The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 265148: Heat shock transcription factor

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 79 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
22 G5EFT5 (/ISS) O22230 (/ISS) O49403 (/ISS) O80982 (/ISS) O81821 (/ISS) P41151 (/ISS) Q1PDN3 (/ISS) Q8GYY1 (/ISS) Q94BZ5 (/ISS) Q96320 (/ISS)
(12 more)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
18 A0A060W590 (/IDA) A0A096MK39 (/IDA) D0VYS2 (/IDA) F1Q5S8 (/IDA) F1QJY6 (/IDA) F1R0H1 (/IDA) F6P697 (/IDA) P22813 (/IDA) P38529 (/IDA) P38531 (/IDA)
(8 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
9 O81821 (/IDA) P22813 (/IDA) P38529 (/IDA) P38531 (/IDA) P38532 (/IDA) P38533 (/IDA) P41151 (/IDA) Q00613 (/IDA) Q8GYY1 (/IDA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
9 O14283 (/IPI) O49403 (/IPI) O80982 (/IPI) P22813 (/IPI) P41151 (/IPI) Q00613 (/IPI) Q03933 (/IPI) Q6Q4G5 (/IPI) Q9LQM7 (/IPI)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
6 A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) P38533 (/IDA) Q76M53 (/IDA)
Core promoter sequence-specific DNA binding GO:0001046
Interacting selectively and non-covalently with a sequence of DNA that is part of a core promoter region composed of the transcription start site and binding sites for the basal transcription machinery. The transcribed region might be described as a gene, cistron, or operon.
4 A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
4 P22813 (/IPI) Q338B0 (/IPI) Q6Q4G5 (/IPI) Q7XHZ0 (/IPI)
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
3 O14283 (/IDA) Q00613 (/IDA) Q02953 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
3 P10961 (/IDA) P22813 (/IDA) P38889 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
3 Q00613 (/TAS) Q03933 (/TAS) Q9ULV5 (/TAS)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
3 F1MAF1 (/IDA) G5EFT5 (/IDA) Q00613 (/IDA)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
RNA polymerase II core promoter sequence-specific DNA binding GO:0000979
Interacting selectively and non-covalently with the regulatory region composed of the transcription start site and binding sites for transcription factors of the RNA polymerase II basal transcription machinery.
2 P38532 (/IDA) P38533 (/IDA)
Core promoter proximal region sequence-specific DNA binding GO:0000987
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to the core promoter. The transcribed region might be described as a gene, cistron, or operon.
2 Q76M53 (/IDA) Q76M54 (/IDA)
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding GO:0001162
Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.
2 Q00613 (/IDA) Q03933 (/IDA)
RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding GO:0001162
Interacting selectively and non-covalently with an RNA polymerase II intronic DNA sequence that regulates the transcription of the transcript it is contained within.
2 P38532 (/ISO) P38533 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P10961 (/IMP) P22121 (/IMP)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
2 P38529 (/ISS) Q08DJ8 (/ISS)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
2 O81821 (/IMP) P38889 (/IMP)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
2 F1MAF1 (/IDA) Q00613 (/IDA)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
2 D0VYS2 (/IDA) Q00613 (/IDA)
SUMO binding GO:0032183
Interacting selectively and non-covalently with the small ubiquitin-like protein SUMO.
2 A0A060W590 (/IMP) Q8AWA0 (/IMP)
Activating transcription factor binding GO:0033613
Interacting selectively and non-covalently with an activating transcription factor, any protein whose activity is required to initiate or upregulate transcription.
2 Q76M53 (/IDA) Q76M54 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
2 P38529 (/ISS) Q08DJ8 (/ISS)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Translation elongation factor binding GO:0061770
Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 P38889 (/IDA)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 P38889 (/IMP)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 C8V7M0 (/ISA)
Phosphorelay response regulator activity GO:0000156
Responds to a phosphorelay sensor to initiate a change in cell state or activity. The activity of the response regulator is regulated by transfer of a phosphate from a histidine residue in the sensor, to an aspartate residue in the response regulator. Many but not all response regulators act as transcriptional regulators to elicit a response.
1 Q5A4X5 (/ISS)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 Q03933 (/IDA)
RNA polymerase II regulatory region sequence-specific DNA binding GO:0000977
Interacting selectively and non-covalently with a specific sequence of DNA that is part of a regulatory region that controls the transcription of a gene or cistron by RNA polymerase II.
1 P38533 (/ISO)
RNA polymerase II core promoter proximal region sequence-specific DNA binding GO:0000978
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II.
1 P38532 (/ISO)
RNA polymerase II transcription factor activity, sequence-specific DNA binding GO:0000981
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription by RNA polymerase II. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q6FTT1 (/IMP)
Transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0000982
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
1 Q02953 (/IDA)
Transcription factor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0000982
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to modulate transcription by RNAP II.
1 O14283 (/NAS)
Transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001077
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 Q02953 (/IMP)
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q00613 (/IDA)
Transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding GO:0001078
Interacting selectively and non-covalently with a sequence of DNA that is in cis with and relatively close to a core promoter for RNA polymerase II (RNAP II) in order to stop, prevent, or reduce the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P38532 (/ISO)
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 Q03933 (/IDA)
Transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding GO:0001228
Interacting selectively and non-covalently with a sequence of DNA that is in the transcription regulatory region for RNA polymerase II (RNAP II) in order to activate or increase the frequency, rate or extent of transcription from the RNAP II promoter.
