The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:
"Phosphatase 2C, C-terminal domain suprefamily
".
FunFam 44: Alphabet, isoform E
Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.
There are 2 GO terms relating to "molecular function"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Protein serine/threonine phosphatase activity GO:0004722
Catalysis of the reaction: protein serine phosphate + H2O = protein serine + phosphate, and protein threonine phosphate + H2O = protein threonine + phosphate.
|
3 | Q8IMK7 (/NAS) Q961C5 (/NAS) Q9VAK1 (/NAS) |
Phosphatase activity GO:0016791
Catalysis of the hydrolysis of phosphoric monoesters, releasing inorganic phosphate.
|
3 | Q8IMK7 (/IDA) Q961C5 (/IDA) Q9VAK1 (/IDA) |
There are 23 GO terms relating to "biological process"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.
GO Term | Annotations | Evidence |
---|---|---|
Mitotic cell cycle GO:0000278
Progression through the phases of the mitotic cell cycle, the most common eukaryotic cell cycle, which canonically comprises four successive phases called G1, S, G2, and M and includes replication of the genome and the subsequent segregation of chromosomes into daughter cells. In some variant cell cycles nuclear replication or nuclear division may not be followed by cell division, or G1 and G2 phases may be absent.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Compound eye morphogenesis GO:0001745
The morphogenetic process in which the anatomical structures of the compound eye are generated and organized. The adult compound eye is a precise assembly of 700-800 ommatidia. Each ommatidium is composed of 20 cells, identified by cell type and position. An example of compound eye morphogenesis is found in Drosophila melanogaster.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Protein dephosphorylation GO:0006470
The process of removing one or more phosphoric residues from a protein.
|
3 | Q8IMK7 (/NAS) Q961C5 (/NAS) Q9VAK1 (/NAS) |
Response to oxidative stress GO:0006979
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Dorsal closure GO:0007391
The process during Drosophila embryogenesis whereby the ectodermal cells of the lateral epithelium stretch in a coordinated fashion to internalize the amnioserosa cells and close the embryo dorsally.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Imaginal disc-derived wing morphogenesis GO:0007476
The process in which the anatomical structures of the imaginal disc-derived wing are generated and organized. The wing is an appendage modified for flying.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Response to UV-C GO:0010225
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a UV-C radiation stimulus. UV-C radiation (UV-C light) spans the wavelengths 100 to 280 nm.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Dephosphorylation GO:0016311
The process of removing one or more phosphoric (ester or anhydride) residues from a molecule.
|
3 | Q8IMK7 (/IDA) Q961C5 (/IDA) Q9VAK1 (/IDA) |
Negative regulation of stress-activated MAPK cascade GO:0032873
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the stress-activated MAPK cascade.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Negative regulation of MAP kinase activity GO:0043407
Any process that stops, prevents, or reduces the frequency, rate or extent of MAP kinase activity.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Positive regulation of R7 cell differentiation GO:0045678
Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Positive regulation of R7 cell differentiation GO:0045678
Any process that activates or increases the frequency, rate or extent of R7 cell differentiation.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Negative regulation of JNK cascade GO:0046329
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the JNK cascade.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Imaginal disc fusion, thorax closure GO:0046529
The joining of the parts of the wing imaginal discs, giving rise to the adult thorax.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Negative regulation of Ras protein signal transduction GO:0046580
Any process that stops, prevents, or reduces the frequency, rate or extent of Ras protein signal transduction.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Negative regulation of stress-activated protein kinase signaling cascade GO:0070303
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Negative regulation of stress-activated protein kinase signaling cascade GO:0070303
Any process that stops, prevents, or reduces the frequency, rate or extent of signaling via the stress-activated protein kinase signaling cascade.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
Negative regulation of ERK1 and ERK2 cascade GO:0070373
Any process that stops, prevents, or reduces the frequency, rate or extent of signal transduction mediated by the ERK1 and ERK2 cascade.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Regulation of p38MAPK cascade GO:1900744
Any process that modulates the frequency, rate or extent of p38MAPK cascade.
|
3 | Q8IMK7 (/IGI) Q961C5 (/IGI) Q9VAK1 (/IGI) |
Response to paraquat GO:1901562
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a paraquat stimulus.
|
3 | Q8IMK7 (/IMP) Q961C5 (/IMP) Q9VAK1 (/IMP) |
There are 0 GO terms relating to "cellular component"
The search results have been sorted with the annotations that are found most frequently at the top of the
list. The results can be filtered by typing text into the search box at the top of the table.