CATH Classification

Domain Context

CATH Clusters

Superfamily ATP-grasp fold, A domain
Functional Family D-alanine--D-alanine ligase

Enzyme Information

6.3.2.4
D-alanine--D-alanine ligase.
based on mapping to UniProt B2I1J3
ATP + 2 D-alanine = ADP + phosphate + D-alanyl-D-alanine.
-!- Involved with EC 6.3.2.7 or EC 6.3.2.13, EC 6.3.2.8, EC 6.3.2.9 and EC 6.3.2.10 in the synthesis of a cell-wall peptide.

UniProtKB Entries (1)

B2I1J3
DDL_ACIBC
Acinetobacter baumannii ACICU
D-alanine--D-alanine ligase

PDB Structure

PDB 5D8D
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The crystal structure of the D-alanine-D-alanine ligase from Acinetobacter baumannii suggests a flexible conformational change in the central domain before nucleotide binding
Huynh, K.H., Hong, M.K., Lee, C., Tran, H.T., Lee, S.H., Ahn, Y.J., Cha, S.S., Kang, L.W.
J. Microbiol.