The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 124717: Homeobox transcription factor Meis3
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 43 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
26 |
A0A098 (/IPI)
A1Z913 (/IPI)
O00470 (/IPI)
O14770 (/IPI)
O46339 (/IPI)
O70477 (/IPI)
P46639 (/IPI)
P46640 (/IPI)
P48000 (/IPI)
P48002 (/IPI)
(16 more) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
22 |
F4IFQ2 (/ISS)
O65685 (/ISS)
P46609 (/ISS)
P46639 (/ISS)
P46640 (/ISS)
P48000 (/ISS)
P48001 (/ISS)
P48002 (/ISS)
P48731 (/ISS)
Q1PFD1 (/ISS)
(12 more) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
12 |
E7EXR6 (/IDA)
O14770 (/IDA)
O70477 (/IDA)
P48731 (/IDA)
P79937 (/IDA)
P97367 (/IDA)
Q60954 (/IDA)
Q8BG99 (/IDA)
Q90VY7 (/IDA)
Q90ZE3 (/IDA)
(2 more) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
8 | O46339 (/IDA) O70477 (/IDA) P97367 (/IDA) Q60954 (/IDA) Q8BG99 (/IDA) Q90655 (/IDA) Q90ZE3 (/IDA) Q9SJ56 (/IDA) |
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
7 | A1Z913 (/IDA) A1Z916 (/IDA) O14770 (/IDA) P97368 (/IDA) Q60954 (/IDA) Q7JR08 (/IDA) Q7K380 (/IDA) |
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
4 | O14770 (/IDA) P41817 (/IDA) Q15583 (/IDA) Q60954 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
4 | P48731 (/ISS) Q5U4X3 (/ISS) Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
|
4 | P53147 (/IDA) P70284 (/IDA) P97368 (/IDA) Q60954 (/IDA) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
3 | O46339 (/TAS) P55347 (/TAS) Q15583 (/TAS) |
Transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding GO:0003705
Interacting selectively and non-covalently with a sequence of DNA that is in a distal enhancer region for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
|
3 | O46339 (/IDA) O70477 (/IDA) Q60954 (/IDA) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
3 | P97367 (/IGI) Q60954 (/IGI) Q8BG99 (/IGI) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
3 | O70477 (/IPI) Q60954 (/IPI) Q9SJ56 (/IPI) |
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
|
2 | P70284 (/ISO) P97367 (/ISO) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | O46339 (/IMP) P46609 (/IMP) |
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | O14770 (/NAS) Q9GZN2 (/NAS) |
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
|
2 | O14770 (/TAS) Q15583 (/TAS) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
2 | P97367 (/ISO) P97368 (/ISO) |
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q86IH1 (/IDA) |
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
|
1 | Q8BG99 (/IDA) |
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q8BG99 (/IC) |
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | P97367 (/ISO) |
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q15583 (/IDA) |
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q15583 (/IMP) |
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P70284 (/ISO) |
RNA polymerase II repressing transcription factor binding GO:0001103
Interacting selectively and non-covalently with an RNA polymerase II transcription repressing factor, a protein involved in negative regulation of transcription.
|
1 | P41817 (/IPI) |
RNA polymerase II transcription factor activity, sequence-specific transcription regulatory region DNA binding GO:0001133
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA by RNA polymerase II and recruiting another transcription factor to the DNA in order to modulate transcription by RNAP II.
|
1 | P41817 (/IC) |
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
|
1 | O70477 (/IDA) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | O70477 (/IGI) |
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P46609 (/IMP) |
Transcription cofactor activity GO:0003712
Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
1 | P97367 (/IDA) |
Transcription cofactor activity GO:0003712
Interacting selectively and non-covalently with a regulatory transcription factor and also with the basal transcription machinery in order to modulate transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between regulatory transcription factors and the basal transcription machinery.
|
1 | O14770 (/ISS) |
Actin monomer binding GO:0003785
Interacting selectively and non-covalently with monomeric actin, also known as G-actin.
|
1 | Q8BG99 (/IDA) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | P97367 (/IDA) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | O46339 (/IPI) |
Transcription factor binding GO:0008134
Interacting selectively and non-covalently with a transcription factor, any protein required to initiate or regulate transcription.
|
1 | O14770 (/ISS) |
JUN kinase binding GO:0008432
Interacting selectively and non-covalently with JUN kinase, an enzyme that catalyzes the phosphorylation and activation of members of the JUN family.
|
1 | P70284 (/ISO) |
Enhancer binding GO:0035326
Interacting selectively and non-covalently with an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
|
1 | O46339 (/IPI) |
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | Q9SJ56 (/IPI) |
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | Q9FWS9 (/IPI) |
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
|
1 | O65685 (/IPI) |
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
|
1 | O46339 (/IDA) |
Actin filament binding GO:0051015
Interacting selectively and non-covalently with an actin filament, also known as F-actin, a helical filamentous polymer of globular G-actin subunits.
|
1 | Q8BG99 (/IDA) |
Co-SMAD binding GO:0070410
Interacting selectively and non-covalently with a common mediator SMAD signaling protein.
