CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.50 | Rossmann fold |
|
3.40.50.450 |
Domain Context
CATH Clusters
| Superfamily | 3.40.50.450 |
| Functional Family | Putative 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 |
Enzyme Information
| 3.2.2.- |
Hydrolyzing N-glycosyl compounds.
based on mapping to UniProt O43598
|
UniProtKB Entries (1)
| O43598 |
DNPH1_HUMAN
Homo sapiens
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
|
PDB Structure
| PDB | 4P5E |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
6-(Hetero)Arylpurine nucleotides as inhibitors of the oncogenic target DNPH1: Synthesis, structural studies and cytotoxic activities.
Eur.J.Med.Chem.
|