CATH Classification

Domain Context

CATH Clusters

Superfamily 1.20.1050.10
Functional Family Glutathione S transferase E9

Enzyme Information

2.5.1.18
Glutathione transferase.
based on mapping to UniProt A1ZB72
RX + glutathione = HX + R-S-glutathione.
-!- A group of enzymes of broad specificity. -!- R may be an aliphatic, aromatic or heterocyclic group; X may be a sulfate, nitrile or halide group. -!- Also catalyzes the addition of aliphatic epoxides and arene oxides to glutathione, the reduction of polyol nitrate by glutathione to polyol and nitrile, certain isomerization reactions and disulfide interchange. -!- Formerly EC 1.8.6.1, EC 2.5.1.12, EC 2.5.1.13, EC 2.5.1.14 and EC 4.4.1.7.

UniProtKB Entries (1)

A1ZB72
A1ZB72_DROME
Drosophila melanogaster
Glutathione S transferase E7

PDB Structure

PDB 4PNG
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Comparison of epsilon- and delta-class glutathione S-transferases: the crystal structures of the glutathione S-transferases DmGSTE6 and DmGSTE7 from Drosophila melanogaster.
Scian, M., Le Trong, I., Mazari, A.M., Mannervik, B., Atkins, W.M., Stenkamp, R.E.
Acta Crystallogr.,Sect.D
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