1 P38533 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P38532 (/ISO)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 P22813 (/TAS)
Chromatin binding GO:0003682
Interacting selectively and non-covalently with chromatin, the network of fibers of DNA, protein, and sometimes RNA, that make up the chromosomes of the eukaryotic nucleus during interphase.
1 P38532 (/IDA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 P38889 (/IPI)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q6FTT1 (/ISA)
Transcription factor activity, sequence-specific DNA binding GO:0003700
Interacting selectively and non-covalently with a specific DNA sequence in order to modulate transcription. The transcription factor may or may not also interact selectively with a protein or macromolecular complex.
1 Q5AQ33 (/ISO)
Transcription coactivator activity GO:0003713
Interacting selectively and non-covalently with a activating transcription factor and also with the basal transcription machinery in order to increase the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between activating transcription factors and the basal transcription machinery.
1 Q03933 (/TAS)
Transcription corepressor activity GO:0003714
Interacting selectively and non-covalently with a repressing transcription factor and also with the basal transcription machinery in order to stop, prevent, or reduce the frequency, rate or extent of transcription. Cofactors generally do not bind the template nucleic acid, but rather mediate protein-protein interactions between repressive transcription factors and the basal transcription machinery.
1 Q9ULV5 (/TAS)
Calmodulin binding GO:0005516
Interacting selectively and non-covalently with calmodulin, a calcium-binding protein with many roles, both in the calcium-bound and calcium-free states.
1 G5EFT5 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 Q00613 (/IPI)
Protein kinase binding GO:0019901
Interacting selectively and non-covalently with a protein kinase, any enzyme that catalyzes the transfer of a phosphate group, usually from ATP, to a protein substrate.
1 P38532 (/ISO)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 Q9ULV5 (/IPI)
Protein phosphatase binding GO:0019903
Interacting selectively and non-covalently with any protein phosphatase.
1 Q9R0L1 (/ISO)
Heat shock protein binding GO:0031072
Interacting selectively and non-covalently with a heat shock protein, any protein synthesized or activated in response to heat shock.
1 P38532 (/ISO)
Chromatin DNA binding GO:0031490
Interacting selectively and non-covalently with DNA that is assembled into chromatin.
1 P38532 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 Q00613 (/IDA)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P38532 (/ISO)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
1 O49403 (/IPI)
Sequence-specific DNA binding GO:0043565
Interacting selectively and non-covalently with DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA e.g. promotor binding or rDNA binding.
1 P38532 (/ISO)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
1 Q00613 (/IDA)
Protein self-association GO:0043621
Interacting selectively and non-covalently with a domain within the same polypeptide.
1 P38532 (/ISO)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 Q6FTT1 (/IDA)
Transcription regulatory region DNA binding GO:0044212
Interacting selectively and non-covalently with a DNA region that regulates the transcription of a region of DNA, which may be a gene, cistron, or operon. Binding may occur as a sequence specific interaction or as an interaction observed only once a factor has been recruited to the DNA by other factors.
1 O80982 (/IPI)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 Q00613 (/IDA)
Protein heterodimerization activity GO:0046982
Interacting selectively and non-covalently with a nonidentical protein to form a heterodimer.
1 P38532 (/ISO)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
1 Q00613 (/IDA)
Hsp90 protein binding GO:0051879
Interacting selectively and non-covalently with Hsp90 proteins, any of a group of heat shock proteins around 90kDa in size.
1 P38532 (/ISO)
Translation elongation factor binding GO:0061770
Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.
1 Q00613 (/IDA)
Translation elongation factor binding GO:0061770
Interacting selectively and non-covalently with a translation elongation factor, any polypeptide factor involved in the peptide elongation in ribosome-mediated translation.
1 P38532 (/ISO)
STAT family protein binding GO:0097677
Interacting selectively and non-covalently with any member of the signal transducers and activators of transcription (STAT) protein family. STATs are, as the name indicates, both signal transducers and transcription factors. STATs are activated by cytokines and some growth factors and thus control important biological processes including cell growth, cell differentiation, apoptosis and immune responses.
1 F1MAF1 (/IPI)
Sequence-specific single stranded DNA binding GO:0098847
Interacting selectively and non-covalently with single-stranded DNA of a specific nucleotide composition.
1 F1MAF1 (/IDA)
Sequence-specific double-stranded DNA binding GO:1990837
Interacting selectively and non-covalently with double-stranded DNA of a specific nucleotide composition, e.g. GC-rich DNA binding, or with a specific sequence motif or type of DNA, e.g. promotor binding or rDNA binding.
1 G5EFT5 (/IDA)
Promoter-specific chromatin binding GO:1990841
Interacting selectively and non-covalently with a section of chromatin that is associated with gene promoter sequences of DNA.
1 P38532 (/ISO)

There are 208 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
9 F1MAF1 (/IDA) F1Q5S8 (/IDA) F1QJY6 (/IDA) F1R0H1 (/IDA) F6P697 (/IDA) P22813 (/IDA) P38529 (/IDA) P38531 (/IDA) Q1LXV0 (/IDA)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
9 O80982 (/IEP) O81821 (/IEP) P41151 (/IEP) Q8GYY1 (/IEP) Q96320 (/IEP) Q9FK72 (/IEP) Q9LQM7 (/IEP) Q9M1V5 (/IEP) Q9SV12 (/IEP)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
8 A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) Q00613 (/IDA) Q76M53 (/IDA) Q76M54 (/IDA) Q9R0L1 (/IDA)
Lens development in camera-type eye GO:0002088
The process whose specific outcome is the progression of the lens over time, from its formation to the mature structure. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
5 F1Q5S8 (/IMP) F1QJY6 (/IMP) F1R0H1 (/IMP) F6P697 (/IMP) Q1LXV0 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
5 G5EFT5 (/IMP) O81821 (/IMP) P10961 (/IMP) P22813 (/IMP) P38532 (/IMP)
Response to chitin GO:0010200
A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a chitin stimulus.
