CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.60 | Sandwich |
|
2.60.120 | Jelly Rolls |
|
2.60.120.590 | Alpha-ketoglutarate-dependent dioxygenase AlkB-like |
Domain Context
CATH Clusters
| Superfamily | Alpha-ketoglutarate-dependent dioxygenase AlkB-like |
| Functional Family | RNA demethylase ALKBH5 |
Enzyme Information
| 1.14.11.- |
With 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors.
based on mapping to UniProt Q6P6C2
|
UniProtKB Entries (1)
| Q6P6C2 |
ALKB5_HUMAN
Homo sapiens
RNA demethylase ALKBH5
|
PDB Structure
| PDB | 4NJ4 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Structure of human RNA N6-methyladenine demethylase ALKBH5 provides insights into its mechanisms of nucleic acid recognition and demethylation.
Nucleic Acids Res.
|