The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 124229: Putative WUSCHEL-related homeobox 2

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 5 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
14 B3H5D3 (/ISS) O81788 (/ISS) Q6X7J4 (/ISS) Q6X7J5 (/ISS) Q6X7K0 (/ISS) Q6X7K1 (/ISS) Q8GY25 (/ISS) Q8H1D2 (/ISS) Q9FFK0 (/ISS) Q9LM83 (/ISS)
(4 more)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
4 Q33DK0 (/IPI) Q33DK1 (/IPI) Q8H1D2 (/IPI) Q9SB92 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
3 Q6X7J4 (/IPI) Q8H1D2 (/IPI) Q9LM84 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
2 Q6X7J4 (/IPI) Q9LM84 (/IPI)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q9SIB4 (/TAS)

There are 44 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
3 Q6X7J9 (/IMP) Q9LM84 (/IMP) Q9ZVF5 (/IMP)
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
2 Q6X7J9 (/IMP) Q9LM84 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
2 Q6X7J5 (/IGI) Q6X7K1 (/IGI)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
2 Q6X7J4 (/IMP) Q6X7J5 (/IMP)
Cotyledon development GO:0048825
The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
2 Q6X7J5 (/IGI) Q6X7K1 (/IGI)
Cotyledon development GO:0048825
The process whose specific outcome is the progression of the cotyledon over time, from its formation to the mature structure. The cotyledon is the modified leaf (seed leaf), found as part of the embryo in plant seeds. It is involved in either storage or absorption of food reserves. Dicotyledonous seeds contain two cotyledons, while monocotyledonous seeds contain only one. The cotyledons may appear above ground and show photosynthetic activity in the seedling.
2 Q6X7J5 (/IMP) Q6X7K1 (/IMP)
Cotyledon boundary formation GO:0090451
The process in which boundaries between a cotyledon and the surrounding tissue are established and maintained.
2 Q6X7J5 (/IGI) Q6X7K1 (/IGI)
Plant organ development GO:0099402
Development of a plant organ, a multi-tissue plant structure that forms a functional unit.
2 Q6X7K0 (/IGI) Q9SIB4 (/IGI)
Vasculature development GO:0001944
The process whose specific outcome is the progression of the vasculature over time, from its formation to the mature structure. The vasculature is an interconnected tubular multi-tissue structure that contains fluid that is actively transported around the organism.
1 Q6X7J9 (/IEP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9SB92 (/TAS)
Signal transduction GO:0007165
The cellular process in which a signal is conveyed to trigger a change in the activity or state of a cell. Signal transduction begins with reception of a signal (e.g. a ligand binding to a receptor or receptor activation by a stimulus such as light), or for signal transduction in the absence of ligand, signal-withdrawal or the activity of a constitutively active receptor. Signal transduction ends with regulation of a downstream cellular process, e.g. regulation of transcription or regulation of a metabolic process. Signal transduction covers signaling from receptors located on the surface of the cell and signaling via molecules located within the cell. For signaling between cells, signal transduction is restricted to events at and within the receiving cell.
1 Q6X7J9 (/IEP)
Cell proliferation GO:0008283
The multiplication or reproduction of cells, resulting in the expansion of a cell population.
1 Q9SIB4 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q6X7J4 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 Q8H1D2 (/IEP)
Auxin-activated signaling pathway GO:0009734
A series of molecular signals generated by the binding of the plant hormone auxin to a receptor, and ending with modulation of a downstream cellular process, e.g. transcription.
1 B3H5D3 (/IEP)
Embryo development ending in seed dormancy GO:0009793
The process whose specific outcome is the progression of the embryo over time, from zygote formation to the end of seed dormancy. An example of this process is found in Arabidopsis thaliana.
1 Q6X7J5 (/IGI)
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
1 Q6X7K1 (/IMP)
Flower development GO:0009908
The process whose specific outcome is the progression of the flower over time, from its formation to the mature structure. The flower is the reproductive structure in a plant, and its development begins with the transition of the vegetative or inflorescence meristem into a floral meristem.
1 Q9SIB4 (/IMP)
Longitudinal axis specification GO:0009942
The establishment, maintenance and elaboration of the longitudinal axis. In plants, this is the axis that runs from the shoot to the root.
1 Q6X7K1 (/IMP)
Adaxial/abaxial axis specification GO:0009943
The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
1 Q9SIB4 (/IMP)
Centrolateral axis specification GO:0009947
The establishment, maintenance and elaboration of the centrolateral axis. In plants, this axis is duplicated and runs from the midrib to the margin of the leaf.
1 Q9SIB4 (/IMP)
Leaf morphogenesis GO:0009965
The process in which the anatomical structures of the leaf are generated and organized.
