CATH Classification
Level | CATH Code | Description |
---|---|---|
3 | Alpha Beta | |
3.40 | 3-Layer(aba) Sandwich | |
3.40.50 | Rossmann fold | |
3.40.50.140 |
Domain Context
CATH Clusters
Superfamily | 3.40.50.140 |
Functional Family | DNA topoisomerase III (Eurofung) |
Enzyme Information
5.99.1.2 |
DNA topoisomerase.
based on mapping to UniProt Q13472
ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.
-!- Brings about the conversion of one topological isomer of DNA into another, e.g. the relaxation of superhelical turns in DNA, the interconversion of simple and knotted rings of single-stranded DNA, and the intertwisting of single-stranded rings of complementary sequences (cf. EC 5.99.1.3).
|
UniProtKB Entries (1)
Q9H9A7 |
RMI1_HUMAN
Homo sapiens
RecQ-mediated genome instability protein 1
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PDB Structure
PDB | 4CGY |
External Links | |
Method | X-RAY DIFFRACTION |
Organism | |
Primary Citation |
Structural and Mechanistic Insight Into Holliday-Junction Dissolution by Topoisomerase Iiialpha and Rmi1
Nat.Struct.Mol.Biol.
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