CATH Classification

Domain Context

CATH Clusters

Superfamily 3.40.47.10
Functional Family Probable Hydroxymethylglutaryl-CoA synthase

Enzyme Information

2.3.3.-
Acyl groups converted into alkyl groups on transfer.
based on mapping to UniProt P40830
2.3.3.10
Hydroxymethylglutaryl-CoA synthase.
based on mapping to UniProt P40830
Acetyl-CoA + H(2)O + acetoacetyl-CoA = (S)-3-hydroxy-3-methylglutaryl-CoA + CoA.
-!- Formerly EC 4.1.3.5.

UniProtKB Entries (1)

P40830
PKSG_BACSU
Bacillus subtilis subsp. subtilis str. 168
Polyketide biosynthesis 3-hydroxy-3-methylglutaryl-ACP synthase PksG

PDB Structure

PDB 4YXQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
PksG, a HMG-CoA Synthase from Bacillus subtilis
Nair, A.V., Race, P.R., Till, M.
To Be Published