5 O49403 (/IEP) O80982 (/IEP) Q8GYY1 (/IEP) Q9SCW4 (/IEP) Q9T0D3 (/IEP)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
5 D0VYS2 (/IDA) P22813 (/IDA) Q00613 (/IDA) Q02953 (/IDA) Q03933 (/IDA)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
4 P38529 (/IMP) P38531 (/IMP) Q00613 (/IMP) Q9R0L1 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
4 D0VYS2 (/IDA) P38529 (/IDA) P38531 (/IDA) Q00613 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
4 G5EFT5 (/IMP) P10961 (/IMP) Q5AQ33 (/IMP) Q9R0L1 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Response to light stimulus GO:0009416
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a light stimulus, electromagnetic radiation of wavelengths classified as infrared, visible or ultraviolet light.
3 A0A1D5PC94 (/IDA) P38529 (/IDA) P38530 (/IDA)
Response to high light intensity GO:0009644
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a high light intensity stimulus.
3 O80982 (/IEP) Q9M1V5 (/IEP) Q9SV12 (/IEP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
3 F1MAF1 (/IMP) P38529 (/IMP) P38531 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
3 F1MAF1 (/IMP) Q00613 (/IMP) Q5AQ33 (/IMP)
Regulation of protein heterodimerization activity GO:0043497
Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Cellular response to gamma radiation GO:0071480
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of mRNA polyadenylation GO:1900365
Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033
Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
2 F1MAF1 (/TAS) Q9ULV5 (/TAS)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
2 A0A1D5PC94 (/IDA) P38530 (/IDA)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
2 A0A1D5PC94 (/IMP) P38530 (/IMP)
Positive regulation of gene expression GO:0010628
Any process that increases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
2 A0A060W590 (/IDA) Q8AWA0 (/IDA)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 A0A1D5PC94 (/IDA) P38530 (/IDA)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
2 A0A1D5PC94 (/IMP) P38530 (/IMP)
Negative regulation of protein ubiquitination GO:0031397
Any process that stops, prevents, or reduces the frequency, rate or extent of the addition of ubiquitin groups to a protein.
2 A0A1D5PC94 (/IMP) P38530 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 Q5A4X5 (/IMP) Q6FTT1 (/IMP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Regulation of transcription from RNA polymerase II promoter in response to oxidative stress GO:0043619
Modulation of the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a stimulus indicating the organism is under oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 P38889 (/IMP) Q6FTT1 (/IMP)
Cellular protein complex assembly GO:0043623
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 Q96320 (/IDA) Q9T0D3 (/IDA)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
2 A0A096MK39 (/IMP) P22813 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
2 O49403 (/IDA) O80982 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter GO:0045944
Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter.
2 P38532 (/ISO) P38533 (/ISO)
Protein stabilization GO:0050821
Any process involved in maintaining the structure and integrity of a protein and preventing it from degradation or aggregation.
2 A0A1D5PC94 (/IMP) P38530 (/IMP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
2 A0A096MK39 (/IDA) Q00613 (/IDA)
Maintenance of protein location in nucleus GO:0051457
Any process in which a protein is maintained in the nucleus and prevented from moving elsewhere. These include sequestration within the nucleus, protein stabilization to prevent transport elsewhere and the active retrieval of proteins that escape the nucleus.
2 A0A060W590 (/IMP) Q8AWA0 (/IMP)
Protein heterotrimerization GO:0070208
The formation of a protein heterotrimer, a macromolecular structure consisting of three noncovalently associated subunits, of which not all are identical.
2 Q76M53 (/IDA) Q76M54 (/IDA)
Cellular response to hydrogen peroxide GO:0070301
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
2 C8V7M0 (/IMP) F1MAF1 (/IMP)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Cellular response to diamide GO:0072738
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Positive regulation of cell cycle G2/M phase transition GO:1902751
Any process that activates or increases the frequency, rate or extent of cell cycle G2/M phase transition.
2 P38529 (/IMP) P38531 (/IMP)
Positive regulation of cell cycle G1/S phase transition GO:1902808
Any process that activates or increases the frequency, rate or extent of cell cycle G1/S phase transition.
2 P38529 (/IMP) P38531 (/IMP)
Response to sodium arsenite GO:1903935
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
2 A0A1D5PC94 (/IMP) P38530 (/IMP)
Cellular response to sodium arsenite GO:1903936
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q00613 (/IDA)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 Q9R0L1 (/IMP)
Negative regulation of transcription from RNA polymerase II promoter GO:0000122
Any process that stops, prevents, or reduces the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P38532 (/ISO)
Phosphorelay signal transduction system GO:0000160
A conserved series of molecular signals found in prokaryotes and eukaryotes; involves autophosphorylation of a histidine kinase and the transfer of the phosphate group to an aspartate that then acts as a phospho-donor to response regulator proteins.
1 Q5A4X5 (/ISS)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
1 Q00613 (/IDA)
MAPK cascade GO:0000165
An intracellular protein kinase cascade containing at least a MAPK, a MAPKK and a MAP3K. The cascade can also contain two additional tiers: the upstream MAP4K and the downstream MAP Kinase-activated kinase (MAPKAPK). The kinases in each tier phosphorylate and activate the kinases in the downstream tier to transmit a signal within a cell.
1 P38532 (/ISO)
Response to reactive oxygen species GO:0000302
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a reactive oxygen species stimulus. Reactive oxygen species include singlet oxygen, superoxide, and oxygen free radicals.
