CATH Classification

Domain Context

CATH Clusters

Superfamily Phosphorylase Kinase; domain 1
Functional Family Ndr Ser/Thr kinase-like protein

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt P53894
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

P43563
MOB2_YEAST
Saccharomyces cerevisiae S288C
CBK1 kinase activator protein MOB2

PDB Structure

PDB 4LQQ
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
The Structure of an NDR/LATS Kinase-Mob Complex Reveals a Novel Kinase-Coactivator System and Substrate Docking Mechanism.
Gogl, G., Schneider, K.D., Yeh, B.J., Alam, N., Nguyen Ba, A.N., Moses, A.M., Hetenyi, C., Remenyi, A., Weiss, E.L.
Plos Biol.