CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.10490 | Glucose-6-phosphate isomerase like protein; domain 1 |
Domain Context
CATH Clusters
| Superfamily | Glucose-6-phosphate isomerase like protein; domain 1 |
| Functional Family | Glutamine--fructose-6-phosphate aminotransferase [isomerizing] |
Enzyme Information
| 2.6.1.16 |
Glutamine--fructose-6-phosphate transaminase (isomerizing).
based on mapping to UniProt A0A0J9X200
L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.
-!- Although the overall reaction is that of a transferase, the mechanism involves the formation of ketimine between fructose 6-phosphate and a 6-amino group from a lysine residue at the active site, which is subsequently displaced by ammonia (transamidination). -!- Formerly EC 5.3.1.19.
|
UniProtKB Entries (1)
| A0A0J9X200 |
A0A0J9X200_STAAU
Staphylococcus aureus subsp. aureus
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
|
PDB Structure
| PDB | 4S1W |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of a putative Glutamine--Fructose-6-Phosphate Aminotransferase from Staphylococcus aureus subsp. aureus Mu50
To be Published
|