1 O49403 (/IMP)
Response to singlet oxygen GO:0000304
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a singlet oxygen stimulus. Singlet oxygen is a dioxygen (O2) molecule in which two 2p electrons have similar spin. Singlet oxygen is more highly reactive than the form in which these electrons are of opposite spin, and it is produced in mutant chloroplasts lacking carotenoids and by leukocytes during metabolic burst.
1 P38889 (/IMP)
Eye development GO:0001654
The process whose specific outcome is the progression of the eye over time, from its formation to the mature structure. The eye is the organ of sight.
1 Q9R0L1 (/IMP)
Response to hypoxia GO:0001666
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 O80982 (/IMP)
In utero embryonic development GO:0001701
The process whose specific outcome is the progression of the embryo in the uterus over time, from formation of the zygote in the oviduct, to birth. An example of this process is found in Mus musculus.
1 P38532 (/IMP)
Embryonic placenta development GO:0001892
The embryonically driven process whose specific outcome is the progression of the placenta over time, from its formation to the mature structure. The placenta is an organ of metabolic interchange between fetus and mother, partly of embryonic origin and partly of maternal origin.
1 P38532 (/IMP)
Lens morphogenesis in camera-type eye GO:0002089
The process in which the anatomical structures of the lens are generated and organized. The lens is a transparent structure in the eye through which light is focused onto the retina. An example of this process is found in Mus musculus.
1 Q5CZP2 (/IMP)
Nematode larval development GO:0002119
The process whose specific outcome is the progression of the nematode larva over time, from its formation to the mature structure. Nematode larval development begins with the newly hatched first-stage larva (L1) and ends with the end of the last larval stage (for example the fourth larval stage (L4) in C. elegans). Each stage of nematode larval development is characterized by proliferation of specific cell lineages and an increase in body size without alteration of the basic body plan. Nematode larval stages are separated by molts in which each stage-specific exoskeleton, or cuticle, is shed and replaced anew.
1 G5EFT5 (/IMP)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P38889 (/IDA)
Transcription, DNA-templated GO:0006351
The cellular synthesis of RNA on a template of DNA.
1 P38889 (/IMP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q8GYY1 (/IDA)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 O49403 (/IEP)
Regulation of transcription, DNA-templated GO:0006355
Any process that modulates the frequency, rate or extent of cellular DNA-templated transcription.
1 Q9R120 (/NAS)
Regulation of transcription from RNA polymerase II promoter GO:0006357
Any process that modulates the frequency, rate or extent of transcription from an RNA polymerase II promoter.
1 P10961 (/IDA)
Transcription from RNA polymerase II promoter GO:0006366
The synthesis of RNA from a DNA template by RNA polymerase II, originating at an RNA polymerase II promoter. Includes transcription of messenger RNA (mRNA) and certain small nuclear RNAs (snRNAs).
1 Q03933 (/TAS)
Protein phosphorylation GO:0006468
The process of introducing a phosphate group on to a protein.
1 P38532 (/IDA)
Defense response GO:0006952
Reactions, triggered in response to the presence of a foreign body or the occurrence of an injury, which result in restriction of damage to the organism attacked or prevention/recovery from the infection caused by the attack.
1 F1MAF1 (/IDA)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 Q942D6 (/IMP)
Response to osmotic stress GO:0006970
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 P38889 (/TAS)
Female meiotic division GO:0007143
A cell cycle process by which the cell nucleus divides as part of a meiotic cell cycle in the female germline.
1 P38532 (/IMP)
Osmosensory signaling via phosphorelay pathway GO:0007234
A series of molecular signals generated in response to osmotic change, as mediated through a phosphorelay system.
1 C8V7M0 (/ISA)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P38532 (/IGI)
Spermatogenesis GO:0007283
The process of formation of spermatozoa, including spermatocytogenesis and spermiogenesis.
1 P38533 (/IMP)
Response to nutrient GO:0007584
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nutrient stimulus.
1 F1MAF1 (/IEP)
Visual perception GO:0007601
The series of events required for an organism to receive a visual stimulus, convert it to a molecular signal, and recognize and characterize the signal. Visual stimuli are detected in the form of photons and are processed to form an image.
1 Q9R0L1 (/IMP)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 Q9R0L1 (/IGI)
Positive regulation of cell proliferation GO:0008284
Any process that activates or increases the rate or extent of cell proliferation.
1 P38532 (/ISO)
Negative regulation of cell proliferation GO:0008285
Any process that stops, prevents or reduces the rate or extent of cell proliferation.
1 P38532 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 G5EFT5 (/IGI)
Determination of adult lifespan GO:0008340
The control of viability and duration in the adult phase of the life-cycle.
1 G5EFT5 (/IMP)
Asymmetric cell division GO:0008356
The asymmetric division of cells to produce two daughter cells with different developmental potentials. It is of fundamental significance for the generation of cell diversity.
1 Q9C635 (/IMP)
Regulation of cell size GO:0008361
Any process that modulates the size of a cell.
1 P38889 (/IMP)
Cellular response to starvation GO:0009267
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of deprivation of nourishment.
1 Q5A4X5 (/IMP)
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
1 Q00613 (/IDA)
MRNA transcription GO:0009299
The cellular synthesis of messenger RNA (mRNA) from a DNA template.
1 P38532 (/ISO)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
1 Q6FTT1 (/IMP)
Response to heat GO:0009408
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P22813 (/TAS)
Response to auxin GO:0009733
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an auxin stimulus.