1 Q9ZVF5 (/IMP)
Procambium histogenesis GO:0010067
The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.
1 Q6X7J9 (/IMP)
Primary shoot apical meristem specification GO:0010072
The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.
1 Q9LM84 (/IMP)
Regulation of meristem growth GO:0010075
Any process involved in maintaining the size and shape of a meristem.
1 Q6X7J4 (/IMP)
Maintenance of root meristem identity GO:0010078
The process in which an organism retains a population of root meristem cells, preventing the commitment of all stem cell progeny to a differentiated cell fate.
1 Q8H1D2 (/IMP)
Phloem or xylem histogenesis GO:0010087
The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
1 Q9LM84 (/IMP)
Apical cell fate commitment GO:0010654
The process in which the developmental fate of a cell becomes restricted such that it will develop into an apical cell. The apical cell is the upper cell formed after the first division of the zygote.
1 Q6X7K1 (/IMP)
Stipule development GO:0010865
The process whose specific outcome is the progression of the stipule over time, from its formation to the mature structure. A stipule is one of (usually) a pair of appendages at the bases of leaves in many broad-leaved angiosperms.
1 Q9SIB4 (/IMP)
Cell growth GO:0016049
The process in which a cell irreversibly increases in size over time by accretion and biosynthetic production of matter similar to that already present.
1 Q9ZVF5 (/IMP)
Stem cell population maintenance GO:0019827
The process by which an organism or tissue maintains a population of stem cells of a single type. This can be achieved by a number of mechanisms: stem cell asymmetric division maintains stem cell numbers; stem cell symmetric division increases them; maintenance of a stem cell niche maintains the conditions for commitment to the stem cell fate for some types of stem cell; stem cells may arise de novo from other cell types.
1 Q9SB92 (/IMP)
Establishment of cell polarity GO:0030010
The specification and formation of anisotropic intracellular organization or cell growth patterns.
1 Q6X7J5 (/IMP)
Embryo sac morphogenesis GO:0048314
The process in which the anatomical structures of the embryo sac are generated and organized. The embryo sac develops from the megaspore in heterosporous plants.
1 Q9ZVF5 (/IMP)
Leaf development GO:0048366
The process whose specific outcome is the progression of the leaf over time, from its formation to the mature structure.
1 Q9ZVF5 (/IMP)
Floral organ development GO:0048437
The process whose specific outcome is the progression of the floral organ over time, from its formation to the mature structure.
1 Q9ZVF5 (/IMP)
Petal morphogenesis GO:0048446
The process in which the anatomical structures of the petal are generated and organized.
1 Q9ZVF5 (/IMP)
Plant ovule morphogenesis GO:0048482
The process in which the anatomical structures of the ovule are generated and organized. The ovule is the structure in seed plants enclosing the female gametophyte, and is composed of the nucellus, one or two integuments, and the funiculus; it develops into the seed.
1 Q9ZVF5 (/IMP)
Anther development GO:0048653
The process whose specific outcome is the progression of the anther over time, from its formation to the mature structure.
1 Q9SB92 (/IMP)
Adventitious root development GO:0048830
The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
1 Q8GY25 (/IGI)
Adventitious root development GO:0048830
The process whose specific outcome is the progression of adventitious root over time, from its formation to the mature structure. Adventitious roots are post-embryonic roots that develop from the plant shoot.
1 B3H5D3 (/IMP)
Cell division GO:0051301
The process resulting in division and partitioning of components of a cell to form more cells; may or may not be accompanied by the physical separation of a cell into distinct, individually membrane-bounded daughter cells.
1 Q6X7J9 (/IEP)
Stomium development GO:0080166
The process whose specific outcome is the progression of the stomium over time, from its formation to the mature structure. A stomium is a fissure or pore in the anther lobe through which the pollen is released.
1 Q9SB92 (/IMP)
Response to karrikin GO:0080167
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a karrikin stimulus. Karrikins are signaling molecules in smoke from burning vegetation that trigger seed germination for many angiosperms (flowering plants).
1 Q6X7K1 (/IEP)
Positive regulation of stem cell population maintenance GO:1902459
Any process that activates or increases the frequency, rate or extent of stem cell population maintenance.
1 Q8H1D2 (/IMP)

There are 4 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
5 Q6X7J4 (/IDA) Q6X7J5 (/IDA) Q6X7J9 (/IDA) Q9SIB4 (/IDA) Q9ZVF5 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q6X7J4 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q6X7K0 (/IDA)
Primary endosperm nucleus GO:0048353
Nucleus resulting from the fusion of the male gamete and two polar nuclei in the central cell of the embryo sac.
1 Q9ZVF5 (/IDA)