|
1 | Q5BJZ9 (/IPI) |
There are 194 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
5 | A1Z913 (/IDA) A1Z916 (/IDA) P79937 (/IDA) Q7JR08 (/IDA) Q7K380 (/IDA) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | O14770 (/IDA) O46339 (/IDA) O70477 (/IDA) P79937 (/IDA) Q60954 (/IDA) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
4 | A1Z913 (/IEP) A1Z916 (/IEP) Q7JR08 (/IEP) Q7K380 (/IEP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
4 | A1Z913 (/IMP) A1Z916 (/IMP) Q7JR08 (/IMP) Q7K380 (/IMP) |
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
|
4 | A1Z913 (/IPI) A1Z916 (/IPI) Q7JR08 (/IPI) Q7K380 (/IPI) |
Embryonic viscerocranium morphogenesis GO:0048703
The process in which the anatomical structures of the viscerocranium are generated and organized during the embryonic phase. The viscerocranium is the part of the skull comprising the facial bones.
|
4 | A0A0H2UKR5 (/IMP) Q6NZT1 (/IMP) Q90XH2 (/IMP) Q9DDE0 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
3 | O14770 (/TAS) Q15583 (/TAS) Q9GZN2 (/TAS) |
Angiogenesis GO:0001525
Blood vessel formation when new vessels emerge from the proliferation of pre-existing blood vessels.
|
3 | O70477 (/IMP) Q60954 (/IMP) Q90XH2 (/IMP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
3 | A0A0R4IZP4 (/IGI) H0WF09 (/IGI) Q7SZP3 (/IGI) |
Xylem development GO:0010089
The formation of the principal water-conducting tissue of a vascular plant.
|
3 | P46639 (/IMP) Q9FPQ8 (/IMP) Q9LZM8 (/IMP) |
Regulation of transforming growth factor beta receptor signaling pathway GO:0017015
Any process that modulates the frequency, rate or extent of activity of any TGF-beta receptor signaling pathway.
|
3 | F8W267 (/IMP) Q803F0 (/IMP) R4GEZ0 (/IMP) |
Forebrain anterior/posterior pattern specification GO:0021797
The creation of specific areas of progenitor domains along the anterior-posterior axis of the developing forebrain.
|
3 | F8W267 (/IGI) Q803F0 (/IGI) R4GEZ0 (/IGI) |
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
|
3 | E7EXR6 (/IMP) Q5U4X3 (/IMP) Q90VY7 (/IMP) |
Positive regulation of histone acetylation GO:0035066
Any process that activates or increases the frequency, rate or extent of the addition of an acetyl group to a histone protein.
|
3 | E7EXR6 (/IGI) Q90VY7 (/IGI) Q90ZE3 (/IGI) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
3 | A1Z916 (/IMP) Q5U4X3 (/IMP) Q7JR08 (/IMP) |
Regulation of retinoic acid receptor signaling pathway GO:0048385
Any process that modulates the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
|
3 | F8W267 (/IMP) Q803F0 (/IMP) R4GEZ0 (/IMP) |
Brain morphogenesis GO:0048854
The process in which the anatomical structures of the brain are generated and organized. The brain is one of the two components of the central nervous system and is the center of thought and emotion. It is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
3 | F8W267 (/IMP) Q803F0 (/IMP) R4GEZ0 (/IMP) |
Sensory epithelium regeneration GO:0070654
The regrowth of a sensory epithelium following its loss or destruction.
|
3 | F8W267 (/IGI) Q803F0 (/IGI) R4GEZ0 (/IGI) |
Sensory epithelium regeneration GO:0070654
The regrowth of a sensory epithelium following its loss or destruction.
|
3 | F8W267 (/IMP) Q803F0 (/IMP) R4GEZ0 (/IMP) |
Regulation of stem cell proliferation GO:0072091
Any process that modulates the frequency, rate or extent of stem cell proliferation. A stem cell is a cell that retains the ability to divide and proliferate throughout life to provide progenitor cells that can differentiate into specialized cells.
|
3 | F8W267 (/IMP) Q803F0 (/IMP) R4GEZ0 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q15583 (/IMP) Q9GZN2 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P70284 (/ISO) Q8C0Y1 (/ISO) |
Heart looping GO:0001947
The tube morphogenesis process in which the primitive heart tube loops asymmetrically. This looping brings the primitive heart chambers into alignment preceding their future integration. Heart looping begins with dextral-looping and ends when the main regional divisions of the mature heart and primordium of the great arterial trunks become established preceeding septation.
|
2 | Q90XH2 (/IMP) Q9DDE0 (/IMP) |
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
|
2 | O14770 (/TAS) P55347 (/TAS) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
|
2 | P48731 (/IMP) P70284 (/IMP) |
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
|
2 | P48000 (/IEP) P48001 (/IEP) |
Response to mechanical stimulus GO:0009612
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a mechanical stimulus.
|
2 | A0A0G2JT27 (/IEP) D4A2T5 (/IEP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Leaf morphogenesis GO:0009965
The process in which the anatomical structures of the leaf are generated and organized.
|
2 | Q94KL5 (/IGI) Q9SW80 (/IGI) |
Xylem and phloem pattern formation GO:0010051
The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
|
2 | P46639 (/IMP) Q9LZM8 (/IMP) |
Maintenance of floral meristem identity GO:0010076
The process in which an organism retains a population of floral meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
|
2 | Q9LZM8 (/IGI) Q9SJJ3 (/IGI) |
Maintenance of inflorescence meristem identity GO:0010077
The process in which an organism retains a population of inflorescence meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
|
2 | Q9LZM8 (/IGI) Q9SJJ3 (/IGI) |
Secondary shoot formation GO:0010223
The process that gives rise to secondary (or auxiliary or axillary) shoots in plants. This process pertains to the initial formation of a structure from unspecified parts. These secondary shoots originate from secondary meristems initiated in the axils of leaf primordia. Axillary meristems function like the shoot apical meristem of the primary shoot initating the development of lateral organs.
