CATH Classification

Domain Context

CATH Clusters

Superfamily Serralysin-like metalloprotease, C-terminal
Functional Family Hemolysin toxin protein A

Enzyme Information

4.6.1.1
Adenylate cyclase.
based on mapping to UniProt P0DKX7
ATP = 3',5'-cyclic AMP + diphosphate.
-!- Also acts on dATP to form 3',5'-cyclic dAMP. -!- Requires pyruvate. -!- Activated by NAD(+) in presence of EC 2.4.2.31.

UniProtKB Entries (1)

P0DKX7
CYAA_BORPE
Bordetella pertussis Tohama I
Bifunctional hemolysin/adenylate cyclase

PDB Structure

PDB 5CXL
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Calcium-Driven Folding of RTX Domain beta-Rolls Ratchets Translocation of RTX Proteins through Type I Secretion Ducts.
Bumba, L., Masin, J., Macek, P., Wald, T., Motlova, L., Bibova, I., Klimova, N., Bednarova, L., Veverka, V., Kachala, M., Svergun, D.I., Barinka, C., Sebo, P.
Mol.Cell