The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 124609: Trihelix transcription factor GT-2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 10 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
10 Q39117 (/ISS) Q39117 (/ISS) Q700D8 (/ISS) Q8H181 (/ISS) Q9C6K3 (/ISS) Q9C6K3 (/ISS) Q9C882 (/ISS) Q9C882 (/ISS) Q9FGJ1 (/ISS) Q9LZS0 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
3 Q9C882 (/IDA) Q9C882 (/IDA) Q9LZS0 (/IDA)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 Q9C882 (/ISS) Q9C882 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9C882 (/IDA) Q9C882 (/IDA)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 Q9C6K3 (/IPI) Q9C6K3 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q9C6K3 (/IPI) Q9C6K3 (/IPI)
Enhancer sequence-specific DNA binding GO:0001158
Interacting selectively and non-covalently with a specific sequence of DNA that is part of an enhancer, a transcription regulatory region that is somewhat distal from the core promoter and which enhances transcription from that promoter.
1 Q8H181 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q9LZS0 (/TAS)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 Q8H181 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 Q9LZS0 (/IDA)

There are 24 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
6 Q700D8 (/TAS) Q8H181 (/TAS) Q9C6K3 (/TAS) Q9C6K3 (/TAS) Q9FGJ1 (/TAS) Q9LZS0 (/TAS)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
2 Q9C882 (/IDA) Q9C882 (/IDA)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Response to water deprivation GO:0009414
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a water deprivation stimulus, prolonged deprivation of water.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Trichome morphogenesis GO:0010090
The process in which the structures of a hair cell (trichome) cell are generated and organized. This process occurs while the initially relatively unspecialized epidermal cell is acquiring the specialized features of a hair cell. An example of this process is found in Arabidopsis thaliana.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Mucilage biosynthetic process GO:0010192
The chemical reactions and pathways resulting in the formation of mucilage, a gelatinous substance secreted by plants.
2 Q9C6K3 (/IMP) Q9C6K3 (/IMP)
Glucosinolate metabolic process GO:0019760
The chemical reactions and pathways involving glucosinolates, substituted thioglucosides found in rapeseed products and related cruciferae. They are metabolized to a variety of toxic products which are most likely the cause of hepatocytic necrosis in animals and humans.
2 Q9C6K3 (/IMP) Q9C6K3 (/IMP)
Negative regulation of cell growth GO:0030308
Any process that stops, prevents, or reduces the frequency, rate, extent or direction of cell growth.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Negative regulation of DNA endoreduplication GO:0032876
Any process that stops, prevents, or reduces the frequency, rate or extent of DNA endoreduplication.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Cellular response to water deprivation GO:0042631
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of water.
2 Q9C882 (/IEP) Q9C882 (/IEP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q9C882 (/IDA) Q9C882 (/IDA)
Regulation of stomatal complex patterning GO:2000037
Any process that modulates the frequency, rate or extent of stomatal complex patterning.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Regulation of stomatal complex development GO:2000038
Any process that modulates the frequency, rate or extent of stomatal complex development.
2 Q9C882 (/IMP) Q9C882 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9LZS0 (/IDA)
Regulation of flower development GO:0009909
Any process that modulates the frequency, rate or extent of flower development.
1 Q9LZS0 (/IMP)
Polar nucleus fusion GO:0010197
The merging of the polar nuclei, the two nuclei contained within the same cell that are created from the mitotic division of the megaspore during angiosperm reproduction. Polar nuclear fusion takes place in the ovule, forming in the fusion nucleus and giving rise to the endosperm when fertilized.
1 Q700D8 (/IMP)
Response to chitin GO:0010200
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
1 Q9LZS0 (/IEP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q8H181 (/IDA)
Negative regulation of organ growth GO:0046621
Any process that stops, prevents, or reduces the frequency, rate or extent of growth of an organ of an organism.
1 Q9LZS0 (/IMP)
Petal development GO:0048441
The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
1 Q9LZS0 (/IGI)
Petal development GO:0048441
The process whose specific outcome is the progression of the petal over time, from its formation to the mature structure.
1 Q9LZS0 (/IMP)
Sepal development GO:0048442
The process whose specific outcome is the progression of the sepal over time, from its formation to the mature structure.
1 Q9LZS0 (/IGI)
Establishment of petal orientation GO:0048498
The process that determines the orientation of petals with reference to the central axis.
1 Q9LZS0 (/IMP)
Perianth development GO:0090428
The process whose specific outcome is the progression of the perianth over time, from its formation to the mature structure. The perianth is a collective phyllome structure composed of two or more petals, sepals, or tepals.
1 Q9LZS0 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 Q8H181 (/IDA) Q9C882 (/IDA) Q9C882 (/IDA) Q9LZS0 (/IDA)