CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Polycomb group protein FIE2

Enzyme Information

UniProtKB Entries (2)

G1KPH4
G1KPH4_ANOCA
Anolis carolinensis
Uncharacterized protein
Q15910
EZH2_HUMAN
Homo sapiens
Histone-lysine N-methyltransferase EZH2

PDB Structure

PDB 5IJ7
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Polycomb repressive complex 2 structure with inhibitor reveals a mechanism of activation and drug resistance.
Brooun, A., Gajiwala, K.S., Deng, Y.L., Liu, W., Bolanos, B., Bingham, P., He, Y.A., Diehl, W., Grable, N., Kung, P.P., Sutton, S., Maegley, K.A., Yu, X., Stewart, A.E.
Nat Commun