The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Homeodomain-like
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 123506: Class III homeodomain-leucine zipper

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 6 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
5 B3H4G8 (/ISS) O04291 (/ISS) O04292 (/ISS) Q39123 (/ISS) Q9SE43 (/ISS)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 O04291 (/ISS) O04292 (/ISS)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 B3H4G8 (/TAS)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 O04292 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 Q9SE43 (/IPI)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q9SE43 (/IPI)

There are 22 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Meristem initiation GO:0010014
Initiation of a region of tissue in a plant that is composed of one or more undifferentiated cells capable of undergoing mitosis and differentiation, thereby effecting growth and development of a plant by giving rise to more meristem or specialized tissue.
5 B3H4G8 (/IMP) O04291 (/IMP) O04292 (/IMP) Q39123 (/IMP) Q9SE43 (/IMP)
Determination of bilateral symmetry GO:0009855
The establishment of an organism's body plan or part of an organism with respect to a single longitudinal plane. The pattern can either be symmetric, such that the halves are mirror images, or asymmetric where the pattern deviates from this symmetry.
4 B3H4G8 (/IMP) O04291 (/IMP) O04292 (/IMP) Q9SE43 (/IMP)
Polarity specification of adaxial/abaxial axis GO:0009944
The process resulting in the establishment of polarity along the adaxial/abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
3 O04291 (/IMP) O04292 (/IMP) Q9SE43 (/IMP)
Primary shoot apical meristem specification GO:0010072
The specification of the meristem which will give rise to all post-embryonic above-ground structures of the plant as well as the non-root below-ground structures, such as rhizomes and tubers.
3 O04291 (/IMP) O04292 (/IMP) Q39123 (/IMP)
Integument development GO:0080060
The process whose specific outcome is the progression of the integument over time, from its formation to the mature structure. Integument is one of the layers of tissue that usually covers the ovule, enveloping the nucellus and forming the micropyle at the apex.
3 B3H4G8 (/IGI) O04291 (/IGI) O04292 (/IGI)
Xylem development GO:0010089
The formation of the principal water-conducting tissue of a vascular plant.
2 Q39123 (/IMP) Q9SE43 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q39123 (/IMP)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 Q39123 (/IEP)
Embryonic pattern specification GO:0009880
The process that results in the patterns of cell differentiation that will arise in an embryo.
1 O04292 (/IGI)
Adaxial/abaxial axis specification GO:0009943
The establishment, maintenance and elaboration of the adaxial / abaxial axis. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
1 O04292 (/IMP)
Adaxial/abaxial pattern specification GO:0009955
The regionalization process in which differences in cell differentiation along the adaxial/abaxial are generated. Adaxial refers to being situated toward an axis of an anatomical structure. Abaxial refers to being situated away from an axis of an anatomical structure.
1 O04291 (/IMP)
Radial pattern formation GO:0009956
The regionalization process that results in defined areas around a point in which specific types of cell differentiation will occur.
1 Q9SE43 (/IMP)
Leaf morphogenesis GO:0009965
The process in which the anatomical structures of the leaf are generated and organized.
1 B3H4G8 (/IMP)
Xylem and phloem pattern formation GO:0010051
The regionalization process that gives rise to the patterning of the conducting tissues. An example of this process is found in Arabidopsis thaliana.
1 Q9SE43 (/IMP)
Procambium histogenesis GO:0010067
The formation of the primary meristem or meristematic tissue that gives rise to the primary vascular tissue.
1 Q39123 (/IEP)
Meristem maintenance GO:0010073
Any process involved in maintaining the identity, size and shape of a meristem.
1 B3H4G8 (/TAS)
Regulation of meristem growth GO:0010075
Any process involved in maintaining the size and shape of a meristem.
1 B3H4G8 (/IMP)
Phloem or xylem histogenesis GO:0010087
The process whose specific outcome is the progression of phloem and/or xylem over time, from formation to the mature structure. An example of this process is found in Arabidopsis thaliana.
1 B3H4G8 (/IMP)
Cell differentiation GO:0030154
The process in which relatively unspecialized cells, e.g. embryonic or regenerative cells, acquire specialized structural and/or functional features that characterize the cells, tissues, or organs of the mature organism or some other relatively stable phase of the organism's life history. Differentiation includes the processes involved in commitment of a cell to a specific fate and its subsequent development to the mature state.
1 Q9SE43 (/IMP)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
1 Q39123 (/IMP)
Determination of dorsal identity GO:0048263
Determination of the identity of part of an organism or organ where those parts are of the type that occur in the dorsal region. Identity is considered to be the aggregate of characteristics by which a structure is recognized.
1 B3H4G8 (/IMP)
Plant organ morphogenesis GO:1905392
The developmental process by which a plant organ is generated and organized.
1 B3H4G8 (/IMP)

There are 1 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
4 B3H4G8 (/IDA) O04291 (/IDA) Q39123 (/IDA) Q9SE43 (/IDA)