The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 124677: Histone H2A deubiquitinase MYSM1
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 18 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | Q54Z40 (/ISS) |
|
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | Q5VVJ2 (/IDA) |
|
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
|
1 | Q69Z66 (/ISO) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q5VVJ2 (/IDA) |
|
Thiol-dependent ubiquitin-specific protease activity GO:0004843
Catalysis of the thiol-dependent hydrolysis of a peptide bond formed by the C-terminal glycine of ubiquitin and another protein.
|
1 | Q69Z66 (/ISO) |
|
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
1 | Q5VVJ2 (/IMP) |
|
Metallopeptidase activity GO:0008237
Catalysis of the hydrolysis of peptide bonds by a mechanism in which water acts as a nucleophile, one or two metal ions hold the water molecule in place, and charged amino acid side chains are ligands for the metal ions.
|
1 | Q69Z66 (/ISO) |
|
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q5VVJ2 (/IDA) |
|
Protein complex binding GO:0032403
Interacting selectively and non-covalently with any protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | Q69Z66 (/ISO) |
|
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q5VVJ2 (/IDA) |
|
Thiol-dependent ubiquitinyl hydrolase activity GO:0036459
Catalysis of the thiol-dependent hydrolysis of an ester, thioester, amide, peptide or isopeptide bond formed by the C-terminal glycine of ubiquitin.
|
1 | Q69Z66 (/ISO) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q5VVJ2 (/IDA) |
|
Histone binding GO:0042393
Interacting selectively and non-covalently with a histone, any of a group of water-soluble proteins found in association with the DNA of plant and animal chromosomes. They are involved in the condensation and coiling of chromosomes during cell division and have also been implicated in nonspecific suppression of gene activity.
|
1 | Q69Z66 (/ISO) |
There are 13 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Monoubiquitinated histone H2A deubiquitination GO:0035522
The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q5VVJ2 (/IMP) |
|
Chromatin remodeling GO:0006338
Dynamic structural changes to eukaryotic chromatin occurring throughout the cell division cycle. These changes range from the local changes necessary for transcriptional regulation to global changes necessary for chromosome segregation.
|
1 | Q69Z66 (/ISO) |
|
Protein deubiquitination GO:0016579
The removal of one or more ubiquitin groups from a protein.
|
1 | Q5VVJ2 (/TAS) |
|
Regulation of cell migration GO:0030334
Any process that modulates the frequency, rate or extent of cell migration.
|
1 | Q69Z66 (/IMP) |
|
Monoubiquitinated histone H2A deubiquitination GO:0035522
The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.
|
1 | Q5VVJ2 (/IMP) |
|
Monoubiquitinated histone H2A deubiquitination GO:0035522
The removal of the ubiquitin group from a monoubiquitinated histone H2A protein.
|
1 | Q69Z66 (/ISO) |
|
Pigmentation GO:0043473
The accumulation of pigment in an organism, tissue or cell, either by increased deposition or by increased number of cells.
|
1 | Q69Z66 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q5VVJ2 (/IMP) |
|
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
|
1 | Q69Z66 (/ISO) |
|
Regulation of hair follicle development GO:0051797
Any process that modulates the frequency, rate or extent of hair follicle development.
|
1 | Q69Z66 (/IMP) |
There are 8 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
5 | A0JMR6 (/ISS) B6MUN4 (/ISS) Q5F3F2 (/ISS) Q5RGA4 (/ISS) Q69Z66 (/ISS) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q5VVJ2 (/IDA) |
|
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
|
1 | Q69Z66 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q5VVJ2 (/IDA) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q69Z66 (/ISO) |
|
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
|
1 | Q5VVJ2 (/TAS) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q5VVJ2 (/IDA) |
|
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
|
1 | Q69Z66 (/ISO) |