|
2 | Q9LZM8 (/IGI) Q9SJJ3 (/IGI) |
Vegetative to reproductive phase transition of meristem GO:0010228
The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
|
2 | Q9LZM8 (/IGI) Q9SJJ3 (/IGI) |
Regulation of gastrulation GO:0010470
Any process that modulates the rate or extent of gastrulation. Gastrulation is the complex and coordinated series of cellular movements that occurs at the end of cleavage during embryonic development of most animals.
|
2 | P70284 (/IGI) Q8C0Y1 (/IGI) |
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
2 | Q5BJZ9 (/IMP) Q86IH1 (/IMP) |
Neural crest cell differentiation GO:0014033
The process in which a relatively unspecialized cell acquires specialized features of a neural crest cell.
|
2 | E7EXR6 (/IMP) Q90VY7 (/IMP) |
Hemopoiesis GO:0030097
The process whose specific outcome is the progression of the myeloid and lymphoid derived organ/tissue systems of the blood and other parts of the body over time, from formation to the mature structure. The site of hemopoiesis is variable during development, but occurs primarily in bone marrow or kidney in many adult vertebrates.
|
2 | O70477 (/IMP) Q60954 (/IMP) |
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
|
2 | A0A0G2JT27 (/IEP) D4A2T5 (/IEP) |
Regulation of histone methylation GO:0031060
Any process that modulates the frequency, rate or extent of the covalent addition of methyl groups to histones.
|
2 | E7EXR6 (/IGI) Q90VY7 (/IGI) |
Negative regulation of histone methylation GO:0031061
Any process that stops, prevents, or reduces the frequency, rate or extent of the covalent addition of methyl groups to histones.
|
2 | E7EXR6 (/IGI) Q90VY7 (/IGI) |
Nodal signaling pathway GO:0038092
A series of molecular signals initiated by the binding of a nodal protein to an activin receptor on the surface of a target cell, and ending with regulation of a downstream cellular process, e.g. transcription.
|
2 | P70284 (/IGI) Q8C0Y1 (/IGI) |
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
2 | P97367 (/IDA) Q60954 (/IDA) |
Negative regulation of myeloid cell differentiation GO:0045638
Any process that stops, prevents, or reduces the frequency, rate or extent of myeloid cell differentiation.
|
2 | O00470 (/ISS) O14770 (/ISS) |
Positive regulation of neuron differentiation GO:0045666
Any process that activates or increases the frequency, rate or extent of neuron differentiation.
|
2 | P70284 (/IDA) Q8C0Y1 (/IDA) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q90655 (/IDA) Q9FPQ8 (/IDA) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P79937 (/IGI) Q90ZE3 (/IGI) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | P79937 (/IGI) Q90ZE3 (/IGI) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | O46339 (/IMP) Q5U4X3 (/IMP) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
2 | Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Retinoic acid receptor signaling pathway GO:0048384
The series of molecular signals generated as a consequence of a retinoic acid receptor binding to one of its physiological ligands.
|
2 | B8A551 (/IMP) E7FBG0 (/IMP) |
Pharyngeal system development GO:0060037
The process whose specific outcome is the progression of the pharyngeal system over time, from its formation to the mature structure. The pharyngeal system is a transient embryonic complex that is specific to vertebrates. It comprises the pharyngeal arches, bulges of tissues of mesoderm and neural crest derivation through which pass nerves and pharyngeal arch arteries. The arches are separated internally by pharyngeal pouches, evaginations of foregut endoderm, and externally by pharyngeal clefts, invaginations of surface ectoderm. The development of the system ends when the stucture it contributes to are forming: the thymus, thyroid, parathyroids, maxilla, mandible, aortic arch, cardiac outflow tract, external and middle ear.
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2 | B8A551 (/IMP) E7FBG0 (/IMP) |
Retina development in camera-type eye GO:0060041
The process whose specific outcome is the progression of the retina over time, from its formation to the mature structure. The retina is the innermost layer or coating at the back of the eyeball, which is sensitive to light and in which the optic nerve terminates.
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2 | P70284 (/IDA) Q8C0Y1 (/IDA) |
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
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2 | Q60954 (/IMP) Q90XH2 (/IMP) |
Response to growth factor GO:0070848
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
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2 | A0A0G2JT27 (/IEP) D4A2T5 (/IEP) |
Plant organ formation GO:1905393
The process that gives rise to the plant organ. This process pertains to the initial formation of a structure from unspecified parts.
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2 | Q9LZM8 (/IGI) Q9SJJ3 (/IGI) |
Protein import into nucleus, translocation GO:0000060
A protein transport process that contributes to protein import into the nucleus, and that results in the vectorial transfer of a cargo-carrier protein complex through the nuclear pore complex from the cytoplasmic side to the nucleoplasmic side of the nuclear envelope.
|
1 | O46339 (/IMP) |
G1/S transition of mitotic cell cycle GO:0000082
The mitotic cell cycle transition by which a cell in G1 commits to S phase. The process begins with the build up of G1 cyclin-dependent kinase (G1 CDK), resulting in the activation of transcription of G1 cyclins. The process ends with the positive feedback of the G1 cyclins on the G1 CDK which commits the cell to S phase, in which DNA replication is initiated.
