The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 265275: Transcriptional regulator, GntR family

There are 4 EC terms in this cluster

Please note: EC annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

Note: The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.

EC Term Annotations Evidence
Argininosuccinate lyase. [EC: 4.3.2.1]
2-(N(omega)-L-arginino)succinate = fumarate + L-arginine.
    8 N9XHB4 N9XHB4 N9ZG55 N9ZG55 R0BY86 R0BY86 R5F6C4 R5F6C4
    Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208. [EC: 2.7.1.69]
      4 D2EIM4 D2EIM4 E0NEM1 E0NEM1
      Peptide deformylase. [EC: 3.5.1.88]
      Formyl-L-methionyl peptide + H(2)O = formate + methionyl peptide.
      • Requires at least a dipeptide for an efficient rate of reaction.
      • N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.
      • Differs in substrate specificity from EC 3.5.1.27 and EC 3.5.1.31.
      2 J1S5X5 J1S5X5
      Threonine--tRNA ligase. [EC: 6.1.1.3]
      ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + L-threonyl-tRNA(Thr).
        2 A8T1P3 A8T1P3