CATH Classification
| Level | CATH Code | Description |
|---|---|---|
|
3 | Alpha Beta |
|
3.40 | 3-Layer(aba) Sandwich |
|
3.40.47 | Peroxisomal Thiolase; Chain A, domain 1 |
|
3.40.47.10 | Thiolase/Chalcone synthase |
Domain Context
CATH Clusters
| Superfamily | 3.40.47.10 |
| Functional Family | 3-ketoacyl-CoA thiolase, mitochondrial |
Enzyme Information
| 2.3.1.16 |
Acetyl-CoA C-acyltransferase.
based on mapping to UniProt P42765
Acyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
|
UniProtKB Entries (1)
| P42765 |
THIM_HUMAN
Homo sapiens
3-ketoacyl-CoA thiolase, mitochondrial
|
PDB Structure
| PDB | 4C2J |
| External Links | |
| Method | X-RAY DIFFRACTION |
| Organism | |
| Primary Citation |
The Crystal Structure of Human Mitochondrial 3-Ketoacyl-Coa Thiolase (T1): Insight Into the Reaction Mechanism of its Thiolase and Thioesterase Activities
Acta Crystallogr.,Sect.D
|