also oxidizes S-3-hydroxyacyl-N-acylthioethanolamine and S-3- hydroxyacylhydrolipoate.
  • Some enzymes act, more slowly, with NADP(+).
  • Broad specificity to acyl chain-length (cf. EC 1.1.1.211).
 5 A0A0F3MTR6 D5AXF5 Q4UL32 Q68WH7 Q9ZCZ1
Dodecenoyl-CoA isomerase. [EC: 5.3.3.8]
(3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA.
  • Also catalyzes the interconversion of 3-acetylenic fatty acyl thioesters and (+)-2,3-dienoyl fatty acyl thioesters, with fatty acid chain lengths C(6) to C(12).
 5 A0A0F3MTR6 D5AXF5 Q4UL32 Q68WH7 Q9ZCZ1
Enoyl-CoA hydratase. [EC: 4.2.1.17]
(3S)-3-hydroxyacyl-CoA = trans-2(or 3)-enoyl-CoA + H(2)O.
  • Acts in the reverse direction.
  • With cis-compounds, yields (3R)-3-hydroxyacyl-CoA (cf. EC 4.2.1.74).
 5 A0A0F3MTR6 D5AXF5 Q4UL32 Q68WH7 Q9ZCZ1
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