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1 | Q90XH2 (/IMP) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
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1 | Q15583 (/IDA) |
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P70284 (/IGI) |
Mitotic cytokinesis GO:0000281
A cell cycle process that results in the division of the cytoplasm of a cell after mitosis, resulting in the separation of the original cell into two daughter cells.
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1 | Q86IH1 (/IMP) |
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | P97367 (/IGI) |
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
|
1 | O46339 (/IMP) |
Cell fate specification GO:0001708
The process involved in the specification of cell identity. Once specification has taken place, a cell will be committed to differentiate down a specific pathway if left in its normal environment.
|
1 | P46639 (/IMP) |
Compound eye photoreceptor fate commitment GO:0001752
The process in which the developmental fate of a cell becomes restricted such that it will develop into a compound eye photoreceptor cell. A photoreceptor cell is a cell that responds to incident electromagnetic radiation. Different classes of photoreceptor have different spectral sensitivities and express different photosensitive pigments.
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1 | O46339 (/IMP) |
Neural tube closure GO:0001843
The last step in the formation of the neural tube, where the paired neural folds are brought together and fuse at the dorsal midline.
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1 | P70284 (/IMP) |
Endothelial cell development GO:0001885
The progression of an endothelial cell over time, from its formation to the mature structure.
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1 | Q90XH2 (/IMP) |
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
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1 | Q90XH2 (/IGI) |
Lens morphogenesis in camera-type eye GO:0002089
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
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1 | Q60954 (/IMP) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
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1 | Q60954 (/IDA) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
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1 | P46609 (/IMP) |
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
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1 | Q9GZN2 (/NAS) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q60954 (/IC) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O70477 (/IDA) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q8BG99 (/IGI) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O46339 (/IMP) |
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | O70477 (/TAS) |
Multicellular organism development GO:0007275
The biological process whose specific outcome is the progression of a multicellular organism over time from an initial condition (e.g. a zygote or a young adult) to a later condition (e.g. a multicellular animal or an aged adult).
|
1 | Q15583 (/TAS) |
Determination of left/right symmetry GO:0007368
The establishment of an organism's body plan or part of an organism with respect to the left and right halves. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
|
1 | P70284 (/IMP) |
Specification of segmental identity, head GO:0007380
The specification of the characteristic structures of the head segments following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
1 | O46339 (/IMP) |
Specification of segmental identity, antennal segment GO:0007383
The specification of the characteristic structures of the antennal segment following establishment of segment boundaries. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
1 | O46339 (/IMP) |
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
|
1 | Q9SJJ3 (/IGI) |
Pattern specification process GO:0007389
Any developmental process that results in the creation of defined areas or spaces within an organism to which cells respond and eventually are instructed to differentiate.
|
1 | Q9LZM8 (/IMP) |
Central nervous system development GO:0007417
The process whose specific outcome is the progression of the central nervous system over time, from its formation to the mature structure. The central nervous system is the core nervous system that serves an integrating and coordinating function. In vertebrates it consists of the brain and spinal cord. In those invertebrates with a central nervous system it typically consists of a brain, cerebral ganglia and a nerve cord.
|
1 | Q5U4X3 (/IMP) |
Brain development GO:0007420
The process whose specific outcome is the progression of the brain over time, from its formation to the mature structure. Brain development begins with patterning events in the neural tube and ends with the mature structure that is the center of thought and emotion. The brain is responsible for the coordination and control of bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.).
|
1 | O46339 (/IMP) |
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
|
1 | O46339 (/IMP) |
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
|
1 | O46339 (/NAS) |
Peripheral nervous system development GO:0007422
The process whose specific outcome is the progression of the peripheral nervous system over time, from its formation to the mature structure. The peripheral nervous system is one of the two major divisions of the nervous system. Nerves in the PNS connect the central nervous system (CNS) with sensory organs, other organs, muscles, blood vessels and glands.
|
1 | O46339 (/TAS) |
Salivary gland boundary specification GO:0007432
Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
|
1 | O46339 (/NAS) |
Salivary gland boundary specification GO:0007432
Determination of where the salivary gland forms, the total number of salivary gland cells and how many cells are allocated to each of the specialised cell types within the salivary gland.
|
1 | O46339 (/TAS) |
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
1 | O46339 (/IMP) |
Leg disc proximal/distal pattern formation GO:0007479
The establishment, maintenance and elaboration of the proximal/distal axis of the leg imaginal disc, a precursor to the adult leg.
|
1 | O46339 (/TAS) |
Imaginal disc-derived leg morphogenesis GO:0007480
The process in which the anatomical structures of a leg derived from an imaginal disc are generated and organized. A leg is a limb on which an animal walks and stands. An example of this is found in Drosophila melanogaster.
|
1 | O46339 (/IMP) |
Mesodermal cell fate specification GO:0007501
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | Q9N5D6 (/IGI) |
Mesodermal cell fate specification GO:0007501
The cell fate determination process in which a cell becomes capable of differentiating autonomously into a mesoderm cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | Q9N5D6 (/IMP) |
Heart development GO:0007507
The process whose specific outcome is the progression of the heart over time, from its formation to the mature structure. The heart is a hollow, muscular organ, which, by contracting rhythmically, keeps up the circulation of the blood.
