CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
2 | Mainly Beta |
|
2.30 | Roll |
|
2.30.38 | Luciferase; domain 3 |
|
2.30.38.10 | Luciferase; Domain 3 |
Domain Context
CATH Clusters
| Superfamily | Luciferase; Domain 3 |
| Functional Family | 4 coumarate CoA ligase |
Enzyme Information
| 1.13.12.7 |
Photinus-luciferin 4-monooxygenase (ATP-hydrolyzing).
based on mapping to UniProt P08659
Photinus luciferin + O(2) + ATP = oxidized Photinus luciferin + CO(2) + AMP + diphosphate + light.
-!- Photinus (firefly) is a bioluminescent insect. -!- The first step in the reaction is the formation of an acid anhydride between the carboxylic group and AMP, with the release of diphosphate. -!- The enzyme may be assayed by measurement of light emission.
|
UniProtKB Entries (1)
| P08659 |
LUCI_PHOPY
Photinus pyralis
Luciferin 4-monooxygenase
|
PDB Structure
| PDB | 4G36 |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
Crystal structure of firefly luciferase in a second catalytic conformation supports a domain alternation mechanism.
Biochemistry
|