1 Q9FK72 (/IMP)
Response to abscisic acid GO:0009737
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an abscisic acid stimulus.
1 Q942D6 (/IMP)
Positive gravitropism GO:0009958
The orientation of plant parts towards gravity.
1 Q9FK72 (/IMP)
Response to organonitrogen compound GO:0010243
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organonitrogen stimulus. An organonitrogen compound is formally a compound containing at least one carbon-nitrogen bond.
1 F1MAF1 (/IEP)
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
1 O80982 (/IMP)
Negative regulation of gene expression GO:0010629
Any process that decreases the frequency, rate or extent of gene expression. Gene expression is the process in which a gene's coding sequence is converted into a mature gene product or products (proteins or RNA). This includes the production of an RNA transcript as well as any processing to produce a mature RNA product or an mRNA (for protein-coding genes) and the translation of that mRNA into protein. Protein maturation is included when required to form an active form of a product from an inactive precursor form.
1 F1MAF1 (/IMP)
Negative regulation of cardiac muscle cell apoptotic process GO:0010667
Any process that decreases the rate or extent of cardiac cell apoptotic process, a form of programmed cell death induced by external or internal signals that trigger the activity of proteolytic caspases whose actions dismantle a cardiac muscle cell and result in its death.
1 F1MAF1 (/IMP)
Response to organic cyclic compound GO:0014070
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 F1MAF1 (/IEP)
Response to activity GO:0014823
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an activity stimulus.
1 F1MAF1 (/IEP)
Filamentous growth GO:0030447
The process in which a multicellular organism, a unicellular organism or a group of unicellular organisms grow in a threadlike, filamentous shape.
1 Q5A4X5 (/IMP)
Regulation of fever generation GO:0031620
Any process that modulates the rate or extent of fever generation.
1 P38531 (/IMP)
Negative regulation of TOR signaling GO:0032007
Any process that stops, prevents, or reduces the frequency, rate or extent of TOR signaling.
1 P10961 (/IMP)
Positive regulation of deoxyribonuclease activity GO:0032077
Any process that activates or increases the frequency, rate or extent of deoxyribonuclease activity, the hydrolysis of ester linkages within deoxyribonucleic acid.
1 Q5CZP2 (/IMP)
Regulation of cellular protein metabolic process GO:0032268
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving a protein, occurring at the level of an individual cell.
1 Q9SV12 (/IEP)
Response to estradiol GO:0032355
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 F1MAF1 (/IDA)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 P38532 (/IMP)
Negative regulation of tumor necrosis factor production GO:0032720
Any process that stops, prevents, or reduces the frequency, rate, or extent of tumor necrosis factor production.
1 P38532 (/IMP)
Histone H3-K9 demethylation GO:0033169
The modification of histone H3 by the removal of a methyl group from lysine at position 9 of the histone.
1 Q9R0L1 (/IDA)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
1 F1MAF1 (/IDA)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 O80982 (/IEP)
Cellular response to heat GO:0034605
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P38532 (/ISO)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
1 Q00613 (/IDA)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
1 O80982 (/IEP)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
1 O80982 (/IMP)
Cellular response to unfolded protein GO:0034620
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an unfolded protein stimulus.
1 P38532 (/ISO)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 F1MAF1 (/IEP)
Cellular response to drug GO:0035690
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a drug stimulus. A drug is a substance used in the diagnosis, treatment or prevention of a disease.
1 Q6FTT1 (/IMP)
Cellular response to potassium ion GO:0035865
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a potassium ion stimulus.
1 F1MAF1 (/IEP)
Response to topologically incorrect protein GO:0035966
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
1 G5EFT5 (/IGI)
Response to topologically incorrect protein GO:0035966
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a protein that is not folded in its correct three-dimensional structure.
1 G5EFT5 (/IMP)
Filamentous growth of a population of unicellular organisms in response to starvation GO:0036170
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to deprivation of nourishment.
1 Q5A4X5 (/IMP)
Filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:0036180
The process in which a group of unicellular organisms grow in a threadlike, filamentous shape in response to a biotic (living) stimulus.
1 Q5A4X5 (/IMP)
Positive regulation of multicellular organism growth GO:0040018
Any process that activates or increases the frequency, rate or extent of growth of an organism to reach its usual body size.
1 P38532 (/IMP)
Dauer larval development GO:0040024
The process whose specific outcome is the progression of the dauer larva over time, through the facultative diapause of the dauer (enduring) larval stage, with specialized traits adapted for dispersal and long-term survival, with elevated stress resistance and without feeding.
1 G5EFT5 (/IGI)
Response to hydrogen peroxide GO:0042542
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a hydrogen peroxide (H2O2) stimulus.
1 O80982 (/IEP)
Defense response to bacterium GO:0042742
Reactions triggered in response to the presence of a bacterium that act to protect the cell or organism.
1 P22813 (/IMP)
Camera-type eye development GO:0043010
The process whose specific outcome is the progression of the camera-type eye over time, from its formation to the mature structure. The camera-type eye is an organ of sight that receives light through an aperture and focuses it through a lens, projecting it on a photoreceptor field.
1 Q9R0L1 (/IMP)
Response to amino acid GO:0043200
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 F1MAF1 (/IEP)
Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process GO:0043280
Any process that activates or increases the activity of a cysteine-type endopeptidase involved in the apoptotic process.
1 F1MAF1 (/IMP)
Positive regulation of DNA binding GO:0043388
Any process that increases the frequency, rate or extent of DNA binding. DNA binding is any process in which a gene product interacts selectively with DNA (deoxyribonucleic acid).
