CATH Classification

Domain Context

CATH Clusters

Superfamily YVTN repeat-like/Quinoprotein amine dehydrogenase
Functional Family Vpr (HIV-1) binding protein

Enzyme Information

2.7.11.1
Non-specific serine/threonine protein kinase.
based on mapping to UniProt Q9Y4B6
ATP + a protein = ADP + a phosphoprotein.
-!- This is a heterogeneous group of serine/threonine protein kinases that do not have an activating compound and are either non-specific or their specificity has not been analyzed to date. -!- Formerly EC 2.7.1.37 and EC 2.7.1.70.

UniProtKB Entries (1)

Q9Y3Z3
SAMH1_HUMAN
Homo sapiens
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

PDB Structure

PDB 4CC9
External Links
Method X-RAY DIFFRACTION
Organism
Primary Citation
Structural Basis of Lentiviral Subversion of a Cellular Protein Degradation Pathway.
Schwefel, D., Groom, H.C.T., Boucherit, V.C., Christodoulou, E., Walker, P.A., Stoye, J.P., Bishop, K.N., Taylor, I.A.
Nature