The name of this superfamily has been modified since the most recent official CATH+ release (v4_2_0). At the point of the last release, this superfamily was named:

"
Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 264920: Histone H1oo

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 4 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleosomal DNA binding GO:0031492
Interacting selectively and non-covalently with the DNA portion of a nucleosome.
11 D3ZEG0 (/ISS) F1SPK2 (/ISS) G1LCQ0 (/ISS) G3HVM0 (/ISS) G3QEM7 (/ISS) G7N7U0 (/ISS) H2P9C9 (/ISS) H2QNC6 (/ISS) Q3HNG7 (/ISS) Q8IZA3 (/ISS)
(1 more)
DNA binding GO:0003677
Any molecular function by which a gene product interacts selectively and non-covalently with DNA (deoxyribonucleic acid).
1 Q8VIK3 (/ISA)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P15308 (/IPI)
Nucleosomal DNA binding GO:0031492
Interacting selectively and non-covalently with the DNA portion of a nucleosome.
1 Q8VIK3 (/IDA)

There are 7 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleosome positioning GO:0016584
Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
11 D3ZEG0 (/ISS) F1SPK2 (/ISS) G1LCQ0 (/ISS) G3HVM0 (/ISS) G3QEM7 (/ISS) G7N7U0 (/ISS) H2P9C9 (/ISS) H2QNC6 (/ISS) Q3HNG7 (/ISS) Q8IZA3 (/ISS)
(1 more)
Regulation of DNA methylation GO:0044030
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
11 D3ZEG0 (/ISS) F1SPK2 (/ISS) G1LCQ0 (/ISS) G3HVM0 (/ISS) G3QEM7 (/ISS) G7N7U0 (/ISS) H2P9C9 (/ISS) H2QNC6 (/ISS) Q3HNG7 (/ISS) Q8IZA3 (/ISS)
(1 more)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
11 D3ZEG0 (/ISS) F1SPK2 (/ISS) G1LCQ0 (/ISS) G3HVM0 (/ISS) G3QEM7 (/ISS) G7N7U0 (/ISS) H2P9C9 (/ISS) H2QNC6 (/ISS) Q3HNG7 (/ISS) Q8IZA3 (/ISS)
(1 more)
Nucleosome assembly GO:0006334
The aggregation, arrangement and bonding together of a nucleosome, the beadlike structural units of eukaryotic chromatin composed of histones and DNA.
1 Q8VIK3 (/ISA)
Nucleosome positioning GO:0016584
Ordering of successions of nucleosomes into regular arrays so that nucleosomes are positioned at defined distances from one another.
1 Q8VIK3 (/IDA)
Regulation of DNA methylation GO:0044030
Any process that modulates the frequency, rate or extent of the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine.
1 Q8VIK3 (/IDA)
Negative regulation of stem cell differentiation GO:2000737
Any process that stops, prevents or reduces the frequency, rate or extent of stem cell differentiation.
1 Q8VIK3 (/IMP)

There are 6 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
10 D3ZEG0 (/ISS) F1SPK2 (/ISS) G1LCQ0 (/ISS) G3HVM0 (/ISS) G3QEM7 (/ISS) G7N7U0 (/ISS) H2P9C9 (/ISS) H2QNC6 (/ISS) Q8IZA3 (/ISS) U3KMC4 (/ISS)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P15308 (/IDA) Q3HNG7 (/IDA) Q8VIK3 (/IDA)
Chromatin GO:0000785
The ordered and organized complex of DNA, protein, and sometimes RNA, that forms the chromosome.
2 A0A0R4IAV0 (/IDA) Q5XJ47 (/IDA)
Female germ cell nucleus GO:0001674
The nucleus of the female germ cell, a reproductive cell in females.
1 Q8VIK3 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q8IZA3 (/IDA)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
1 Q8VIK3 (/ISO)