CATH Classification

Domain Context

CATH Clusters

Superfamily Aromatic compound dioxygenase
Functional Family Protocatechuate 3,4-dioxygenase subunit beta

Enzyme Information

1.13.11.3
Protocatechuate 3,4-dioxygenase.
based on mapping to UniProt P00436
3,4-dihydroxybenzoate + O(2) = 3-carboxy-cis,cis-muconate.
-!- The enzyme, which participates in the degradation of aromatic compounds, catalyzes the intradiol addition of both oxygen atoms from molecular oxygen, resulting in ortho-cleavage of the aromatic ring. -!- The type of cleavage leads to mineralization via the intermediate 3-oxoadipate. -!- Formerly EC 1.13.1.3 and EC 1.99.2.3.

UniProtKB Entries (1)

P00437
PCXB_PSEPU
Pseudomonas putida
Protocatechuate 3,4-dioxygenase beta chain

PDB Structure

PDB 4WHO
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Crystal structures of alkylperoxo and anhydride intermediates in an intradiol ring-cleaving dioxygenase.
Knoot, C.J., Purpero, V.M., Lipscomb, J.D.
Proc.Natl.Acad.Sci.USA