1 P22813 (/IDA)
Regulation of protein heterodimerization activity GO:0043497
Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
1 Q00613 (/IMP)
Regulation of protein heterodimerization activity GO:0043497
Any process that modulates the frequency, rate or extent of protein heterodimerization, interacting selectively with a nonidentical protein to form a heterodimer.
1 P38532 (/ISO)
Cellular protein complex assembly GO:0043623
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
1 Q00613 (/IDA)
Cellular protein complex assembly GO:0043623
The aggregation, arrangement and bonding together of a set of components to form a protein complex, occurring at the level of an individual cell.
1 P38532 (/ISO)
Innate immune response GO:0045087
Innate immune responses are defense responses mediated by germline encoded components that directly recognize components of potential pathogens.
1 G5EFT5 (/IMP)
Positive regulation of cell differentiation GO:0045597
Any process that activates or increases the frequency, rate or extent of cell differentiation.
1 Q9R0L1 (/IMP)
Negative regulation of transcription, DNA-templated GO:0045892
Any process that stops, prevents, or reduces the frequency, rate or extent of cellular DNA-templated transcription.
1 P22813 (/IGI)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 P22813 (/IMP)
Positive regulation of transcription, DNA-templated GO:0045893
Any process that activates or increases the frequency, rate or extent of cellular DNA-templated transcription.
1 Q5AQ33 (/TAS)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
1 Q00613 (/IMP)
Positive regulation of mitotic cell cycle GO:0045931
Any process that activates or increases the rate or extent of progression through the mitotic cell cycle.
1 P38532 (/ISO)
Response to cadmium ion GO:0046686
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 O22230 (/IEP)
Conidium formation GO:0048315
The process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
1 C8V7M0 (/IMP)
Root development GO:0048364
The process whose specific outcome is the progression of the root over time, from its formation to the mature structure. The root is the water- and mineral-absorbing part of a plant which is usually underground, does not bear leaves, tends to grow downwards and is typically derived from the radicle of the embryo.
1 Q9FK72 (/IMP)
Cell development GO:0048468
The process whose specific outcome is the progression of the cell over time, from its formation to the mature structure. Cell development does not include the steps involved in committing a cell to a specific fate.
1 Q9R0L1 (/IMP)
Lateral root development GO:0048527
The process whose specific outcome is the progression of the lateral root over time, from its formation to the mature structure. A lateral root is one formed from pericycle cells located on the xylem radius of the root, as opposed to the initiation of the main root from the embryo proper.
1 Q9FK72 (/IMP)
Fruit morphogenesis GO:0048530
The process in which the anatomical structures of a fruit are generated and organized. A fruit is a reproductive body of a seed plant.
1 Q9FK72 (/IMP)
Defense response to Gram-negative bacterium GO:0050829
Reactions triggered in response to the presence of a Gram-negative bacterium that act to protect the cell or organism.
1 G5EFT5 (/IMP)
Defense response to fungus GO:0050832
Reactions triggered in response to the presence of a fungus that act to protect the cell or organism.
1 P22813 (/IMP)
Protein homooligomerization GO:0051260
The process of creating protein oligomers, compounds composed of a small number, usually between three and ten, of identical component monomers. Oligomers may be formed by the polymerization of a number of monomers or the depolymerization of a large protein polymer.
1 P38532 (/ISO)
Embryonic process involved in female pregnancy GO:0060136
A reproductive process occurring in the embryo or fetus that allows the embryo or fetus to develop within the mother.
1 P38532 (/IMP)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 Q00613 (/IDA)
Positive regulation of transcription from RNA polymerase II promoter in response to heat stress GO:0061408
Any process that increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of a heat stimulus, a temperature stimulus above the optimal temperature for that organism.
1 P38532 (/ISO)
Regulation of establishment of protein localization to chromosome GO:0070202
Any process that modulates the frequency, rate or extent of the directed movement of a protein to a specific location on a chromosome.
1 P10961 (/IMP)
Protein homotrimerization GO:0070207
The formation of a protein homotrimer, a macromolecular structure consisting of three noncovalently associated identical subunits.
1 P38532 (/ISO)
Lens fiber cell differentiation GO:0070306
The process in which a relatively unspecialized cell acquires specialized features of a lens fiber cell, any of the elongated, tightly packed cells that make up the bulk of the mature lens in the camera-type eye. The cytoplasm of a lens fiber cell is devoid of most intracellular organelles including the cell nucleus, and contains primarily crystallins, a group of water-soluble proteins expressed in vary large quantities.
1 Q5CZP2 (/IMP)
Cellular response to lipopolysaccharide GO:0071222
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
1 F1MAF1 (/IEP)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 F1MAF1 (/IDA)
Cellular response to amino acid stimulus GO:0071230
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an amino acid stimulus. An amino acid is a carboxylic acids containing one or more amino groups.
1 F1MAF1 (/IEP)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 Q00613 (/IDA)
Cellular response to cadmium ion GO:0071276
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a cadmium (Cd) ion stimulus.
1 P38532 (/ISO)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 Q00613 (/IDA)
Cellular response to copper ion GO:0071280
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a copper ion stimulus.
1 P38532 (/ISO)
Cellular response to estradiol stimulus GO:0071392
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of stimulus by estradiol, a C18 steroid hormone hydroxylated at C3 and C17 that acts as a potent estrogen.
1 F1MAF1 (/IDA)
Cellular response to organic cyclic compound GO:0071407
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an organic cyclic compound stimulus.
1 F1MAF1 (/IDA)
Cellular response to hypoxia GO:0071456
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension. Hypoxia, defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95%, results in metabolic adaptation at both the cellular and organismal level.
