CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | Chalcone synthase Pks10 |
Enzyme Information
| 2.3.1.- |
Transferring groups other than amino-acyl groups.
based on mapping to UniProt P9WPF3
|
| 2.3.1.74 |
Naringenin-chalcone synthase.
based on mapping to UniProt P9WPF3
3 malonyl-CoA + 4-coumaroyl-CoA = 4 CoA + naringenin chalcone + 3 CO(2).
-!- In the presence of NADH and a reductase, 6'-deoxychalcone is produced.
|
UniProtKB Entries (1)
| P9WPF3 |
PKS11_MYCTU
Mycobacterium tuberculosis H37Rv
Alpha-pyrone synthesis polyketide synthase-like Pks11
|
PDB Structure
| PDB | 4JAO |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of Mycobacterium tuberculosis polyketide synthase 11 (PKS11) reveals intermediates in the synthesis of methyl-branched alkylpyrones.
J.Biol.Chem.
|