|
1 | Q9DDE0 (/IMP) |
Somatic muscle development GO:0007525
The process whose specific outcome is the progression of the somatic muscle over time, from its formation to the mature structure. Somatic muscles are striated muscle structures that connect to the exoskeleton or cuticle.
|
1 | O46339 (/IMP) |
Locomotory behavior GO:0007626
The specific movement from place to place of an organism in response to external or internal stimuli. Locomotion of a whole organism in a manner dependent upon some combination of that organism's internal state and external conditions.
|
1 | Q60954 (/IMP) |
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
|
1 | P97367 (/IMP) |
Response to symbiotic fungus GO:0009610
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a symbiotic fungus, a fungus living in close physical association with another organism.
|
1 | Q9SJ56 (/IEP) |
Photomorphogenesis GO:0009640
The control of plant growth, development, and differentiation by the duration and nature of light, independent of photosynthesis.
|
1 | P48731 (/IDA) |
Cytokinin biosynthetic process GO:0009691
The chemical reactions and pathways resulting in the formation of cytokinins, a class of adenine-derived compounds that can function in plants as growth regulators.
|
1 | Q38874 (/TAS) |
Detection of cytokinin stimulus GO:0009722
The series of events in which a cytokinin stimulus is received by a cell and converted into a molecular signal.
|
1 | P48000 (/IEP) |
Detection of ethylene stimulus GO:0009727
The series of events in which an ethylene (ethene) stimulus is received by a cell and converted into a molecular signal.
|
1 | P48002 (/IEP) |
Cytokinin-activated signaling pathway GO:0009736
A series of molecular signals generated by the binding of a cytokinin to a receptor, and ending with regulation of a downstream cellular process, e.g. transcription.
|
1 | P46640 (/IMP) |
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
|
1 | Q9SJ56 (/IEP) |
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
|
1 | Q90XH2 (/IMP) |
Regulation of meristem structural organization GO:0009934
Any process that modulates the frequency, rate or extent of meristem organization.
|
1 | Q38874 (/IMP) |
Anterior/posterior pattern specification GO:0009952
The regionalization process in which specific areas of cell differentiation are determined along the anterior-posterior axis. The anterior-posterior axis is defined by a line that runs from the head or mouth of an organism to the tail or opposite end of the organism.
|
1 | Q5U4X3 (/IMP) |
Dorsal/ventral pattern formation GO:0009953
The regionalization process in which the areas along the dorsal/ventral axis are established that will lead to differences in cell differentiation. The dorsal/ventral axis is defined by a line that runs orthogonal to both the anterior/posterior and left/right axes. The dorsal end is defined by the upper or back side of an organism. The ventral end is defined by the lower or front side of an organism.
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1 | P70284 (/IMP) |
Proximal/distal pattern formation GO:0009954
The regionalization process in which specific areas of cell differentiation are determined along a proximal/distal axis. The proximal/distal axis is defined by a line that runs from main body (proximal end) of an organism outward (distal end).
|
1 | O46339 (/TAS) |
Meristem maintenance GO:0010073
Any process involved in maintaining the identity, size and shape of a meristem.
|
1 | Q84JS6 (/IGI) |
Specification of animal organ identity GO:0010092
The regionalization process in which the identity of an animal organ primordium is specified. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
1 | O46339 (/TAS) |
Specification of carpel identity GO:0010094
The process in which a floral organ primordium acquires the carpel identity. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
|
1 | P46640 (/IMP) |
Fruit development GO:0010154
The process whose specific outcome is the progression of the fruit over time, from its formation to the mature structure. The fruit is a reproductive body of a seed plant.
|
1 | Q9LZM8 (/IMP) |
Mucilage biosynthetic process GO:0010192
The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.
|
1 | Q9FPQ8 (/IMP) |
Polar nucleus fusion GO:0010197
The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
|
1 | Q9SJ56 (/IMP) |
Response to continuous far red light stimulus by the high-irradiance response system GO:0010201
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of the detection of a continuous far red light stimulus by the high-irradiance response system. Far red light is electromagnetic radiation of wavelength 700-800nm. The activity of the high-irradiance response system is characterized by stronger effects of continuous than pulsed light at equal total fluence.
|
1 | Q9SJ56 (/IMP) |
Floral organ abscission GO:0010227
The controlled shedding of floral organs.
|
1 | P48731 (/IMP) |
Vegetative to reproductive phase transition of meristem GO:0010228
The process involved in transforming a meristem that produces vegetative structures, such as leaves, into a meristem that produces reproductive structures, such as a flower or an inflorescence.
|
1 | P48731 (/IMP) |
Inflorescence development GO:0010229
The process whose specific outcome is the progression of an inflorescence over time, from its formation to the mature structure.
|
1 | Q9SJJ3 (/IGI) |
Regulation of gibberellin biosynthetic process GO:0010371
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of gibberellins.
|
1 | P48731 (/IMP) |
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
|
1 | Q54VB4 (/IMP) |
Neural crest cell fate specification GO:0014036
The process in which a cell becomes capable of differentiating autonomously into a neural crest cell in an environment that is neutral with respect to the developmental pathway; upon specification, the cell fate can be reversed.