1 O80982 (/IEP)
Cellular response to osmotic stress GO:0071470
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating an increase or decrease in the concentration of solutes outside the organism or cell.
1 C8V7M0 (/IMP)
Cellular hyperosmotic response GO:0071474
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of detection of, or exposure to, a hyperosmotic environment, i.e. an environment with a higher concentration of solutes than the organism or cell.
1 C8V7M0 (/IMP)
Cellular response to radiation GO:0071478
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an electromagnetic radiation stimulus. Electromagnetic radiation is a propagating wave in space with electric and magnetic components. These components oscillate at right angles to each other and to the direction of propagation.
1 F1MAF1 (/IDA)
Cellular response to gamma radiation GO:0071480
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
1 Q00613 (/IDA)
Cellular response to gamma radiation GO:0071480
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a gamma radiation stimulus. Gamma radiation is a form of electromagnetic radiation (EMR) or light emission of a specific frequency produced from sub-atomic particle interaction, such as electron-positron annihilation and radioactive decay. Gamma rays are generally characterized as EMR having the highest frequency and energy, and also the shortest wavelength, within the electromagnetic radiation spectrum.
1 P38532 (/ISO)
Cellular response to diamide GO:0072738
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
1 Q00613 (/IDA)
Cellular response to diamide GO:0072738
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a diamide (N,N,N',N'-tetramethyldiazene-1,2-dicarboxamide) stimulus.
1 P38532 (/ISO)
Regulation of conidium formation GO:0075306
Any process that modulates the frequency, rate or extent of conidium formation, a process of producing non-motile spores, called conidia, via mitotic asexual reproduction in higher fungi. Conidia are haploid cells genetically identical to their haploid parent. They are produced by conversion of hyphal elements, or are borne on sporogenous cells on or within specialized structures termed conidiophores, and participate in dispersal of the fungus.
1 C8V7M0 (/IMP)
Negative regulation of inclusion body assembly GO:0090084
Any process that decreases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
1 F1MAF1 (/IMP)
Positive regulation of inclusion body assembly GO:0090261
Any process that increases the rate, frequency, or extent of inclusion body assembly. Inclusion body assembly is the aggregation, arrangement and bonding together of a set of components to form an inclusion body.
1 F1MAF1 (/IMP)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
1 Q00613 (/IDA)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
1 P38532 (/ISO)
Regulation of cellular response to heat GO:1900034
Any process that modulates the frequency, rate or extent of cellular response to heat.
1 Q00613 (/TAS)
Positive regulation of cellular response to heat GO:1900036
Any process that activates or increases the frequency, rate or extent of cellular response to heat.
1 Q02953 (/IMP)
Regulation of endoplasmic reticulum unfolded protein response GO:1900101
Any process that modulates the frequency, rate or extent of endoplasmic reticulum unfolded protein response.
1 P38889 (/IMP)
Positive regulation of mRNA polyadenylation GO:1900365
Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.
1 Q00613 (/IMP)
Positive regulation of mRNA polyadenylation GO:1900365
Any process that activates or increases the frequency, rate or extent of mRNA polyadenylation.
1 P38532 (/ISO)
Regulation of conjugation with cellular fusion by regulation of transcription from RNA polymerase II promoter GO:1900406
A regulation of transcription from RNA polymerase II promoter that results in regulation of conjugation with cellular fusion.
1 O14283 (/IMP)
Regulation of cellular response to oxidative stress by regulation of transcription from RNA polymerase II promoter GO:1900427
A regulation of transcription from RNA polymerase II promoter that results in regulation of cellular response to oxidative stress.
1 O14283 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to starvation GO:1900436
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to starvation.
1 Q5A4X5 (/IMP)
Positive regulation of filamentous growth of a population of unicellular organisms in response to biotic stimulus GO:1900445
Any process that activates or increases the frequency, rate or extent of filamentous growth of a population of unicellular organisms in response to biotic stimulus.
1 Q5A4X5 (/IMP)
Negative regulation of neuron death GO:1901215
Any process that stops, prevents or reduces the frequency, rate or extent of neuron death.
1 F1MAF1 (/IMP)
Response to peptide GO:1901652
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a peptide stimulus.
1 F1MAF1 (/IEP)
Positive regulation of apoptotic DNA fragmentation GO:1902512
Any process that activates or increases the frequency, rate or extent of apoptotic DNA fragmentation.
1 F1MAF1 (/IMP)
Cellular response to sodium arsenite GO:1903936
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
1 Q00613 (/IDA)
Cellular response to sodium arsenite GO:1903936
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a sodium arsenite stimulus.
1 P38532 (/ISO)
Cellular response to angiotensin GO:1904385
\Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an angiotensin stimulus. Angiotensin is any of three physiologically active peptides (angiotensin II, III, or IV) processed from angiotensinogen.\
1 F1MAF1 (/IDA)
Positive regulation of microtubule binding GO:1904528
Any process that activates or increases the frequency, rate or extent of microtubule binding.
1 F1MAF1 (/IMP)
Cellular response to nitroglycerin GO:1904843
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitroglycerin stimulus.
1 F1MAF1 (/IEP)
Cellular response to L-glutamine GO:1904845
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a L-glutamine stimulus.
1 F1MAF1 (/IEP)
Response to hypobaric hypoxia GO:1990910
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating lowered oxygen tension combined with low atmospheric pressure. Hypoxia is defined as a decline in O2 levels below normoxic levels of 20.8 - 20.95% and hypobaric is defined as atmospheric pressure below 0.74 atm (greater than 2,500 m above sea level).
