CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.720 | NAD(P)-binding Rossmann-like Domain |
Domain Context
CATH Clusters
| Superfamily | NAD(P)-binding Rossmann-like Domain |
| Functional Family | D-3-phosphoglycerate dehydrogenase-related protein |
Enzyme Information
| 1.1.1.95 |
Phosphoglycerate dehydrogenase.
based on mapping to UniProt A0A0H2UKZ7
3-phospho-D-glycerate + NAD(+) = 3-phosphonooxypyruvate + NADH.
-!- Catalyzes the first committed and rate-limiting step in the phosphoserine pathway of serine biosynthesis. -!- The reaction occurs predominantly in the direction of reduction. -!- The enzyme from the bacterium Escherichia coli also catalyzes the activity of EC 1.1.1.399.
|
UniProtKB Entries (1)
| A0A0H2UKZ7 |
A0A0H2UKZ7_VIBC3
Vibrio cholerae O395
D-3-phosphoglycerate dehydrogenase-related protein
|
PDB Structure
| PDB | 4S1V |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal Structure of Phosphoglycerate Oxidoreductase from Vibrio Cholerae O395
To be Published
|