|
1 | P79937 (/IGI) |
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
|
1 | Q38874 (/TAS) |
T cell differentiation GO:0030217
The process in which a precursor cell type acquires characteristics of a more mature T-cell. A T cell is a type of lymphocyte whose definin characteristic is the expression of a T cell receptor complex.
|
1 | O70477 (/IMP) |
Erythrocyte differentiation GO:0030218
The process in which a myeloid precursor cell acquires specializes features of an erythrocyte.
|
1 | O70477 (/IMP) |
Neutrophil differentiation GO:0030223
The process in which a myeloid precursor cell acquires the specialized features of a neutrophil.
|
1 | Q90XH2 (/IMP) |
Macrophage differentiation GO:0030225
The process in which a relatively unspecialized monocyte acquires the specialized features of a macrophage.
|
1 | Q90XH2 (/IMP) |
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
|
1 | Q5AH24 (/IMP) |
Hindbrain development GO:0030902
The process whose specific outcome is the progression of the hindbrain over time, from its formation to the mature structure. The hindbrain is the posterior of the three primary divisions of the developing chordate brain, or the corresponding part of the adult brain (in vertebrates, includes the cerebellum, pons, and medulla oblongata and controls the autonomic functions and equilibrium).
|
1 | Q90ZE3 (/IGI) |
Pancreas development GO:0031016
The process whose specific outcome is the progression of the pancreas over time, from its formation to the mature structure. The pancreas is an endoderm derived structure that produces precursors of digestive enzymes and blood glucose regulating enzymes.
|
1 | Q90ZE3 (/IMP) |
Exocrine pancreas development GO:0031017
The process whose specific outcome is the progression of the exocrine pancreas over time, from its formation to the mature structure. The exocrine pancreas produces and store zymogens of digestive enzymes, such as chymotrypsinogen and trypsinogen in the acinar cells.
|
1 | Q90ZE3 (/IMP) |
Slug development involved in sorocarp development GO:0031153
The process whose specific outcome is the progression of the slug over time, from its formation to the mature structure. Slug development begins when the aggregate rises upwards to form a finger-shaped structure and ends when culmination begins. Slug development begins after aggregation and ends before culmination in sorocarp development.
|
1 | Q86IH1 (/IMP) |
Protein localization to nucleus GO:0034504
A process in which a protein is transported to, or maintained in, a location within the nucleus.
|
1 | O46339 (/IPI) |
Segmentation GO:0035282
The regionalization process that divides an organism or part of an organism into a series of semi-repetitive parts, or segments, often arranged along a longitudinal axis.
|
1 | O46339 (/IMP) |
Angioblast cell migration GO:0035476
The orderly movement of angioblasts, cells involved in blood vessel morphogenesis.
|
1 | Q90XH2 (/IMP) |
Megakaryocyte development GO:0035855
The process whose specific outcome is the progression of a megakaryocyte cell over time, from its formation to the mature structure. Megakaryocyte development does not include the steps involved in committing a cell to a megakaryocyte fate. A megakaryocyte is a giant cell 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow.
|
1 | Q60954 (/IMP) |
Dorsal aorta development GO:0035907
The progression of the dorsal aorta over time, from its initial formation to the mature structure. The dorsal aorta is a blood vessel in a single-pass circulatory system that carries oxygenated blood from the gills to the rest of the body. In a single-pass circulatory system blood passes once through the heart to supply the body once.
|
1 | Q90XH2 (/IMP) |
Negative regulation of oligopeptide transport by negative regulation of transcription from RNA polymerase II promoter GO:0035952
Any process that stops, prevents or reduces the frequency, rate or extent of oligopeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P41817 (/IMP) |
Negative regulation of dipeptide transport by negative regulation of transcription from RNA polymerase II promoter GO:0035955
Any process that stops, prevents or reduces the frequency, rate or extent of dipeptide transport by stopping, preventing or reducing the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P41817 (/IMP) |
Response to drug GO:0042493
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
|
1 | Q5BJZ9 (/IEP) |
Regulation of cell fate specification GO:0042659
Any process that mediates the adoption of a specific fate by a cell.
|
1 | O46339 (/IMP) |
Muscle cell differentiation GO:0042692
The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
|
1 | Q9N5D6 (/IGI) |
Muscle cell differentiation GO:0042692
The process in which a relatively unspecialized cell acquires specialized features of a muscle cell.
|
1 | Q9N5D6 (/IMP) |
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
|
1 | O70477 (/IMP) |
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
|
1 | O46339 (/IDA) |
Positive regulation of MAPK cascade GO:0043410
Any process that activates or increases the frequency, rate or extent of signal transduction mediated by the MAPK cascade.
|
1 | Q5U4X3 (/IMP) |
Regulation of cAMP-mediated signaling GO:0043949
Any process which modulates the frequency, rate or extent of cAMP-mediated signaling, a series of molecular signals in which a cell uses cyclic AMP to convert an extracellular signal into a response.
|
1 | Q54VB4 (/IMP) |
Cell fate commitment GO:0045165
The commitment of cells to specific cell fates and their capacity to differentiate into particular kinds of cells. Positional information is established through protein signals that emanate from a localized source within a cell (the initial one-cell zygote) or within a developmental field.
|
1 | P46639 (/IMP) |
Regulation of neuron differentiation GO:0045664
Any process that modulates the frequency, rate or extent of neuron differentiation.
|
1 | O46339 (/IMP) |
Negative regulation of neuron differentiation GO:0045665
Any process that stops, prevents, or reduces the frequency, rate or extent of neuron differentiation.
