CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.30 | 2-Layer Sandwich | |
3.30.300 | GMP Synthetase; Chain A, domain 3 | |
3.30.300.30 | ANL, C-terminal domain |
Domain Context
CATH Clusters
Superfamily | 3.30.300.30 |
Functional Family | Probable 4-coumarate--CoA ligase 1 |
Enzyme Information
1.13.12.7 |
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing).
based on mapping to UniProt P08659
Photinus luciferin + O(2) + ATP = oxidized Photinus luciferin + CO(2) + AMP + diphosphate + light.
-!- Photinus (firefly) is a bioluminescent insect. -!- The first step in the reaction is the formation of an acid anhydride between the carboxylic group and AMP, with the release of diphosphate. -!- The enzyme may be assayed by measurement of light emission.
|
UniProtKB Entries (1)
P08659 |
LUCI_PHOPY
Photinus pyralis
Luciferin 4-monooxygenase
|
PDB Structure
PDB | 4G36 |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.
Biochemistry
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