The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Homeodomain-like
".
FunFam 124137: Fis family transcriptional regulator
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 17 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
2 | P0A6R3 (/IDA) Q74EF9 (/IDA) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
2 | P0A6R3 (/IPI) Q74EF9 (/IPI) |
|
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
2 | P64127 (/ISS) Q83EI3 (/ISS) |
|
Transcription regulatory region sequence-specific DNA binding GO:0000976
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls transcription of that section of the DNA. The transcribed region might be described as a gene, cistron, or operon.
|
1 | Q74EF9 (/EXP) |
|
Bacterial-type RNA polymerase core promoter sequence-specific DNA binding GO:0000985
Interacting selectively and non-covalently with a specific DNA sequence in a bacterial-type RNA polymerase core promoter, the region composed of the transcription start site and binding sites for transcription factors of the basal transcription machinery, in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | P0A6R3 (/IMP) |
|
Transcriptional activator activity, bacterial-type RNA polymerase core promoter proximal region sequence-specific binding GO:0001140
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for a bacterial-type RNA polymerase in order to increase transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | P0A6R3 (/IMP) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q74EF9 (/EXP) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q74EF9 (/IDA) |
|
Bacterial-type RNA polymerase transcriptional activator activity, sequence-specific DNA binding GO:0001216
Interacting selectively and non-covalently with a specific DNA sequence in order to activate or increase the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | Q74EF9 (/IPI) |
|
Bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | P0A6R3 (/IDA) |
|
Bacterial-type RNA polymerase transcriptional repressor activity, sequence-specific DNA binding GO:0001217
Interacting selectively and non-covalently with a specific DNA sequence in order to stop, prevent, or reduce the frequency, rate or extent of transcription by bacterial-type RNA polymerase. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
|
1 | P0A6R3 (/IPI) |
|
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
|
1 | P0A6R3 (/IDA) |
|
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
|
1 | P0A6R3 (/IPI) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P0A6R3 (/IDA) |
|
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
|
1 | P0A6R3 (/IMP) |
|
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
|
1 | P0A6R3 (/IDA) |
|
Sequence-specific DNA binding, bending GO:0044374
The activity of binding selectively and non-covalently to DNA in a sequence-specific manner and distorting the original structure of DNA, typically a straight helix, into a bend, or increasing the bend if the original structure was intrinsically bent due to its sequence.
|
1 | P0A6R3 (/IMP) |
There are 7 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
2 | P64127 (/ISS) Q83EI3 (/ISS) |
|
Transcription from bacterial-type RNA polymerase promoter GO:0001121
The synthesis of RNA from a DNA template by a bacterial-type RNA polymerase, originating at a bacterial-type promoter.
|
1 | P0A6R3 (/IMP) |
|
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P0A6R3 (/IDA) |
|
Provirus excision GO:0032359
The molecular events that lead to the excision of a viral genome from the host genome.
|
1 | P0A6R3 (/IMP) |
|
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
|
1 | P57902 (/EXP) |
|
Positive regulation of DNA recombination GO:0045911
Any process that activates or increases the frequency, rate or extent of DNA recombination.
|
1 | P0A6R3 (/IMP) |
|
Single-species submerged biofilm formation GO:0090609
A process in which planktonically growing microorganisms of the same species aggregate and grow on solid substrates under the flow of a liquid and produce extracellular polymers that facilitate attachment and matrix formation, resulting in a change in the organisms' growth rate and gene transcription.
|
1 | D3GYQ2 (/IMP) |
There are 6 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
| GO Term | Annotations | Evidence |
|---|---|---|
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
2 | P0A6R3 (/IDA) Q74EF9 (/IDA) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
2 | P0A6R3 (/IPI) Q74EF9 (/IPI) |
|
Cytoplasmic nucleosome GO:0000787
A complex comprised of DNA wound around a multisubunit core and associated proteins, which forms the primary packing unit of DNA in the cytoplasm into higher order structures.
|
1 | P0A6R3 (/IDA) |
|
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
|
1 | P0A6R3 (/IDA) |
|
Invertasome GO:0031421
A complex formed by a recombinase, a regulatory protein, and the DNA sequences bound by each protein; catalyzes a reversible site-specific recombination reaction that results in the alternate expression of one or more genes in various contexts.
|
1 | P0A6R3 (/IMP) |
|
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
|
1 | Q74EF9 (/EXP) |