|
1 | Q60954 (/IGI) |
Positive regulation of translation GO:0045727
Any process that activates or increases the frequency, rate or extent of the chemical reactions and pathways resulting in the formation of proteins by the translation of mRNA.
|
1 | Q9N5D6 (/IMP) |
Positive regulation of angiogenesis GO:0045766
Any process that activates or increases angiogenesis.
|
1 | Q90XH2 (/IDA) |
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | Q9LZM8 (/IMP) |
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | O70477 (/TAS) |
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | P97367 (/ISO) |
Positive regulation of fibroblast proliferation GO:0048146
Any process that activates or increases the frequency, rate or extent of multiplication or reproduction of fibroblast cells.
|
1 | P70284 (/IMP) |
Shoot system development GO:0048367
The process whose specific outcome is the progression of the shoot system over time, from its formation to the mature structure.
|
1 | Q9LZM8 (/IGI) |
Negative regulation of retinoic acid receptor signaling pathway GO:0048387
Any process that stops, prevents, or reduces the frequency, rate or extent of retinoic acid receptor signaling pathway activity.
|
1 | P70284 (/IMP) |
Carpel development GO:0048440
The process whose specific outcome is the progression of the carpel over time, from its formation to the mature structure. A carpel is an organ (generally believed to be a modified foliar unit) at the centre of a flower, bearing one or more ovules and having its margins fused together or with other carpels to enclose the ovule in an ovary, and consisting also of a stigma and usually a style.
|
1 | Q38874 (/IMP) |
Floral whorl morphogenesis GO:0048457
The process in which the anatomical structures of the floral whorl are generated and organized.
|
1 | Q9LZM8 (/IMP) |
Enteric nervous system development GO:0048484
The process whose specific outcome is the progression of the enteric nervous system over time, from its formation to the mature structure. The enteric nervous system is composed of two ganglionated neural plexuses in the gut wall which form one of the three major divisions of the autonomic nervous system. The enteric nervous system innervates the gastrointestinal tract, the pancreas, and the gall bladder. It contains sensory neurons, interneurons, and motor neurons. Thus the circuitry can autonomously sense the tension and the chemical environment in the gut and regulate blood vessel tone, motility, secretions, and fluid transport. The system is itself governed by the central nervous system and receives both parasympathetic and sympathetic innervation.
|
1 | Q90ZE3 (/IMP) |
Regulation of timing of transition from vegetative to reproductive phase GO:0048510
The process controlling the point in time during development when a vegetative meristem will change its identity to become an inflorescence or floral meristem, and/or the rate at which the change occurs.
|
1 | Q9FWS9 (/IMP) |
Blood vessel morphogenesis GO:0048514
The process in which the anatomical structures of blood vessels are generated and organized. The blood vessel is the vasculature carrying blood.
|
1 | Q60954 (/IMP) |
Haltere morphogenesis GO:0048735
The process in which the anatomical structures of a haltere are generated and organized.
|
1 | O46339 (/IMP) |
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
1 | O46339 (/IGI) |
Compound eye development GO:0048749
The process whose specific outcome is the progression of the compound eye over time, from its formation to the mature structure. The compound eye is an organ of sight that contains multiple repeating units, often arranged hexagonally. Each unit has its own lens and photoreceptor cell(s) and can generate either a single pixelated image or multiple images, per eye.
|
1 | O46339 (/IMP) |
Artery morphogenesis GO:0048844
The process in which the anatomical structures of arterial blood vessels are generated and organized. Arteries are blood vessels that transport blood from the heart to the body and its organs.
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1 | Q90XH2 (/IMP) |
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
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1 | Q90XH2 (/IPI) |
Positive regulation of protein kinase B signaling GO:0051897
Any process that activates or increases the frequency, rate or extent of protein kinase B signaling, a series of reactions mediated by the intracellular serine/threonine kinase protein kinase B.
|
1 | P97368 (/IMP) |
Embryonic retina morphogenesis in camera-type eye GO:0060059
The process in which the anatomical structure of the retina is generated and organized in a camera-type eye during the embryonic life stage.
|
1 | Q90XH2 (/IMP) |
Primitive hemopoiesis GO:0060215
A first transient wave of blood cell production that, in vertebrates, gives rise to erythrocytes (red blood cells) and myeloid cells.
|
1 | Q90XH2 (/IGI) |
Definitive hemopoiesis GO:0060216
A second wave of blood cell production that, in vertebrates, generates long-term hemopoietic stem cells that continously provide erythroid, myeloid and lymphoid lineages throughout adulthood.
|
1 | Q90XH2 (/IGI) |
Primitive erythrocyte differentiation GO:0060319
Erythrocyte differentiation which occurs as part of the process of primitive hemopoiesis.
|
1 | Q90XH2 (/IMP) |
Head morphogenesis GO:0060323
The process in which the anatomical structures of the head are generated and organized. The head is the anterior-most division of the body.
|
1 | O46339 (/IMP) |
Venous blood vessel development GO:0060841
The progression of the venous blood vessel over time from its initial formation to the mature structure. Venous blood vessels carry blood back to the heart after the capillary bed.
|
1 | Q90XH2 (/IMP) |
Cellular response to cytokine stimulus GO:0071345
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cytokine stimulus.
|
1 | P48000 (/IDA) |
Cellular response to growth factor stimulus GO:0071363
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a growth factor stimulus.
|
1 | Q5BJZ9 (/IEP) |
Cellular response to ethylene stimulus GO:0071369
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethylene (ethene) stimulus.
|
1 | P48002 (/IDA) |
Malpighian tubule development GO:0072002
The process whose specific outcome is the progression of the Malpighian tubule over time, from its formation to the mature structure. A Malpighian tubule is a fine, thin-walled excretory tubule in insects which leads into the posterior part of the gut.
|
1 | O46339 (/IMP) |
Blood vessel lumenization GO:0072554
The process in which a developing blood vessel forms an endothelial lumen through which blood will flow.