1 F1MAF1 (/IEP)
Response to psychosocial stress GO:1990911
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of exposure to aversive or demanding psychological and social conditions that tax or exceed the behavioral resources of the organism.
1 F1MAF1 (/IEP)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033
Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
1 Q00613 (/IMP)
Negative regulation of double-strand break repair via nonhomologous end joining GO:2001033
Any process that stops, prevents or reduces the frequency, rate or extent of double-strand break repair via nonhomologous end joining.
1 P38532 (/ISO)

There are 47 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
29 A0A096MK39 (/IDA) A0A1D5PC94 (/IDA) D0VYS2 (/IDA) F1MAF1 (/IDA) G5EFT5 (/IDA) I1LGH5 (/IDA) I1MPZ9 (/IDA) K7LH36 (/IDA) O14283 (/IDA) O49403 (/IDA)
(19 more)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
12 A0A1D5PC94 (/IDA) D0VYS2 (/IDA) F1MAF1 (/IDA) K7LH36 (/IDA) P38529 (/IDA) P38530 (/IDA) P38531 (/IDA) P38532 (/IDA) P38533 (/IDA) Q00613 (/IDA)
(2 more)
Nuclear chromatin GO:0000790
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome in the nucleus.
4 A0A1D5PC94 (/IDA) P38530 (/IDA) P38531 (/IDA) Q02953 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
4 E9PMQ6 (/IDA) P38889 (/IDA) Q00613 (/IDA) Q02953 (/IDA)
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 G5EFT5 (/ISS) P38529 (/ISS) Q08DJ8 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 E9PMQ6 (/IDA) Q00613 (/IDA) Q03933 (/IDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
3 A0A060W590 (/IDA) Q00613 (/IDA) Q8AWA0 (/IDA)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
3 A0A024R6X7 (/IDA) E5RK26 (/IDA) Q9ULV5 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
3 P38529 (/ISS) P38532 (/ISS) Q08DJ8 (/ISS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P38532 (/ISO) P38533 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P38529 (/ISS) Q08DJ8 (/ISS)
Protein-DNA complex GO:0032993
A macromolecular complex containing both protein and DNA molecules.
2 P10961 (/IMP) P22121 (/IMP)
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
2 G5EFT5 (/IDA) Q00613 (/IDA)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
2 P38532 (/ISS) Q08DJ8 (/ISS)
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
1 Q00613 (/IDA)
Kinetochore GO:0000776
A multisubunit complex that is located at the centromeric region of DNA and provides an attachment point for the spindle microtubules.
1 P38532 (/ISO)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
1 P22813 (/IDA)
Euchromatin GO:0000791
A dispersed and relatively uncompacted form of chromatin.
1 F1MAF1 (/IDA)
Heterochromatin GO:0000792
A compact and highly condensed form of chromatin.
1 F1MAF1 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q5AQ33 (/IC)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 Q00613 (/IMP)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P38889 (/IPI)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
1 P38532 (/ISO)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
1 Q00613 (/TAS)
Polytene chromosome GO:0005700
A type of chromosome in a polyploid cell, formed when multiple copies of homologous chromosomes are aligned side by side to give a giant chromosome in which distinct chromosome bands are readily visible.
1 P22813 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 P38532 (/ISO)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 Q00613 (/IDA)
Centrosome GO:0005813
A structure comprised of a core structure (in most organisms, a pair of centrioles) and peripheral material from which a microtubule-based structure, such as a spindle apparatus, is organized. Centrosomes occur close to the nucleus during interphase in many eukaryotic cells, though in animal cells it changes continually during the cell-division cycle.
1 P38532 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 P38532 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
1 Q00613 (/TAS)
PML body GO:0016605
A class of nuclear body; they react against SP100 auto-antibodies (PML, promyelocytic leukemia); cells typically contain 10-30 PML bodies per nucleus; alterations in the localization of PML bodies occurs after viral infection.
1 P38532 (/ISO)
Nuclear speck GO:0016607
A discrete extra-nucleolar subnuclear domain, 20-50 in number, in which splicing factors are seen to be localized by immunofluorescence microscopy.
1 Q9R0L1 (/ISO)
Protein complex GO:0043234
A stable macromolecular complex composed (only) of two or more polypeptide subunits along with any covalently attached molecules (such as lipid anchors or oligosaccharide) or non-protein prosthetic groups (such as nucleotides or metal ions). Prosthetic group in this context refers to a tightly bound cofactor. The component polypeptide subunits may be identical.
1 P38532 (/IPI)
Pronucleus GO:0045120
The nucleus of either the ovum or the spermatozoon following fertilization. Thus, in the fertilized ovum, there are two pronuclei, one originating from the ovum, the other from the spermatozoon that brought about fertilization; they approach each other, but do not fuse until just before the first cleavage, when each pronucleus loses its membrane to release its contents.
1 P38532 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 Q00613 (/IDA)
Perinuclear region of cytoplasm GO:0048471
Cytoplasm situated near, or occurring around, the nucleus.
1 P38532 (/ISO)
Nuclear stress granule GO:0097165
A dense aggregation in the nucleus composed of proteins and RNAs that appear when the cell is under stress.
1 P38532 (/ISO)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 Q00613 (/IDA)
Mitotic spindle pole GO:0097431
Either of the ends of a mitotic spindle, a spindle that forms as part of mitosis, where spindle microtubules are organized; usually contains a microtubule organizing center and accessory molecules, spindle microtubules and astral microtubules.
1 P38532 (/ISO)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 Q00613 (/IDA)
Ribonucleoprotein complex GO:1990904
A macromolecular complex containing both protein and RNA molecules.
1 P38532 (/ISO)