CATH Domain 4wiiA01

CATH Classification

Level	CATH Code	Description
	3	Alpha Beta
	3.30	2-Layer Sandwich
	3.30.70	Alpha-Beta Plaits
	3.30.70.330	RRM (RNA recognition motif) domain

Domain Context

CATH Clusters

Superfamily	3.30.70.330
Functional Family	Paraspeckle component 1

Enzyme Information

UniProtKB Entries (1)

SFPQ_HUMAN

Homo sapiens

Splicing factor, proline- and glutamine-rich

PDB Structure

PDB	4WII
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	The structure of human SFPQ reveals a coiled-coil mediated polymer essential for functional aggregation in gene regulation. Lee, M., Sadowska, A., Bekere, I., Ho, D., Gully, B.S., Lu, Y., Iyer, K.S., Trewhella, J., Fox, A.H., Bond, C.S. Nucleic Acids Res.