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1 | Q90XH2 (/IMP) |
Internode patterning GO:0080006
Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.
|
1 | Q9SJJ3 (/IGI) |
Internode patterning GO:0080006
Determines the spacing between two shoot nodes. A shoot node is the region of the shoot where the spikelet, flower, floret, branch, bud and/or leaves are attached.
|
1 | Q9LZM8 (/IMP) |
Positive regulation of decapentaplegic signaling pathway GO:0090098
Any process that increases the frequency, rate, or extent of the decapentaplegic signaling pathway. The decapentaplegic signaling pathway is the series of molecular signals generated as a consequence of the signal decapentaplegic binding to one of its physiological receptors.
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1 | O46339 (/IMP) |
Shoot organ boundary specification GO:0090470
The process in which the basal boundary between the stem and both vegetative and reproductive organs are established and maintained.
|
1 | P48731 (/IMP) |
Neural crest cell migration involved in autonomic nervous system development GO:1901166
Any neural crest cell migration that is involved in autonomic nervous system development.
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1 | Q90ZE3 (/IMP) |
Negative regulation of sorocarp spore cell differentiation GO:1901262
Any process that stops, prevents or reduces the frequency, rate or extent of sorocarp spore cell differentiation.
|
1 | Q86IH1 (/IMP) |
Regulation of secondary cell wall biogenesis GO:2000652
Any process that modulates the frequency, rate or extent of secondary cell wall biogenesis.
|
1 | Q9FPQ8 (/IMP) |
Negative regulation of apoptotic signaling pathway GO:2001234
Any process that stops, prevents or reduces the frequency, rate or extent of apoptotic signaling pathway.
|
1 | P97368 (/IMP) |
There are 22 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
32 |
A1Z913 (/IDA)
A1Z916 (/IDA)
E7EXR6 (/IDA)
O46339 (/IDA)
O70477 (/IDA)
P46640 (/IDA)
P48000 (/IDA)
P48001 (/IDA)
P48002 (/IDA)
P48731 (/IDA)
(22 more) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
8 | E7EXR6 (/IDA) O46339 (/IDA) O70477 (/IDA) P79937 (/IDA) Q8BG99 (/IDA) Q90VY7 (/IDA) Q90ZE3 (/IDA) Q9SJ56 (/IDA) |
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
7 | O46339 (/IDA) P48000 (/IDA) P48001 (/IDA) Q38897 (/IDA) Q90XH2 (/IDA) Q96I87 (/IDA) Q9LZM8 (/IDA) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
6 | F8VUY0 (/IDA) F8VVS9 (/IDA) H0YKN5 (/IDA) Q15583 (/IDA) Q96KN3 (/IDA) Q9GZN2 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
4 | P46639 (/ISS) Q5U4X3 (/ISS) Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
4 | O70477 (/TAS) Q15583 (/TAS) Q60954 (/TAS) Q9GZN2 (/TAS) |
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
3 | P70284 (/ISO) Q8BG99 (/ISO) Q8C0Y1 (/ISO) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
3 | O46339 (/IDA) O70477 (/IDA) Q60954 (/IDA) |
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
|
3 | Q5U4X3 (/ISS) Q6DIF3 (/ISS) Q7ZY13 (/ISS) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
2 | P41817 (/IC) Q90655 (/IC) |
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
|
1 | P53147 (/IDA) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | P46609 (/IMP) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q8BG99 (/ISO) |
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q9GZN2 (/TAS) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | P79937 (/IGI) |
Transcription factor complex GO:0005667
A protein complex that is capable of associating with DNA by direct binding, or via other DNA-binding proteins or complexes, and regulating transcription.
|
1 | O46339 (/IPI) |
Plasmodesma GO:0009506
A fine cytoplasmic channel, found in all higher plants, that connects the cytoplasm of one cell to that of an adjacent cell.
|
1 | Q38897 (/IDA) |
Actin cytoskeleton GO:0015629
The part of the cytoskeleton (the internal framework of a cell) composed of actin and associated proteins. Includes actin cytoskeleton-associated complexes.
|
1 | Q8BG99 (/IDA) |
Microtubule cytoskeleton GO:0015630
The part of the cytoskeleton (the internal framework of a cell) composed of microtubules and associated proteins.
|
1 | Q8BG99 (/IDA) |
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | O46339 (/IDA) |
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
|
1 | Q96KN3 (/IDA) |
Intercellular bridge GO:0045171
A direct connection between the cytoplasm of two cells that is formed following the completion of cleavage furrow ingression during cell division. They are usually present only briefly prior to completion of cytokinesis. However, in some cases, such as the bridges between germ cells during their development, they become stabilised.
|
1 | Q8BG99 (/ISO) |